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Items: 1 to 20 of 28

1.

Deubiquitylating enzymes in receptor endocytosis and trafficking.

McCann AP, Scott CJ, Van Schaeybroeck S, Burrows JF.

Biochem J. 2016 Dec 15;473(24):4507-4525. Review.

PMID:
27941029
2.

Unlocking the Doors to Patient Satisfaction in Pediatric Orthopaedics.

Peng FB, Burrows JF, Shirley ED, Rosen P.

J Pediatr Orthop. 2016 Jul 20. [Epub ahead of print]

PMID:
27442213
3.

Factors Influencing Patient Experience in Pediatric Neurology.

Singh SC, Sheth RD, Burrows JF, Rosen P.

Pediatr Neurol. 2016 Jul;60:37-41. doi: 10.1016/j.pediatrneurol.2016.04.002.

PMID:
27238409
4.

Extracellular cathepsin S and intracellular caspase 1 activation are surrogate biomarkers of particulate-induced lysosomal disruption in macrophages.

Hughes CS, Colhoun LM, Bains BK, Kilgour JD, Burden RE, Burrows JF, Lavelle EC, Gilmore BF, Scott CJ.

Part Fibre Toxicol. 2016 Apr 23;13:19. doi: 10.1186/s12989-016-0129-5.

PMID:
27108091
5.

Physician Engagement in the Transformation of the Pediatric Patient Experience.

Rosen P, Burrows JF, Greenspan JS.

J Pediatr. 2016 Feb;169:4-5. doi: 10.1016/j.jpeds.2015.11.023. No abstract available.

PMID:
26810098
6.

Targeting Siglecs with a sialic acid-decorated nanoparticle abrogates inflammation.

Spence S, Greene MK, Fay F, Hams E, Saunders SP, Hamid U, Fitzgerald M, Beck J, Bains BK, Smyth P, Themistou E, Small DM, Schmid D, O'Kane CM, Fitzgerald DC, Abdelghany SM, Johnston JA, Fallon PG, Burrows JF, McAuley DF, Kissenpfennig A, Scott CJ.

Sci Transl Med. 2015 Sep 2;7(303):303ra140. doi: 10.1126/scitranslmed.aab3459.

PMID:
26333936
7.

USP17 is required for clathrin mediated endocytosis of epidermal growth factor receptor.

Jaworski J, de la Vega M, Fletcher SJ, McFarlane C, Greene MK, Smyth AW, Van Schaeybroeck S, Johnston JA, Scott CJ, Rappoport JZ, Burrows JF.

Oncotarget. 2014 Aug 30;5(16):6964-75.

PMID:
25026282
8.

A novel RCE1 isoform is required for H-Ras plasma membrane localization and is regulated by USP17.

Jaworski J, Govender U, McFarlane C, de la Vega M, Greene MK, Rawlings ND, Johnston JA, Scott CJ, Burrows JF.

Biochem J. 2014 Jan 15;457(2):289-300. doi: 10.1042/BJ20131213.

PMID:
24134311
9.

A highly potent and specific MET therapeutic protein antagonist with both ligand-dependent and ligand-independent activity.

Olwill SA, Joffroy C, Gille H, Vigna E, Matschiner G, Allersdorfer A, Lunde BM, Jaworski J, Burrows JF, Chiriaco C, Christian HJ, Hülsmeyer M, Trentmann S, Jensen K, Hohlbaum AM, Audoly L.

Mol Cancer Ther. 2013 Nov;12(11):2459-71. doi: 10.1158/1535-7163.MCT-13-0318.

PMID:
24002935
10.

Cathepsin S from both tumor and tumor-associated cells promote cancer growth and neovascularization.

Small DM, Burden RE, Jaworski J, Hegarty SM, Spence S, Burrows JF, McFarlane C, Kissenpfennig A, McCarthy HO, Johnston JA, Walker B, Scott CJ.

Int J Cancer. 2013 Nov;133(9):2102-12. doi: 10.1002/ijc.28238.

PMID:
23629809
11.

Enhanced antitumor activity of the photosensitizer meso-Tetra(N-methyl-4-pyridyl) porphine tetra tosylate through encapsulation in antibody-targeted chitosan/alginate nanoparticles.

Abdelghany SM, Schmid D, Deacon J, Jaworski J, Fay F, McLaughlin KM, Gormley JA, Burrows JF, Longley DB, Donnelly RF, Scott CJ.

Biomacromolecules. 2013 Feb 11;14(2):302-10. doi: 10.1021/bm301858a.

PMID:
23327610
12.

Regulation of cellular responses by deubiquitinating enzymes: an update.

Burrows JF, Johnston JA.

Front Biosci (Landmark Ed). 2012 Jan 1;17:1184-200. Review.

PMID:
22201797
13.

Ubiquitination: Added complexity in Ras and Rho family GTPase function.

de la Vega M, Burrows JF, Johnston JA.

Small GTPases. 2011 Jul;2(4):192-201.

PMID:
22145091
14.

The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.

de la Vega M, Kelvin AA, Dunican DJ, McFarlane C, Burrows JF, Jaworski J, Stevenson NJ, Dib K, Rappoport JZ, Scott CJ, Long A, Johnston JA.

Nat Commun. 2011 Mar 29;2:259. doi: 10.1038/ncomms1243.

PMID:
21448158
15.

The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster.

Burrows JF, Scott CJ, Johnston JA.

BMC Genomics. 2010 Apr 19;11:250. doi: 10.1186/1471-2164-11-250.

PMID:
20403174
16.

The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression.

McFarlane C, Kelvin AA, de la Vega M, Govender U, Scott CJ, Burrows JF, Johnston JA.

Cancer Res. 2010 Apr 15;70(8):3329-39. doi: 10.1158/0008-5472.CAN-09-4152.

PMID:
20388806
17.

The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected.

de la Vega M, Burrows JF, McFarlane C, Govender U, Scott CJ, Johnston JA.

J Biol Chem. 2010 Apr 16;285(16):12028-36. doi: 10.1074/jbc.M109.081448.

PMID:
20147298
18.

Siglec-E is up-regulated and phosphorylated following lipopolysaccharide stimulation in order to limit TLR-driven cytokine production.

Boyd CR, Orr SJ, Spence S, Burrows JF, Elliott J, Carroll HP, Brennan K, Ní Gabhann J, Coulter WA, Jones C, Crocker PR, Johnston JA, Jefferies CA.

J Immunol. 2009 Dec 15;183(12):7703-9. doi: 10.4049/jimmunol.0902780. Erratum in: J Immunol. 2010 Feb 1;184(3):1655. Jones, Claire [added]; Crocker, Paul R [added].

PMID:
19933851
19.

USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity.

Burrows JF, Kelvin AA, McFarlane C, Burden RE, McGrattan MJ, De la Vega M, Govender U, Quinn DJ, Dib K, Gadina M, Scott CJ, Johnston JA.

J Biol Chem. 2009 Apr 3;284(14):9587-95. doi: 10.1074/jbc.M807216200.

PMID:
19188362
20.

Respiratory syncytial virus NS1 protein degrades STAT2 by using the Elongin-Cullin E3 ligase.

Elliott J, Lynch OT, Suessmuth Y, Qian P, Boyd CR, Burrows JF, Buick R, Stevenson NJ, Touzelet O, Gadina M, Power UF, Johnston JA.

J Virol. 2007 Apr;81(7):3428-36.

PMID:
17251292

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