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Items: 1 to 20 of 68

1.

Amelioration of Cognitive Deficit by Embelin in a Scopolamine-Induced Alzheimer's Disease-Like Condition in a Rat Model.

Bhuvanendran S, Kumari Y, Othman I, Shaikh MF.

Front Pharmacol. 2018 Jun 25;9:665. doi: 10.3389/fphar.2018.00665. eCollection 2018.

2.

sAPPβ and sAPPα increase structural complexity and E/I input ratio in primary hippocampal neurons and alter Ca2+ homeostasis and CREB1-signaling.

Hesse R, von Einem B, Wagner F, Bott P, Schwanzar D, Jackson RJ, Föhr KJ, Lausser L, Kroker KS, Proepper C, Walther P, Kestler HA, Spires-Jones TL, Boeckers T, Rosenbrock H, von Arnim CAF.

Exp Neurol. 2018 Jun;304:1-13. doi: 10.1016/j.expneurol.2018.02.010. Epub 2018 Feb 18.

PMID:
29466703
3.

Cyclic nucleotide signaling changes associated with normal aging and age-related diseases of the brain.

Kelly MP.

Cell Signal. 2018 Jan;42:281-291. doi: 10.1016/j.cellsig.2017.11.004. Epub 2017 Nov 23. Review.

PMID:
29175000
4.

Network-Driven Proteogenomics Unveils an Aging-Related Imbalance in the Olfactory IκBα-NFκB p65 Complex Functionality in Tg2576 Alzheimer's Disease Mouse Model.

Palomino-Alonso M, Lachén-Montes M, González-Morales A, Ausín K, Pérez-Mediavilla A, Fernández-Irigoyen J, Santamaría E.

Int J Mol Sci. 2017 Oct 27;18(11). pii: E2260. doi: 10.3390/ijms18112260.

5.

Progressive modulation of the human olfactory bulb transcriptome during Alzheimer´s disease evolution: novel insights into the olfactory signaling across proteinopathies.

Lachen-Montes M, Zelaya MV, Segura V, Fernández-Irigoyen J, Santamaría E.

Oncotarget. 2017 May 23;8(41):69663-69679. doi: 10.18632/oncotarget.18193. eCollection 2017 Sep 19.

6.

Fluoxetine administration during adolescence attenuates cognitive and synaptic deficits in adult 3×TgAD mice.

Sun DS, Gao LF, Jin L, Wu H, Wang Q, Zhou Y, Fan S, Jiang X, Ke D, Lei H, Wang JZ, Liu GP.

Neuropharmacology. 2017 Nov;126:200-212. doi: 10.1016/j.neuropharm.2017.08.037. Epub 2017 Sep 11.

PMID:
28911966
7.

Association study of CREB1 and CBP genes with Alzheimer's disease in Han Chinese.

Tang W, Yang F, Lu W, Ni J, Zhang J, Tang W, Tang W, Zhang C.

Asia Pac Psychiatry. 2017 Sep;9(3). doi: 10.1111/appy.12274. No abstract available.

PMID:
28856841
8.

Ethanol-induced PGE2 up-regulates Aβ production through PKA/CREB signaling pathway.

Gabr AA, Lee HJ, Onphachanh X, Jung YH, Kim JS, Chae CW, Han HJ.

Biochim Biophys Acta. 2017 Nov;1863(11):2942-2953. doi: 10.1016/j.bbadis.2017.06.020. Epub 2017 Jun 28.

PMID:
28668332
9.

Cotinine improves visual recognition memory and decreases cortical Tau phosphorylation in the Tg6799 mice.

Grizzell JA, Patel S, Barreto GE, Echeverria V.

Prog Neuropsychopharmacol Biol Psychiatry. 2017 Aug 1;78:75-81. doi: 10.1016/j.pnpbp.2017.05.010. Epub 2017 May 20.

PMID:
28536070
10.

Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits.

Larson ME, Greimel SJ, Amar F, LaCroix M, Boyle G, Sherman MA, Schley H, Miel C, Schneider JA, Kayed R, Benfenati F, Lee MK, Bennett DA, Lesné SE.

Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):E4648-E4657. doi: 10.1073/pnas.1704698114. Epub 2017 May 22.

11.

Autophagy Activation Alleviates Amyloid-β-Induced Oxidative Stress, Apoptosis and Neurotoxicity in Human Neuroblastoma SH-SY5Y Cells.

Singh AK, Bissoyi A, Kashyap MP, Patra PK, Rizvi SI.

Neurotox Res. 2017 Oct;32(3):351-361. doi: 10.1007/s12640-017-9746-5. Epub 2017 May 8.

PMID:
28484969
12.

Intranasal Lactoferrin Enhances α-Secretase-Dependent Amyloid Precursor Protein Processing via the ERK1/2-CREB and HIF-1α Pathways in an Alzheimer's Disease Mouse Model.

Guo C, Yang ZH, Zhang S, Chai R, Xue H, Zhang YH, Li JY, Wang ZY.

Neuropsychopharmacology. 2017 Dec;42(13):2504-2515. doi: 10.1038/npp.2017.8. Epub 2017 Jan 12.

PMID:
28079060
13.

FFPM, a PDE4 inhibitor, reverses learning and memory deficits in APP/PS1 transgenic mice via cAMP/PKA/CREB signaling and anti-inflammatory effects.

Guo H, Cheng Y, Wang C, Wu J, Zou Z, Niu B, Yu H, Wang H, Xu J.

Neuropharmacology. 2017 Apr;116:260-269. doi: 10.1016/j.neuropharm.2017.01.004. Epub 2017 Jan 6.

PMID:
28065587
14.

Melatonin ameliorates amygdala-dependent emotional memory deficits in Tg2576 mice by up-regulating the CREB/c-Fos pathway.

Peng C, Hong X, Chen W, Zhang H, Tan L, Wang X, Ding Y, He J.

Neurosci Lett. 2017 Jan 18;638:76-82. doi: 10.1016/j.neulet.2016.11.066. Epub 2016 Dec 6.

PMID:
27939977
15.

CRTC1 Function During Memory Encoding Is Disrupted in Neurodegeneration.

Parra-Damas A, Chen M, Enriquez-Barreto L, Ortega L, Acosta S, Perna JC, Fullana MN, Aguilera J, Rodríguez-Alvarez J, Saura CA.

Biol Psychiatry. 2017 Jan 15;81(2):111-123. doi: 10.1016/j.biopsych.2016.06.025. Epub 2016 Jul 11.

PMID:
27587263
16.

TNFAIP1 contributes to the neurotoxicity induced by Aβ25-35 in Neuro2a cells.

Liu N, Yu Z, Xun Y, Li M, Peng X, Xiao Y, Hu X, Sun Y, Yang M, Gan S, Yuan S, Wang X, Xiang S, Zhang J.

BMC Neurosci. 2016 Jul 18;17(1):51. doi: 10.1186/s12868-016-0286-3.

17.

Desipramine improves depression-like behavior and working memory by up-regulating p-CREB in Alzheimer's disease associated mice.

Wang DD, Li J, Yu LP, Wu MN, Sun LN, Qi JS.

J Integr Neurosci. 2016 Jun;15(2):247-60. doi: 10.1142/S021963521650014X. Epub 2016 Jun 23.

PMID:
27338163
18.

Mixture of Peanut Skin Extract and Fish Oil Improves Memory in Mice via Modulation of Anti-Oxidative Stress and Regulation of BDNF/ERK/CREB Signaling Pathways.

Xiang L, Cao XL, Xing TY, Mori D, Tang RQ, Li J, Gao LJ, Qi JH.

Nutrients. 2016 Apr 28;8(5). pii: E256. doi: 10.3390/nu8050256.

19.

Dl-3-n-butylphthalide-induced upregulation of antioxidant defense is involved in the enhancement of cross talk between CREB and Nrf2 in an Alzheimer's disease mouse model.

Wang CY, Wang ZY, Xie JW, Wang T, Wang X, Xu Y, Cai JH.

Neurobiol Aging. 2016 Feb;38:32-46. doi: 10.1016/j.neurobiolaging.2015.10.024. Epub 2015 Nov 2.

PMID:
26827641
20.

Diminished CRE-Induced Plasticity is Linked to Memory Deficits in Familial Alzheimer's Disease Mice.

Bartolotti N, Segura L, Lazarov O.

J Alzheimers Dis. 2016;50(2):477-89. doi: 10.3233/JAD-150650.

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