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Items: 1 to 20 of 160

1.

The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates.

Mazur NI, Higgins D, Nunes MC, Melero JA, Langedijk AC, Horsley N, Buchholz UJ, Openshaw PJ, McLellan JS, Englund JA, Mejias A, Karron RA, Simões EA, Knezevic I, Ramilo O, Piedra PA, Chu HY, Falsey AR, Nair H, Kragten-Tabatabaie L, Greenough A, Baraldi E, Papadopoulos NG, Vekemans J, Polack FP, Powell M, Satav A, Walsh EE, Stein RT, Graham BS, Bont LJ; Respiratory Syncytial Virus Network (ReSViNET) Foundation.

Lancet Infect Dis. 2018 Jun 15. pii: S1473-3099(18)30292-5. doi: 10.1016/S1473-3099(18)30292-5. [Epub ahead of print] Review.

PMID:
29914800
2.

Differential responses by human respiratory epithelial cell lines to respiratory syncytial virus reflect distinct patterns of infection control.

Hillyer P, Shepard R, Uehling M, Krenz M, Sheikh F, Thayer KR, Huang L, Yan L, Panda D, Luongo C, Buchholz UJ, Collins PL, Donnelly RP, Rabin RL.

J Virol. 2018 May 16. pii: JVI.02202-17. doi: 10.1128/JVI.02202-17. [Epub ahead of print]

PMID:
29769339
3.

Live Respiratory Syncytial Virus (RSV) Vaccine Candidate Containing Stabilized Temperature-Sensitivity Mutations Is Highly Attenuated in RSV-Seronegative Infants and Children.

Buchholz UJ, Cunningham CK, Muresan P, Gnanashanmugam D, Sato P, Siberry GK, Rexroad V, Valentine M, Perlowski C, Schappell E, Thumar B, Luongo C, Barr E, Aziz M, Yogev R, Spector SA, Collins PL, McFarland EJ, Karron RA; International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) P1114 Study Team.

J Infect Dis. 2018 Apr 11;217(9):1338-1346. doi: 10.1093/infdis/jiy066.

PMID:
29509929
4.

Live-Attenuated Respiratory Syncytial Virus Vaccine Candidate With Deletion of RNA Synthesis Regulatory Protein M2-2 is Highly Immunogenic in Children.

McFarland EJ, Karron RA, Muresan P, Cunningham CK, Valentine ME, Perlowski C, Thumar B, Gnanashanmugam D, Siberry GK, Schappell E, Barr E, Rexroad V, Yogev R, Spector SA, Aziz M, Patel N, Cielo M, Luongo C, Collins PL, Buchholz UJ; International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) 2000 Study Team.

J Infect Dis. 2018 Apr 11;217(9):1347-1355. doi: 10.1093/infdis/jiy040.

PMID:
29509911
5.

Estimates of global seasonal influenza-associated respiratory mortality: a modelling study.

Iuliano AD, Roguski KM, Chang HH, Muscatello DJ, Palekar R, Tempia S, Cohen C, Gran JM, Schanzer D, Cowling BJ, Wu P, Kyncl J, Ang LW, Park M, Redlberger-Fritz M, Yu H, Espenhain L, Krishnan A, Emukule G, van Asten L, Pereira da Silva S, Aungkulanon S, Buchholz U, Widdowson MA, Bresee JS; Global Seasonal Influenza-associated Mortality Collaborator Network.

Lancet. 2018 Mar 31;391(10127):1285-1300. doi: 10.1016/S0140-6736(17)33293-2. Epub 2017 Dec 14. Erratum in: Lancet. 2018 Jan 19;:.

PMID:
29248255
6.

Multicolor Stimulated Emission Depletion (STED) Microscopy to Generate High-resolution Images of Respiratory Syncytial Virus Particles and Infected Cells.

Mehedi M, Smelkinson M, Kabat J, Ganesan S, Collins PL, Buchholz UJ.

Bio Protoc. 2017 Sep 5;7(17). pii: e2543. doi: 10.21769/BioProtoc.2543.

7.

A novel host factor for human respiratory syncytial virus.

Mehedi M, Collins PL, Buchholz UJ.

Commun Integr Biol. 2017 May 8;10(3):e1319025. doi: 10.1080/19420889.2017.1319025. eCollection 2017.

8.

Evaluation of a Live Attenuated Human Metapneumovirus Vaccine in Adults and Children.

Karron RA, San Mateo J, Wanionek K, Collins PL, Buchholz UJ.

J Pediatric Infect Dis Soc. 2018 Feb 19;7(1):86-89. doi: 10.1093/jpids/pix006.

PMID:
28444226
9.

Is the impact of childhood influenza vaccination less than expected: a transmission modelling study.

Weidemann F, Remschmidt C, Buda S, Buchholz U, Ultsch B, Wichmann O.

BMC Infect Dis. 2017 Apr 11;17(1):258. doi: 10.1186/s12879-017-2344-6.

10.

Attenuated Human Parainfluenza Virus Type 1 Expressing Ebola Virus Glycoprotein GP Administered Intranasally Is Immunogenic in African Green Monkeys.

Lingemann M, Liu X, Surman S, Liang B, Herbert R, Hackenberg AD, Buchholz UJ, Collins PL, Munir S.

J Virol. 2017 Apr 28;91(10). pii: e02469-16. doi: 10.1128/JVI.02469-16. Print 2017 May 15.

11.

Respiratory syncytial virus infection induces a subset of types I and III interferons in human dendritic cells.

Hillyer P, Mane VP, Chen A, Dos Santos MB, Schramm LM, Shepard RE, Luongo C, Le Nouën C, Huang L, Yan L, Buchholz UJ, Jubin RG, Collins PL, Rabin RL.

Virology. 2017 Apr;504:63-72. doi: 10.1016/j.virol.2017.01.017. Epub 2017 Jan 31.

12.

Genetic stability of genome-scale deoptimized RNA virus vaccine candidates under selective pressure.

Le Nouën C, McCarty T, Brown M, Smith ML, Lleras R, Dolan MA, Mehedi M, Yang L, Luongo C, Liang B, Munir S, DiNapoli JM, Mueller S, Wimmer E, Collins PL, Buchholz UJ.

Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E386-E395. doi: 10.1073/pnas.1619242114. Epub 2017 Jan 3.

13.

Actin-Related Protein 2 (ARP2) and Virus-Induced Filopodia Facilitate Human Respiratory Syncytial Virus Spread.

Mehedi M, McCarty T, Martin SE, Le Nouën C, Buehler E, Chen YC, Smelkinson M, Ganesan S, Fischer ER, Brock LG, Liang B, Munir S, Collins PL, Buchholz UJ.

PLoS Pathog. 2016 Dec 7;12(12):e1006062. doi: 10.1371/journal.ppat.1006062. eCollection 2016 Dec.

14.

Estimation of influenza-attributable medically attended acute respiratory illness by influenza type/subtype and age, Germany, 2001/02-2014/15.

An der Heiden M, Buchholz U.

Influenza Other Respir Viruses. 2017 Mar;11(2):110-121. doi: 10.1111/irv.12434. Epub 2016 Nov 18.

15.

Human metapneumovirus Induces Reorganization of the Actin Cytoskeleton for Direct Cell-to-Cell Spread.

El Najjar F, Cifuentes-Muñoz N, Chen J, Zhu H, Buchholz UJ, Moncman CL, Dutch RE.

PLoS Pathog. 2016 Sep 28;12(9):e1005922. doi: 10.1371/journal.ppat.1005922. eCollection 2016 Sep.

16.

I-MOVE multicentre case-control study 2010/11 to 2014/15: Is there within-season waning of influenza type/subtype vaccine effectiveness with increasing time since vaccination?

Kissling E, Nunes B, Robertson C, Valenciano M, Reuss A, Larrauri A, Cohen JM, Oroszi B, Rizzo C, Machado A, Pitigoi D, Domegan L, Paradowska-Stankiewicz I, Buchholz U, Gherasim A, Daviaud I, Horváth JK, Bella A, Lupulescu E, O Donnell J, Korczyńska M, Moren A; I-MOVE case–control study team.

Euro Surveill. 2016 Apr 21;21(16). doi: 10.2807/1560-7917.ES.2016.21.16.30201.

17.

[Influenza pandemic deaths in Germany from 1918 to 2009. Estimates based on literature and own calculations].

Buchholz U, Buda S, Reuß A, Haas W, Uphoff H.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2016 Apr;59(4):523-36. doi: 10.1007/s00103-016-2324-9. Review. German.

PMID:
26984565
18.

Evaluation of a Live-Attenuated Human Parainfluenza Type 1 Vaccine in Adults and Children.

Karron RA, San Mateo J, Thumar B, Schaap-Nutt A, Buchholz UJ, Schmidt AC, Bartlett EJ, Murphy BR, Collins PL.

J Pediatric Infect Dis Soc. 2015 Dec;4(4):e143-6. doi: 10.1093/jpids/piu104. Epub 2014 Nov 12.

19.

A gene deletion that up-regulates viral gene expression yields an attenuated RSV vaccine with improved antibody responses in children.

Karron RA, Luongo C, Thumar B, Loehr KM, Englund JA, Collins PL, Buchholz UJ.

Sci Transl Med. 2015 Nov 4;7(312):312ra175. doi: 10.1126/scitranslmed.aac8463.

PMID:
26537255
20.

Low-level Circulation of Enterovirus D68-Associated Acute Respiratory Infections, Germany, 2014.

Reiche J, Böttcher S, Diedrich S, Buchholz U, Buda S, Haas W, Schweiger B, Wolff T.

Emerg Infect Dis. 2015 May;21(5):837-41. doi: 10.3201/eid2105.141900.

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