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2012 3
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2016 5
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61 results

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Page 1
The impact of treatment with avacopan on health-related quality of life in antineutrophil cytoplasmic antibody-associated vasculitis: a post-hoc analysis of data from the ADVOCATE trial.
Strand V, Jayne DRW, Horomanski A, Yue H, Bekker P, Merkel PA; ADVOCATE Study Group. Strand V, et al. Lancet Rheumatol. 2023 Aug;5(8):e451-e460. doi: 10.1016/S2665-9913(23)00092-9. Epub 2023 Jul 24. Lancet Rheumatol. 2023. PMID: 38251577 Clinical Trial.
We analysed summary scores and individual domain scores for the prespecified health-related quality of life outcomes from ADVOCATE, which were evaluated at weeks 26 and 52 by use of the Medical Outcomes Survey 36-Item Short Form Health Survey (SF-36) version 2, the EuroQol 5-Dime …
We analysed summary scores and individual domain scores for the prespecified health-related quality of life outcomes from ADVOCATE, which we …
Incremental benefits of circumferential minimally invasive surgery for increasingly frail patients with adult spinal deformity.
Passias PG, Tretiakov PS, Nunley PD, Wang MY, Park P, Kanter AS, Okonkwo DO, Eastlack RK, Mundis GM, Chou D, Agarwal N, Fessler RG, Uribe JS, Anand N, Than KD, Brusko G, Fu KM, Turner JD, Le VP, Line BG, Ames CP, Smith JS, Shaffrey CI, Hart RA, Burton D, Lafage R, Lafage V, Schwab F, Bess S, Mummaneni PV. Passias PG, et al. J Neurosurg Spine. 2023 Apr 21;39(2):168-174. doi: 10.3171/2023.2.SPINE221278. Print 2023 Aug 1. J Neurosurg Spine. 2023. PMID: 37086158
Adjusted analysis also revealed that compared to open patients, increasingly frail patients in the cMIS group were also more likely to demonstrate greater improvement in 1- and 2-year postoperative scores for the Oswestry Disability Index, SRS-36 (total), EQ-5D and SF-36 ( …
Adjusted analysis also revealed that compared to open patients, increasingly frail patients in the cMIS group were also more likely to demon …
Increased MYBL2 expression in aggressive hormone-sensitive prostate cancer.
Yoshikawa Y, Stopsack KH, Wang XV, Chen YH, Mazzu YZ, Burton F, Chakraborty G, Rajanala SH, Hirani R, Nandakumar S, Lee GM, Frank D, Davicioni E, Liu G, Carducci MA, Azuma H, Kantoff PW, Sweeney CJ. Yoshikawa Y, et al. Mol Oncol. 2022 Dec;16(22):3994-4010. doi: 10.1002/1878-0261.13314. Epub 2022 Oct 2. Mol Oncol. 2022. PMID: 36087093 Free PMC article.
Loss of the histone demethylase KDM5D (lysine-specific demethylase 5D) leads to in vitro resistance of prostate cancer cells to androgen deprivation therapy (ADT) with and without docetaxel. ...
Loss of the histone demethylase KDM5D (lysine-specific demethylase 5D) leads to in vitro resistance of prostate cancer cells to andro …
Daily Step Count and Postprandial Fat Metabolism.
Burton HM, Coyle EF. Burton HM, et al. Med Sci Sports Exerc. 2021 Feb 1;53(2):333-340. doi: 10.1249/MSS.0000000000002486. Med Sci Sports Exerc. 2021. PMID: 33105387 Clinical Trial.
POSNOC-POsitive Sentinel NOde: adjuvant therapy alone versus adjuvant therapy plus Clearance or axillary radiotherapy: a randomised controlled trial of axillary treatment in women with early-stage breast cancer who have metastases in one or two sentinel nodes.
Goyal A, Mann GB, Fallowfield L, Duley L, Reed M, Dodwell D, Coleman RE, Fakis A, Newcombe R, Jenkins V, Whitham D, Childs M, Whynes D, Keeley V, Ellis I, Fairbrother P, Sadiq S, Monson K, Montgomery A, Tan W, Vale L, Homer T, Badger H, Haines RH, Lewis M, Megias D, Nabi Z, Singh P, Caraman A, Miles E; POSNOC Trialists. Goyal A, et al. BMJ Open. 2021 Dec 2;11(12):e054365. doi: 10.1136/bmjopen-2021-054365. BMJ Open. 2021. PMID: 34857578 Free PMC article. Clinical Trial.
Secondary outcomes are arm morbidity assessed by Lymphoedema and Breast Cancer Questionnaire and QuickDASH questionnaires; quality of life and anxiety as assessed with FACT B+4 and State/Trait Anxiety Inventory questionnaires, respectively; other oncological outcomes; economic ev …
Secondary outcomes are arm morbidity assessed by Lymphoedema and Breast Cancer Questionnaire and QuickDASH questionnaires; quality of life a …
Biologics for chronic rhinosinusitis.
Chong LY, Piromchai P, Sharp S, Snidvongs K, Philpott C, Hopkins C, Burton MJ. Chong LY, et al. Cochrane Database Syst Rev. 2020 Feb 27;2(2):CD013513. doi: 10.1002/14651858.CD013513.pub2. Cochrane Database Syst Rev. 2020. PMID: 32102112 Free PMC article. Updated.
Change in the extent of disease using the Lund Mackay computerised tomography (CT) score (0 to 24, higher = worse) was -7.00 (95% CI -9.61 to -4.39; 3 studies; 784 participants; high certainty), a large effect favouring the dupilumab group. The EQ-5D visual analogue scale …
Change in the extent of disease using the Lund Mackay computerised tomography (CT) score (0 to 24, higher = worse) was -7.00 (95% CI -9.61 t …
Surgical outcomes in rigid versus flexible cervical deformities.
Protopsaltis TS, Stekas N, Smith JS, Soroceanu A, Lafage R, Daniels AH, Kim HJ, Passias PG, Mundis GM, Klineberg EO, Hamilton DK, Gupta M, Lafage V, Hart RA, Schwab F, Burton DC, Bess S, Shaffrey CI, Ames CP. Protopsaltis TS, et al. J Neurosurg Spine. 2021 Feb 12;34(5):716-724. doi: 10.3171/2020.8.SPINE191185. J Neurosurg Spine. 2021. PMID: 33578386
Both rigid and flexible CD patients reported significant improvements from baseline to 1 year according to the numeric rating scale for the neck (-2.4 and -2.7, respectively), Neck Disability Index (-8.4 and -13.3, respectively), modified Japanese Orthopaedic Association score (0 …
Both rigid and flexible CD patients reported significant improvements from baseline to 1 year according to the numeric rating scale for the …
The Relationship Between Improvements in Myelopathy and Sagittal Realignment in Cervical Deformity Surgery Outcomes.
Passias PG, Horn SR, Bortz CA, Ramachandran S, Burton DC, Protopsaltis T, Lafage R, Lafage V, Diebo BG, Poorman GW, Segreto FA, Smith JS, Ames C, Shaffrey CI, Kim HJ, Neuman B, Daniels AH, Soroceanu A, Klineberg E; International Spine Study Group (ISSG). Passias PG, et al. Spine (Phila Pa 1976). 2018 Aug;43(16):1117-1124. doi: 10.1097/BRS.0000000000002610. Spine (Phila Pa 1976). 2018. PMID: 29462071

There were no differences in decompression, baseline alignment, mJOA, EQ-5D, or NDI between groups. Patients who improved only in myelopathy showed significant differences in baseline-1Y EQ-5D (baseline: 0.74, 1 yr:0.83, P < 0.001). One-year C2-S1 sagittal vertic

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There were no differences in decompression, baseline alignment, mJOA, EQ-5D, or NDI between groups. Patients who improved only in mye …
61 results