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Items: 18

1.

Biochemical Characterization of Glutamate Racemase-A New Candidate Drug Target against Burkholderia cenocepacia Infections.

Israyilova A, Buroni S, Forneris F, Scoffone VC, Shixaliyev NQ, Riccardi G, Chiarelli LR.

PLoS One. 2016 Nov 29;11(11):e0167350. doi: 10.1371/journal.pone.0167350. eCollection 2016.

2.

Discovery of new diketopiperazines inhibiting Burkholderia cenocepacia quorum sensing in vitro and in vivo.

Scoffone VC, Chiarelli LR, Makarov V, Brackman G, Israyilova A, Azzalin A, Forneris F, Riabova O, Savina S, Coenye T, Riccardi G, Buroni S.

Sci Rep. 2016 Sep 1;6:32487. doi: 10.1038/srep32487.

3.

Efflux-mediated resistance to a benzothiadiazol derivative effective against Burkholderia cenocepacia.

Scoffone VC, Ryabova O, Makarov V, Iadarola P, Fumagalli M, Fondi M, Fani R, De Rossi E, Riccardi G, Buroni S.

Front Microbiol. 2015 Aug 5;6:815. doi: 10.3389/fmicb.2015.00815. eCollection 2015.

4.

Differential roles of RND efflux pumps in antimicrobial drug resistance of sessile and planktonic Burkholderia cenocepacia cells.

Buroni S, Matthijs N, Spadaro F, Van Acker H, Scoffone VC, Pasca MR, Riccardi G, Coenye T.

Antimicrob Agents Chemother. 2014 Dec;58(12):7424-9. doi: 10.1128/AAC.03800-14. Epub 2014 Sep 29.

5.

Mechanism of resistance to an antitubercular 2-thiopyridine derivative that is also active against Burkholderia cenocepacia.

Scoffone VC, Spadaro F, Udine C, Makarov V, Fondi M, Fani R, De Rossi E, Riccardi G, Buroni S.

Antimicrob Agents Chemother. 2014;58(4):2415-7. doi: 10.1128/AAC.02438-13. Epub 2014 Jan 6.

6.

Phenotypic and genotypic characterisation of Burkholderia cenocepacia J2315 mutants affected in homoserine lactone and diffusible signal factor-based quorum sensing systems suggests interplay between both types of systems.

Udine C, Brackman G, Bazzini S, Buroni S, Van Acker H, Pasca MR, Riccardi G, Coenye T.

PLoS One. 2013;8(1):e55112. doi: 10.1371/journal.pone.0055112. Epub 2013 Jan 28.

7.

Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis.

Neres J, Pojer F, Molteni E, Chiarelli LR, Dhar N, Boy-Röttger S, Buroni S, Fullam E, Degiacomi G, Lucarelli AP, Read RJ, Zanoni G, Edmondson DE, De Rossi E, Pasca MR, McKinney JD, Dyson PJ, Riccardi G, Mattevi A, Cole ST, Binda C.

Sci Transl Med. 2012 Sep 5;4(150):150ra121. doi: 10.1126/scitranslmed.3004395.

8.

Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis.

Ribeiro AL, Degiacomi G, Ewann F, Buroni S, Incandela ML, Chiarelli LR, Mori G, Kim J, Contreras-Dominguez M, Park YS, Han SJ, Brodin P, Valentini G, Rizzi M, Riccardi G, Pasca MR.

PLoS One. 2011;6(11):e26675. doi: 10.1371/journal.pone.0026675. Epub 2011 Nov 1.

9.

MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212.

La Rosa V, Poce G, Canseco JO, Buroni S, Pasca MR, Biava M, Raju RM, Porretta GC, Alfonso S, Battilocchio C, Javid B, Sorrentino F, Ioerger TR, Sacchettini JC, Manetti F, Botta M, De Logu A, Rubin EJ, De Rossi E.

Antimicrob Agents Chemother. 2012 Jan;56(1):324-31. doi: 10.1128/AAC.05270-11. Epub 2011 Oct 24.

10.

Deciphering the role of RND efflux transporters in Burkholderia cenocepacia.

Bazzini S, Udine C, Sass A, Pasca MR, Longo F, Emiliani G, Fondi M, Perrin E, Decorosi F, Viti C, Giovannetti L, Leoni L, Fani R, Riccardi G, Mahenthiralingam E, Buroni S.

PLoS One. 2011 Apr 19;6(4):e18902. doi: 10.1371/journal.pone.0018902.

11.

Molecular mechanisms of chlorhexidine tolerance in Burkholderia cenocepacia biofilms.

Coenye T, Van Acker H, Peeters E, Sass A, Buroni S, Riccardi G, Mahenthiralingam E.

Antimicrob Agents Chemother. 2011 May;55(5):1912-9. doi: 10.1128/AAC.01571-10. Epub 2011 Feb 28.

12.

Mycobacterium tuberculosis phosphoribosylpyrophosphate synthetase: biochemical features of a crucial enzyme for mycobacterial cell wall biosynthesis.

Lucarelli AP, Buroni S, Pasca MR, Rizzi M, Cavagnino A, Valentini G, Riccardi G, Chiarelli LR.

PLoS One. 2010 Nov 15;5(11):e15494. doi: 10.1371/journal.pone.0015494.

13.

Exploring the HME and HAE1 efflux systems in the genus Burkholderia.

Perrin E, Fondi M, Papaleo MC, Maida I, Buroni S, Pasca MR, Riccardi G, Fani R.

BMC Evol Biol. 2010 Jun 3;10:164. doi: 10.1186/1471-2148-10-164.

14.

Structural plasticity and distinct drug-binding modes of LfrR, a mycobacterial efflux pump regulator.

Bellinzoni M, Buroni S, Schaeffer F, Riccardi G, De Rossi E, Alzari PM.

J Bacteriol. 2009 Dec;191(24):7531-7. doi: 10.1128/JB.00631-09. Epub 2009 Oct 9.

15.

Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepacia in intrinsic antibiotic resistance.

Buroni S, Pasca MR, Flannagan RS, Bazzini S, Milano A, Bertani I, Venturi V, Valvano MA, Riccardi G.

BMC Microbiol. 2009 Sep 17;9:200. doi: 10.1186/1471-2180-9-200.

16.

Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis.

Makarov V, Manina G, Mikusova K, Möllmann U, Ryabova O, Saint-Joanis B, Dhar N, Pasca MR, Buroni S, Lucarelli AP, Milano A, De Rossi E, Belanova M, Bobovska A, Dianiskova P, Kordulakova J, Sala C, Fullam E, Schneider P, McKinney JD, Brodin P, Christophe T, Waddell S, Butcher P, Albrethsen J, Rosenkrands I, Brosch R, Nandi V, Bharath S, Gaonkar S, Shandil RK, Balasubramanian V, Balganesh T, Tyagi S, Grosset J, Riccardi G, Cole ST.

Science. 2009 May 8;324(5928):801-4. doi: 10.1126/science.1171583. Epub 2009 Mar 19.

17.

LfrR is a repressor that regulates expression of the efflux pump LfrA in Mycobacterium smegmatis.

Buroni S, Manina G, Guglierame P, Pasca MR, Riccardi G, De Rossi E.

Antimicrob Agents Chemother. 2006 Dec;50(12):4044-52. Epub 2006 Oct 16.

18.

Efflux pump genes of the resistance-nodulation-division family in Burkholderia cenocepacia genome.

Guglierame P, Pasca MR, De Rossi E, Buroni S, Arrigo P, Manina G, Riccardi G.

BMC Microbiol. 2006 Jul 20;6:66.

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