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Items: 1 to 20 of 352

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1.

Association of metals with the risk and clinical characteristics of Parkinson's disease.

Kim MJ, Oh SB, Kim J, Kim K, Ryu HS, Kim MS, Ayton S, Bush AI, Lee JY, Chung SJ.

Parkinsonism Relat Disord. 2018 May 28. pii: S1353-8020(18)30254-2. doi: 10.1016/j.parkreldis.2018.05.022. [Epub ahead of print]

PMID:
29891430
2.

Iron and Alzheimer's Disease: An Update on Emerging Mechanisms.

Lane DJR, Ayton S, Bush AI.

J Alzheimers Dis. 2018 May 26. doi: 10.3233/JAD-179944. [Epub ahead of print]

PMID:
29865061
3.

Glutaredoxins employ parallel monothiol-dithiol mechanisms to catalyze thiol-disulfide exchanges with protein disulfides.

Ukuwela AA, Bush AI, Wedd AG, Xiao Z.

Chem Sci. 2017 Dec 6;9(5):1173-1183. doi: 10.1039/c7sc04416j. eCollection 2018 Feb 7.

4.

Alzheimer's Disease: A Journey from Amyloid Peptides and Oxidative Stress, to Biomarker Technologies and Disease Prevention Strategies-Gains from AIBL and DIAN Cohort Studies.

Martins RN, Villemagne V, Sohrabi HR, Chatterjee P, Shah TM, Verdile G, Fraser P, Taddei K, Gupta VB, Rainey-Smith SR, Hone E, Pedrini S, Lim WL, Martins I, Frost S, Gupta S, O'Bryant S, Rembach A, Ames D, Ellis K, Fuller SJ, Brown B, Gardener SL, Fernando B, Bharadwaj P, Burnham S, Laws SM, Barron AM, Goozee K, Wahjoepramono EJ, Asih PR, Doecke JD, Salvado O, Bush AI, Rowe CC, Gandy SE, Masters CL.

J Alzheimers Dis. 2018;62(3):965-992. doi: 10.3233/JAD-171145.

5.

Metals and Alzheimer's Disease: How Far Have We Come in the Clinic?

Adlard PA, Bush AI.

J Alzheimers Dis. 2018;62(3):1369-1379. doi: 10.3233/JAD-170662.

6.

Ionophore and Biometal Modulation of P-glycoprotein Expression and Function in Human Brain Microvascular Endothelial Cells.

McInerney MP, Volitakis I, Bush AI, Banks WA, Short JL, Nicolazzo JA.

Pharm Res. 2018 Mar 5;35(4):83. doi: 10.1007/s11095-018-2377-6.

PMID:
29508078
7.

Novel Defense by Metallothionein Induction Against Cognitive Decline: From Amyloid β1-42-Induced Excess Zn2+ to Functional Zn2+ Deficiency.

Takeda A, Tamano H, Hashimoto W, Kobuchi S, Suzuki H, Murakami T, Tempaku M, Koike Y, Adlard PA, Bush AI.

Mol Neurobiol. 2018 Feb 19. doi: 10.1007/s12035-018-0948-5. [Epub ahead of print]

PMID:
29460269
8.

KIBRA is associated with accelerated cognitive decline and hippocampal atrophy in APOE ε4-positive cognitively normal adults with high Aβ-amyloid burden.

Porter T, Burnham SC, Doré V, Savage G, Bourgeat P, Begemann K, Milicic L, Ames D, Bush AI, Maruff P, Masters CL, Rowe CC, Rainey-Smith S, Martins RN, Groth D, Verdile G, Villemagne VL, Laws SM.

Sci Rep. 2018 Feb 1;8(1):2034. doi: 10.1038/s41598-018-20513-y.

9.

Iron as a therapeutic target for Parkinson's disease.

Moreau C, Duce JA, Rascol O, Devedjian JC, Berg D, Dexter D, Cabantchik ZI, Bush AI, Devos D; FAIRPARK-II study group.

Mov Disord. 2018 Apr;33(4):568-574. doi: 10.1002/mds.27275. Epub 2018 Jan 30. No abstract available.

PMID:
29380903
10.

What can predict and prevent the long-term use of benzodiazepines?

Hata T, Kanazawa T, Hamada T, Nishihara M, Bush AI, Yoneda H, Nakajima M, Katsumata T.

J Psychiatr Res. 2018 Feb;97:94-100. doi: 10.1016/j.jpsychires.2017.11.012. Epub 2017 Nov 24.

PMID:
29223863
11.

Concordance Between Cerebrospinal Fluid Biomarkers with Alzheimer's Disease Pathology Between Three Independent Assay Platforms.

Doecke JD, Rembach A, Villemagne VL, Varghese S, Rainey-Smith S, Sarros S, Evered LA, Fowler CJ, Pertile KK, Rumble RL, Trounson B, Taddei K, Laws SM, Macaulay SL, Bush AI, Ellis KA, Martins R, Ames D, Silbert B, Vanderstichele H, Masters CL, Darby DG, Li QX, Collins S; AIBL Research Group.

J Alzheimers Dis. 2018;61(1):169-183. doi: 10.3233/JAD-170128.

PMID:
29171991
12.

S-sulfocysteine/NMDA receptor-dependent signaling underlies neurodegeneration in molybdenum cofactor deficiency.

Kumar A, Dejanovic B, Hetsch F, Semtner M, Fusca D, Arjune S, Santamaria-Araujo JA, Winkelmann A, Ayton S, Bush AI, Kloppenburg P, Meier JC, Schwarz G, Belaidi AA.

J Clin Invest. 2017 Dec 1;127(12):4365-4378. doi: 10.1172/JCI89885. Epub 2017 Nov 6.

13.

A blood-based biomarker panel indicates IL-10 and IL-12/23p40 are jointly associated as predictors of β-amyloid load in an AD cohort.

Pedrini S, Gupta VB, Hone E, Doecke J, O'Bryant S, James I, Bush AI, Rowe CC, Villemagne VL, Ames D, Masters CL, Martins RN; AIBL Research Group.

Sci Rep. 2017 Oct 25;7(1):14057. doi: 10.1038/s41598-017-14020-9.

14.

Nanoscale Imaging Reveals Big Role for Iron in Alzheimer's Disease.

Ayton S, James SA, Bush AI.

Cell Chem Biol. 2017 Oct 19;24(10):1192-1194. doi: 10.1016/j.chembiol.2017.10.002.

PMID:
29053948
15.

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease.

Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, Oyagi A, Pagnussat GC, Park J, Ran Q, Rosenfeld CS, Salnikow K, Tang D, Torti FM, Torti SV, Toyokuni S, Woerpel KA, Zhang DD.

Cell. 2017 Oct 5;171(2):273-285. doi: 10.1016/j.cell.2017.09.021. Review.

PMID:
28985560
16.

Reduction potentials of protein disulfides and catalysis of glutathionylation and deglutathionylation by glutaredoxin enzymes.

Ukuwela AA, Bush AI, Wedd AG, Xiao Z.

Biochem J. 2017 Nov 9;474(22):3799-3815. doi: 10.1042/BCJ20170589.

PMID:
28963348
17.

Evidence that iron accelerates Alzheimer's pathology: a CSF biomarker study.

Ayton S, Diouf I, Bush AI; Alzheimer’s disease Neuroimaging Initiative.

J Neurol Neurosurg Psychiatry. 2018 May;89(5):456-460. doi: 10.1136/jnnp-2017-316551. Epub 2017 Sep 22.

PMID:
28939683
18.

Cerebral quantitative susceptibility mapping predicts amyloid-β-related cognitive decline.

Ayton S, Fazlollahi A, Bourgeat P, Raniga P, Ng A, Lim YY, Diouf I, Farquharson S, Fripp J, Ames D, Doecke J, Desmond P, Ordidge R, Masters CL, Rowe CC, Maruff P, Villemagne VL; Australian Imaging Biomarkers and Lifestyle (AIBL) Research Group, Salvado O, Bush AI.

Brain. 2017 Aug 1;140(8):2112-2119. doi: 10.1093/brain/awx137.

PMID:
28899019
19.

Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis.

Masaldan S, Clatworthy SAS, Gamell C, Meggyesy PM, Rigopoulos AT, Haupt S, Haupt Y, Denoyer D, Adlard PA, Bush AI, Cater MA.

Redox Biol. 2018 Apr;14:100-115. doi: 10.1016/j.redox.2017.08.015. Epub 2017 Sep 1.

20.

Tau-mediated iron export prevents ferroptotic damage after ischemic stroke.

Tuo QZ, Lei P, Jackman KA, Li XL, Xiong H, Li XL, Liuyang ZY, Roisman L, Zhang ST, Ayton S, Wang Q, Crouch PJ, Ganio K, Wang XC, Pei L, Adlard PA, Lu YM, Cappai R, Wang JZ, Liu R, Bush AI.

Mol Psychiatry. 2017 Nov;22(11):1520-1530. doi: 10.1038/mp.2017.171. Epub 2017 Sep 8.

PMID:
28886009

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