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Items: 1 to 20 of 207


Evidence for benefit of statins to modify cognitive decline and risk in Alzheimer's disease.

Geifman N, Brinton RD, Kennedy RE, Schneider LS, Butte AJ.

Alzheimers Res Ther. 2017 Feb 17;9(1):10. doi: 10.1186/s13195-017-0237-y.


RImmPort: an R/Bioconductor package that enables ready-for-analysis immunology research data.

Shankar RD, Bhattacharya S, Jujjavarapu C, Andorf S, Wiser JA, Butte AJ.

Bioinformatics. 2017 Jan 5. pii: btw719. doi: 10.1093/bioinformatics/btw719. [Epub ahead of print]


Solving Immunology?

Vodovotz Y, Xia A, Read EL, Bassaganya-Riera J, Hafler DA, Sontag E, Wang J, Tsang JS, Day JD, Kleinstein SH, Butte AJ, Altman MC, Hammond R, Sealfon SC.

Trends Immunol. 2017 Feb;38(2):116-127. doi: 10.1016/ Review.


In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma.

Pessetto ZY, Chen B, Alturkmani H, Hyter S, Flynn CA, Baltezor M, Ma Y, Rosenthal HG, Neville KA, Weir SJ, Butte AJ, Godwin AK.

Oncotarget. 2017 Jan 17;8(3):4079-4095. doi: 10.18632/oncotarget.13385.


Integrating Clinical Phenotype and Gene Expression Data to Prioritize Novel Drug Uses.

Paik H, Chen B, Sirota M, Hadley D, Butte AJ.

CPT Pharmacometrics Syst Pharmacol. 2016 Nov;5(11):599-607. doi: 10.1002/psp4.12108.


It takes a genome to understand a village: Population scale precision medicine.

Butte AJ.

Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):12344-12346. No abstract available.


Defective Signaling in the JAK-STAT Pathway Tracks with Chronic Inflammation and Cardiovascular Risk in Aging Humans.

Shen-Orr SS, Furman D, Kidd BA, Hadad F, Lovelace P, Huang YW, Rosenberg-Hasson Y, Mackey S, Grisar FA, Pickman Y, Maecker HT, Chien YH, Dekker CL, Wu JC, Butte AJ, Davis MM.

Cell Syst. 2016 Oct 26;3(4):374-384.e4. doi: 10.1016/j.cels.2016.09.009.


Differential Phasing between Circadian Clocks in the Brain and Peripheral Organs in Humans.

Hughey JJ, Butte AJ.

J Biol Rhythms. 2016 Dec;31(6):588-597. doi: 10.1177/0748730416668049.


Digitally deconvolving the tumor microenvironment.

Aran D, Butte AJ.

Genome Biol. 2016 Aug 22;17(1):175. doi: 10.1186/s13059-016-1036-7.


Widespread parainflammation in human cancer.

Aran D, Lasry A, Zinger A, Biton M, Pikarsky E, Hellman A, Butte AJ, Ben-Neriah Y.

Genome Biol. 2016 Jul 8;17(1):145. doi: 10.1186/s13059-016-0995-z.


Identification of matrix metalloproteinase-12 as a candidate molecule for prevention and treatment of cardiometabolic disease.

Amor M, Moreno-Viedma V, Sarabi A, GrĂ¼n NG, Itariu B, Leitner L, Steiner I, Bilban M, Kodama K, Butte AJ, Staffler G, Zeyda M, Stulnig TM.

Mol Med. 2016 Jun 30;22. doi: 10.2119/molmed.2016.00068. [Epub ahead of print]


Microfluidic single-cell transcriptional analysis rationally identifies novel surface marker profiles to enhance cell-based therapies.

Rennert RC, Januszyk M, Sorkin M, Rodrigues M, Maan ZN, Duscher D, Whittam AJ, Kosaraju R, Chung MT, Paik K, Li AY, Findlay M, Glotzbach JP, Butte AJ, Gurtner GC.

Nat Commun. 2016 Jun 21;7:11945. doi: 10.1038/ncomms11945.


A patient-level data meta-analysis of standard-of-care treatments from eight prostate cancer clinical trials.

Geifman N, Butte AJ.

Sci Data. 2016 May 10;3:160027. doi: 10.1038/sdata.2016.27.


Cross-tissue Analysis of Gene and Protein Expression in Normal and Cancer Tissues.

Kosti I, Jain N, Aran D, Butte AJ, Sirota M.

Sci Rep. 2016 May 4;6:24799. doi: 10.1038/srep24799.


Constraints on Biological Mechanism from Disease Comorbidity Using Electronic Medical Records and Database of Genetic Variants.

Bagley SC, Sirota M, Chen R, Butte AJ, Altman RB.

PLoS Comput Biol. 2016 Apr 26;12(4):e1004885. doi: 10.1371/journal.pcbi.1004885.


Expression-Based Genome-Wide Association Study Links Vitamin D-Binding Protein With Autoantigenicity in Type 1 Diabetes.

Kodama K, Zhao Z, Toda K, Yip L, Fuhlbrigge R, Miao D, Fathman CG, Yamada S, Butte AJ, Yu L.

Diabetes. 2016 May;65(5):1341-9. doi: 10.2337/db15-1308.


Corrigendum: Systematic pan-cancer analysis of tumour purity.

Aran D, Sirota M, Butte AJ.

Nat Commun. 2016 Feb 5;7:10707. doi: 10.1038/ncomms10707. No abstract available.


ZeitZeiger: supervised learning for high-dimensional data from an oscillatory system.

Hughey JJ, Hastie T, Butte AJ.

Nucleic Acids Res. 2016 May 5;44(8):e80. doi: 10.1093/nar/gkw030.


Compendium of Immune Signatures Identifies Conserved and Species-Specific Biology in Response to Inflammation.

Godec J, Tan Y, Liberzon A, Tamayo P, Bhattacharya S, Butte AJ, Mesirov JP, Haining WN.

Immunity. 2016 Jan 19;44(1):194-206. doi: 10.1016/j.immuni.2015.12.006.

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