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Items: 1 to 20 of 142

1.

Mapping the pathway and dynamics of bestatin inhibition of the Plasmodium falciparum M1 aminopeptidase, PfA-M1.

Yang W, Riley B, Lei X, Porebski BT, Kass I, Buckle AM, McGowan S.

ChemMedChem. 2018 Oct 14. doi: 10.1002/cmdc.201800563. [Epub ahead of print]

PMID:
30318749
2.

Catalytic diversity and cell wall binding repeats in the phage encoded endolysins.

Broendum SS, Buckle AM, McGowan S.

Mol Microbiol. 2018 Sep 19. doi: 10.1111/mmi.14134. [Epub ahead of print] Review.

PMID:
30230642
3.

Structural Capacitance in Protein Evolution and Human Diseases.

Li C, Clark LVT, Zhang R, Porebski BT, McCoey JM, Borg NA, Webb GI, Kass I, Buckle M, Song J, Woolfson A, Buckle AM.

J Mol Biol. 2018 Sep 14;430(18 Pt B):3200-3217. doi: 10.1016/j.jmb.2018.06.051. Epub 2018 Jul 3.

PMID:
30111491
4.

Substrate Locking Promotes Dimer-Dimer Docking of an Enzyme Antibiotic Target.

Atkinson SC, Dogovski C, Wood K, Griffin MDW, Gorman MA, Hor L, Reboul CF, Buckle AM, Wuttke J, Parker MW, Dobson RCJ, Perugini MA.

Structure. 2018 Jul 3;26(7):948-959.e5. doi: 10.1016/j.str.2018.04.014. Epub 2018 May 24.

PMID:
29804823
5.

Previously Hidden Dynamics at the TCR-Peptide-MHC Interface Revealed.

Fodor J, Riley BT, Borg NA, Buckle AM.

J Immunol. 2018 Jun 15;200(12):4134-4145. doi: 10.4049/jimmunol.1800315. Epub 2018 May 4.

PMID:
29728507
6.

Recognition by host nuclear transport proteins drives disorder-to-order transition in Hendra virus V.

Atkinson SC, Audsley MD, Lieu KG, Marsh GA, Thomas DR, Heaton SM, Paxman JJ, Wagstaff KM, Buckle AM, Moseley GW, Jans DA, Borg NA.

Sci Rep. 2018 Jan 10;8(1):358. doi: 10.1038/s41598-017-18742-8.

7.

Laboratory evolution of protein conformational dynamics.

Campbell EC, Correy GJ, Mabbitt PD, Buckle AM, Tokuriki N, Jackson CJ.

Curr Opin Struct Biol. 2018 Jun;50:49-57. doi: 10.1016/j.sbi.2017.09.005. Epub 2017 Nov 8. Review.

PMID:
29120734
8.

Generation of AMBER force field parameters for zinc centres of M1 and M17 family aminopeptidases.

Yang W, Riley BT, Lei X, Porebski BT, Kass I, Buckle AM, McGowan S.

J Biomol Struct Dyn. 2018 Aug;36(10):2595-2604. doi: 10.1080/07391102.2017.1364669. Epub 2017 Aug 28.

PMID:
28782419
9.

REFOLDdb: a new and sustainable gateway to experimental protocols for protein refolding.

Mizutani H, Sugawara H, Buckle AM, Sangawa T, Miyazono KI, Ohtsuka J, Nagata K, Shojima T, Nosaki S, Xu Y, Wang D, Hu X, Tanokura M, Yura K.

BMC Struct Biol. 2017 Apr 24;17(1):4. doi: 10.1186/s12900-017-0074-z.

10.

The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger.

Keightley MC, Carradice DP, Layton JE, Pase L, Bertrand JY, Wittig JG, Dakic A, Badrock AP, Cole NJ, Traver D, Nutt SL, McCoey J, Buckle AM, Heath JK, Lieschke GJ.

Nat Commun. 2017 Apr 6;8:14911. doi: 10.1038/ncomms14911.

11.

Structural reconstruction of protein ancestry.

Rouet R, Langley DB, Schofield P, Christie M, Roome B, Porebski BT, Buckle AM, Clifton BE, Jackson CJ, Stock D, Christ D.

Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3897-3902. doi: 10.1073/pnas.1613477114. Epub 2017 Mar 29.

12.

Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics.

Riley BT, Ilyichova O, Costa MG, Porebski BT, de Veer SJ, Swedberg JE, Kass I, Harris JM, Hoke DE, Buckle AM.

Sci Rep. 2016 Oct 21;6:35385. doi: 10.1038/srep35385.

13.

The role of protein dynamics in the evolution of new enzyme function.

Campbell E, Kaltenbach M, Correy GJ, Carr PD, Porebski BT, Livingstone EK, Afriat-Jurnou L, Buckle AM, Weik M, Hollfelder F, Tokuriki N, Jackson CJ.

Nat Chem Biol. 2016 Nov;12(11):944-950. doi: 10.1038/nchembio.2175. Epub 2016 Sep 12.

PMID:
27618189
14.

Smoothing a rugged protein folding landscape by sequence-based redesign.

Porebski BT, Keleher S, Hollins JJ, Nickson AA, Marijanovic EM, Borg NA, Costa MG, Pearce MA, Dai W, Zhu L, Irving JA, Hoke DE, Kass I, Whisstock JC, Bottomley SP, Webb GI, McGowan S, Buckle AM.

Sci Rep. 2016 Sep 26;6:33958. doi: 10.1038/srep33958.

15.

Circumventing the stability-function trade-off in an engineered FN3 domain.

Porebski BT, Conroy PJ, Drinkwater N, Schofield P, Vazquez-Lombardi R, Hunter MR, Hoke DE, Christ D, McGowan S, Buckle AM.

Protein Eng Des Sel. 2016 Aug 29. [Epub ahead of print]

16.

Consensus protein design.

Porebski BT, Buckle AM.

Protein Eng Des Sel. 2016 Jul;29(7):245-51. doi: 10.1093/protein/gzw015. Epub 2016 Jun 5. Review.

17.

PolyQ 2.0: an improved version of PolyQ, a database of human polyglutamine proteins.

Li C, Nagel J, Androulakis S, Lupton CJ, Song J, Buckle AM.

Database (Oxford). 2016 May 17;2016. pii: baw050. doi: 10.1093/database/baw050. Print 2016. No abstract available.

18.

KinetochoreDB: a comprehensive online resource for the kinetochore and its related proteins.

Li C, Androulakis S, Buckle AM, Song J.

Database (Oxford). 2016 Mar 17;2016. pii: baw019. doi: 10.1093/database/baw019. Print 2016.

19.

PolyQ 2.0: an improved version of PolyQ, a database of human polyglutamine proteins.

Li C, Nagel J, Androulakis S, Song J, Buckle AM.

Database (Oxford). 2016 Mar 15;2016. pii: baw021. doi: 10.1093/database/baw021. Print 2016. Erratum in: Database (Oxford). 2016;2016. pii: baw050. doi: 10.1093/database/baw050.

20.

A colostrum trypsin inhibitor gene expressed in the Cape fur seal mammary gland during lactation.

Pharo EA, Cane KN, McCoey J, Buckle AM, Oosthuizen WH, Guinet C, Arnould JP.

Gene. 2016 Mar 1;578(1):7-16. doi: 10.1016/j.gene.2015.11.042. Epub 2015 Nov 27.

PMID:
26639991

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