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Items: 1 to 20 of 333

1.

Effective "activated PI3Kδ syndrome"-targeted therapy with the PI3Kδ inhibitor leniolisib.

Rao VK, Webster S, Dalm VASH, Šedivá A, van Hagen PM, Holland S, Rosenzweig SD, Christ AD, Sloth B, Cabanski M, Joshi AD, de Buck S, Doucet J, Guerini D, Kalis C, Pylvaenaeinen I, Soldermann N, Kashyap A, Uzel G, Lenardo MJ, Patel DD, Lucas CL, Burkhart C.

Blood. 2017 Nov 23;130(21):2307-2316. doi: 10.1182/blood-2017-08-801191. Epub 2017 Sep 29.

PMID:
28972011
2.

Discovery of CDZ173 (Leniolisib), Representing a Structurally Novel Class of PI3K Delta-Selective Inhibitors.

Hoegenauer K, Soldermann N, Zécri F, Strang RS, Graveleau N, Wolf RM, Cooke NG, Smith AB, Hollingworth GJ, Blanz J, Gutmann S, Rummel G, Littlewood-Evans A, Burkhart C.

ACS Med Chem Lett. 2017 Aug 25;8(9):975-980. doi: 10.1021/acsmedchemlett.7b00293. eCollection 2017 Sep 14.

PMID:
28947947
3.

The Internet for patient education on atopic dermatitis: Friend or foe?

Corcimaru A, Morrell DS, Burkhart CN.

J Am Acad Dermatol. 2017 Jun;76(6):1197-1198. doi: 10.1016/j.jaad.2017.01.054. No abstract available.

PMID:
28522047
4.

Associations Between Impaired Cerebral Blood Flow Autoregulation, Cerebral Oxygenation, and Biomarkers of Brain Injury and Postoperative Cognitive Dysfunction in Elderly Patients After Major Noncardiac Surgery.

Goettel N, Burkhart CS, Rossi A, Cabella BC, Berres M, Monsch AU, Czosnyka M, Steiner LA.

Anesth Analg. 2017 Mar;124(3):934-942. doi: 10.1213/ANE.0000000000001803.

PMID:
28151820
5.

Mind the gap! Automated concept map feedback supports students in writing cohesive explanations.

Lachner A, Burkhart C, Nückles M.

J Exp Psychol Appl. 2017 Mar;23(1):29-46. doi: 10.1037/xap0000111. Epub 2017 Jan 2.

PMID:
28045279
6.

Discovery of novel pyrrolidineoxy-substituted heteroaromatics as potent and selective PI3K delta inhibitors with improved physicochemical properties.

Hoegenauer K, Soldermann N, Hebach C, Hollingworth GJ, Lewis I, von Matt A, Smith AB, Wolf RM, Wilcken R, Haasen D, Burkhart C, Zécri F.

Bioorg Med Chem Lett. 2016 Dec 1;26(23):5657-5662. doi: 10.1016/j.bmcl.2016.10.069. Epub 2016 Oct 27.

PMID:
27816514
7.

Preclinical Validation of a Single-Treatment Infusion Modality That Can Eradicate Extremity Melanomas.

Kim M, Neznanov N, Wilfong CD, Fleyshman DI, Purmal AA, Haderski G, Stanhope-Baker P, Burkhart CA, Gurova KV, Gudkov AV, Skitzki JJ.

Cancer Res. 2016 Nov 15;76(22):6620-6630. doi: 10.1158/0008-5472.CAN-15-2764. Epub 2016 Sep 28.

8.

Discovery and Pharmacological Characterization of Novel Quinazoline-Based PI3K Delta-Selective Inhibitors.

Hoegenauer K, Soldermann N, Stauffer F, Furet P, Graveleau N, Smith AB, Hebach C, Hollingworth GJ, Lewis I, Gutmann S, Rummel G, Knapp M, Wolf RM, Blanz J, Feifel R, Burkhart C, Zécri F.

ACS Med Chem Lett. 2016 Jun 2;7(8):762-7. doi: 10.1021/acsmedchemlett.6b00119. eCollection 2016 Aug 11.

9.

Anticancer drug candidate CBL0137, which inhibits histone chaperone FACT, is efficacious in preclinical orthotopic models of temozolomide-responsive and -resistant glioblastoma.

Barone TA, Burkhart CA, Safina A, Haderski G, Gurova KV, Purmal AA, Gudkov AV, Plunkett RJ.

Neuro Oncol. 2017 Feb 1;19(2):186-196. doi: 10.1093/neuonc/now141.

PMID:
27370399
10.

Leveraging a Sturge-Weber Gene Discovery: An Agenda for Future Research.

Comi AM, Sahin M, Hammill A, Kaplan EH, Juhász C, North P, Ball KL, Levin AV, Cohen B, Morris J, Lo W, Roach ES; 2015 Sturge-Weber Syndrome Research Workshop.

Pediatr Neurol. 2016 May;58:12-24. doi: 10.1016/j.pediatrneurol.2015.11.009. Epub 2016 Mar 16.

11.

Predicting the occurrence of major adverse cardiac events within 30 days of a vascular surgery: an empirical comparison of the minimum p value method and ROC curve approach using individual patient data meta-analysis.

Vanniyasingam T, Rodseth RN, Lurati Buse GA, Bolliger D, Burkhart CS, Cuthbertson BH, Gibson SC, Mahla E, Leibowitz DW, Biccard BM, Thabane L.

Springerplus. 2016 Mar 9;5:304. doi: 10.1186/s40064-016-1936-8. eCollection 2016.

12.

Differentiation of latex allergy from irritant contact dermatitis.

Burkhart C, Schloemer J, Zirwas M.

Cutis. 2015 Dec;96(6):369-71, 401.

PMID:
26761937
13.

Planarized Intramolecular Charge Transfer: A Concept for Fluorophores with both Large Stokes Shifts and High Fluorescence Quantum Yields.

Haberhauer G, Gleiter R, Burkhart C.

Chemistry. 2016 Jan 18;22(3):971-8. doi: 10.1002/chem.201503927. Epub 2015 Dec 16.

PMID:
26670768
14.

Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma.

Carter DR, Murray J, Cheung BB, Gamble L, Koach J, Tsang J, Sutton S, Kalla H, Syed S, Gifford AJ, Issaeva N, Biktasova A, Atmadibrata B, Sun Y, Sokolowski N, Ling D, Kim PY, Webber H, Clark A, Ruhle M, Liu B, Oberthuer A, Fischer M, Byrne J, Saletta F, Thwe le M, Purmal A, Haderski G, Burkhart C, Speleman F, De Preter K, Beckers A, Ziegler DS, Liu T, Gurova KV, Gudkov AV, Norris MD, Haber M, Marshall GM.

Sci Transl Med. 2015 Nov 4;7(312):312ra176. doi: 10.1126/scitranslmed.aab1803.

PMID:
26537256
15.

Microbiome and pediatric atopic dermatitis.

Powers CE, McShane DB, Gilligan PH, Burkhart CN, Morrell DS.

J Dermatol. 2015 Dec;42(12):1137-42. doi: 10.1111/1346-8138.13072. Epub 2015 Sep 21. Review.

PMID:
26388516
16.

Monitoring of cerebral blood flow autoregulation in adults undergoing sevoflurane anesthesia: a prospective cohort study of two age groups.

Goettel N, Patet C, Rossi A, Burkhart CS, Czosnyka M, Strebel SP, Steiner LA.

J Clin Monit Comput. 2016 Jun;30(3):255-64. doi: 10.1007/s10877-015-9754-z. Epub 2015 Aug 19.

PMID:
26285741
17.

Predictors of the variability in neuromuscular block duration following succinylcholine: A prospective, observational study.

Dell-Kuster S, Levano S, Burkhart CS, Lelais F, Zemp A, Schobinger E, Hampl K, Kindler C, Girard T.

Eur J Anaesthesiol. 2015 Oct;32(10):687-96. doi: 10.1097/EJA.0000000000000308.

PMID:
26213905
18.

Acne therapeutics: a closer look at benzoyl peroxide.

Mohammad TF, Burkhart CG.

Skinmed. 2015 Mar-Apr;13(2):94-6. No abstract available.

PMID:
26137733
19.

Is the current model for acne pathogenesis backwards?

Metiko B, Brooks K, Burkhart CG, Burkhart CN, Morrell D.

J Am Acad Dermatol. 2015 Jun;72(6):e167. doi: 10.1016/j.jaad.2015.01.041. No abstract available.

PMID:
25981026
20.

Adverse effects of acne medications: recognition and management.

Oudenhoven MD, Kinney MA, McShane DB, Burkhart CN, Morrell DS.

Am J Clin Dermatol. 2015 Aug;16(4):231-242. doi: 10.1007/s40257-015-0127-7. Review.

PMID:
25896771

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