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Items: 1 to 20 of 32


Fibrosis independent atrial fibrillation in older patients is driven by substrate leukocyte infiltration: diagnostic and prognostic implications to patients undergoing cardiac surgery.

Aguiar CM, Gawdat K, Legere S, Marshall J, Hassan A, Kienesberger PC, Pulinilkunnil T, Castonguay M, Brunt KR, Legare JF.

J Transl Med. 2019 Dec 10;17(1):413. doi: 10.1186/s12967-019-02162-5.


Splenic blood-flow response following myocardial infarction in rat.

Ruggiero SA, Huber JS, Murrant CL, Brunt KR, Simpson JA.

Can J Physiol Pharmacol. 2018 Nov;96(11):1060-1068. doi: 10.1139/cjpp-2018-0134. Epub 2018 Aug 13.


Getting to the heart of myofibroblast differentiation: implications for scleraxis in ECM remodeling and therapeutic targeting.

Eadie AL, Titus AJ, Brunt KR.

Am J Physiol Heart Circ Physiol. 2018 Nov 1;315(5):H1232-H1235. doi: 10.1152/ajpheart.00381.2018. Epub 2018 Jun 29. No abstract available.


Pathophysiological Mapping of Experimental Heart Failure: Left and Right Ventricular Remodeling in Transverse Aortic Constriction Is Temporally, Kinetically and Structurally Distinct.

Platt MJ, Huber JS, Romanova N, Brunt KR, Simpson JA.

Front Physiol. 2018 May 15;9:472. doi: 10.3389/fphys.2018.00472. eCollection 2018.


A Comparison and Calibration of a Wrist-Worn Blood Pressure Monitor for Patient Management: Assessing the Reliability of Innovative Blood Pressure Devices.

Melville S, Teskey R, Philip S, Simpson JA, Lutchmedial S, Brunt KR.

J Med Internet Res. 2018 Apr 25;20(4):e111. doi: 10.2196/jmir.8009.


Moderate and severe hypoxia elicit divergent effects on cardiovascular function and physiological rhythms.

Allwood MA, Edgett BA, Eadie AL, Huber JS, Romanova N, Millar PJ, Brunt KR, Simpson JA.

J Physiol. 2018 Aug;596(15):3391-3410. doi: 10.1113/JP275945. Epub 2018 May 13.


Red blood cell antibody-induced anemia causes differential degrees of tissue hypoxia in kidney and brain.

Mistry N, Mazer CD, Sled JG, Lazarus AH, Cahill LS, Solish M, Zhou YQ, Romanova N, Hare AGM, Doctor A, Fisher JA, Brunt KR, Simpson JA, Hare GMT.

Am J Physiol Regul Integr Comp Physiol. 2018 Apr 1;314(4):R611-R622. doi: 10.1152/ajpregu.00182.2017. Epub 2018 Jan 10.


Lysophosphatidic acid receptor mRNA levels in heart and white adipose tissue are associated with obesity in mice and humans.

Brown A, Hossain I, Perez LJ, Nzirorera C, Tozer K, D'Souza K, Trivedi PC, Aguiar C, Yip AM, Shea J, Brunt KR, Legare JF, Hassan A, Pulinilkunnil T, Kienesberger PC.

PLoS One. 2017 Dec 13;12(12):e0189402. doi: 10.1371/journal.pone.0189402. eCollection 2017.


Pulmonary Flow as an Improved Method for Determining Cardiac Output in Mice after Myocardial Infarction.

Platt MJ, Huber JS, Brunt KR, Simpson JA.

J Am Soc Echocardiogr. 2017 Jun;30(6):612-623.e1. doi: 10.1016/j.echo.2017.02.008.


Central-acting therapeutics alleviate respiratory weakness caused by heart failure-induced ventilatory overdrive.

Foster AJ, Platt MJ, Huber JS, Eadie AL, Arkell AM, Romanova N, Wright DC, Gillis TE, Murrant CL, Brunt KR, Simpson JA.

Sci Transl Med. 2017 May 17;9(390). pii: eaag1303. doi: 10.1126/scitranslmed.aag1303.


Changes in Circulating Monocyte Subsets (CD16 Expression) and Neutrophil-to-Lymphocyte Ratio Observed in Patients Undergoing Cardiac Surgery.

Gawdat K, Legere S, Wong C, Myers T, Marshall JS, Hassan A, Brunt KR, Kienesberger PC, Pulinilkunnil T, Legare JF.

Front Cardiovasc Med. 2017 Mar 15;4:12. doi: 10.3389/fcvm.2017.00012. eCollection 2017.


Assessment of hypoxia and TNF-alpha response by a vector with HRE and NF-kappaB response elements.

Chen Z, Eadie AL, Hall SR, Ballantyne L, Ademidun D, Tse MY, Pang SC, Melo LG, Ward CA, Brunt KR.

Front Biosci (Schol Ed). 2017 Jan 1;9:46-54.


Glucolipotoxicity diminishes cardiomyocyte TFEB and inhibits lysosomal autophagy during obesity and diabetes.

Trivedi PC, Bartlett JJ, Perez LJ, Brunt KR, Legare JF, Hassan A, Kienesberger PC, Pulinilkunnil T.

Biochim Biophys Acta. 2016 Dec;1861(12 Pt A):1893-1910. doi: 10.1016/j.bbalip.2016.09.004. Epub 2016 Sep 9.


Translating calcified aortic valve disease to the bench - Use of 3D matrices in the development of future treatment strategies.

Madhu MN, Aguiar C, Hassan A, Brunt KR.

J Mol Cell Cardiol. 2016 Sep;98:58-61. doi: 10.1016/j.yjmcc.2016.06.062. Epub 2016 Jun 23. No abstract available.


"Fibroblast" pharmacotherapy - Advancing the next generation of therapeutics for clinical cardiology.

Eadie AL, Simpson JA, Brunt KR.

J Mol Cell Cardiol. 2016 May;94:176-179. doi: 10.1016/j.yjmcc.2016.03.018. Epub 2016 Apr 6. No abstract available.


Novel ZnO hollow-nanocarriers containing paclitaxel targeting folate-receptors in a malignant pH-microenvironment for effective monitoring and promoting breast tumor regression.

Puvvada N, Rajput S, Kumar BNP, Sarkar S, Konar S, Brunt KR, Rao RR, Mazumdar A, Das SK, Basu R, Fisher PB, Mandal M, Pathak A.

Sci Rep. 2015 Jul 6;5:11760. doi: 10.1038/srep11760.


Wilms' tumor 1 (re)activation in evidence for both epicardial progenitor and endothelial cells for cardiovascular regeneration.

Aguiar C, Brunt KR.

J Mol Cell Cardiol. 2015 Jul;84:112-5. doi: 10.1016/j.yjmcc.2015.04.001. Epub 2015 Apr 9. No abstract available.


Lennie: a smartphone application with novel implications for the management of animal colonies.

Allwood MA, Griffith D, Allen C, Reed J, Mahmoud QH, Brunt KR, Simpson JA.

Lab Anim. 2015 Jul;49(3):258-62. doi: 10.1177/0023677215570990. Epub 2015 Feb 4.


Holiday reading. Diving into the ice bucket challenge.

Adisesh A, Melville S, Pulinilkunnil T, Lutchmedial S, Brunt KR.

CMAJ. 2014 Dec 9;186(18):1404-5. doi: 10.1503/cmaj.141241. No abstract available.


Heme oxygenase-1 overexpression exacerbates heart failure with aging and pressure overload but is protective against isoproterenol-induced cardiomyopathy in mice.

Allwood MA, Kinobe RT, Ballantyne L, Romanova N, Melo LG, Ward CA, Brunt KR, Simpson JA.

Cardiovasc Pathol. 2014 Jul-Aug;23(4):231-7. doi: 10.1016/j.carpath.2014.03.007. Epub 2014 Apr 5.


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