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Items: 1 to 20 of 68


Local delivery of siRNA-loaded calcium phosphate nanoparticles abates pulmonary inflammation.

Frede A, Neuhaus B, Knuschke T, Wadwa M, Kollenda S, Klopfleisch R, Hansen W, Buer J, Bruder D, Epple M, Westendorf AM.

Nanomedicine. 2017 Nov;13(8):2395-2403. doi: 10.1016/j.nano.2017.08.001. Epub 2017 Aug 8.


Chronic lung inflammation primes humoral immunity and augments antipneumococcal resistance.

Boehme JD, Stegemann-Koniszewski S, Autengruber A, Peters N, Wissing J, Jänsch L, Jeron A, Bruder D.

Sci Rep. 2017 Jul 10;7(1):4972. doi: 10.1038/s41598-017-05212-4.


IL-33: a jack of all trades in the orchestration of respiratory antibacterial immunity.

Boehme JD, Bruder D.

Cell Mol Immunol. 2017 Jul 10. doi: 10.1038/cmi.2017.53. [Epub ahead of print] No abstract available.


c-REL and IκBNS Govern Common and Independent Steps of Regulatory T Cell Development from Novel CD122-Expressing Pre-Precursors.

Schuster M, Plaza-Sirvent C, Matthies AM, Heise U, Jeron A, Bruder D, Visekruna A, Huehn J, Schmitz I.

J Immunol. 2017 Aug 1;199(3):920-930. doi: 10.4049/jimmunol.1600877. Epub 2017 Jun 26.


Targeted antigen delivery to dendritic cells elicits robust antiviral T cell-mediated immunity in the liver.

Volckmar J, Gereke M, Ebensen T, Riese P, Philipsen L, Lienenklaus S, Wohlleber D, Klopfleisch R, Stegemann-Koniszewski S, Müller AJ, Gruber AD, Knolle P, Guzman CA, Bruder D.

Sci Rep. 2017 Mar 7;7:43985. doi: 10.1038/srep43985.


A Mouse Model of Post-Stroke Pneumonia Induced by Intra-Tracheal Inoculation with Streptococcus pneumoniae.

Mracsko E, Stegemann-Koniszewski S, Na SY, Dalpke A, Bruder D, Lasitschka F, Veltkamp R.

Cerebrovasc Dis. 2017;43(3-4):99-109. doi: 10.1159/000452136. Epub 2017 Jan 4.


Hierarchical effects of pro-inflammatory cytokines on the post-influenza susceptibility to pneumococcal coinfection.

Duvigneau S, Sharma-Chawla N, Boianelli A, Stegemann-Koniszewski S, Nguyen VK, Bruder D, Hernandez-Vargas EA.

Sci Rep. 2016 Nov 22;6:37045. doi: 10.1038/srep37045.


Soluble CD200 Correlates With Interleukin-6 Levels in Sera of COPD Patients: Potential Implication of the CD200/CD200R Axis in the Disease Course.

Sakthivel P, Breithaupt A, Gereke M, Copland DA, Schulz C, Gruber AD, Dick AD, Schreiber J, Bruder D.

Lung. 2017 Feb;195(1):59-68. doi: 10.1007/s00408-016-9962-4. Epub 2016 Nov 18.


A cell culture-derived whole virus influenza A vaccine based on magnetic sulfated cellulose particles confers protection in mice against lethal influenza A virus infection.

Pieler MM, Frentzel S, Bruder D, Wolff MW, Reichl U.

Vaccine. 2016 Dec 7;34(50):6367-6374. doi: 10.1016/j.vaccine.2016.10.041. Epub 2016 Nov 2.


Mechanism of granuloma formation in sarcoidosis.

Sakthivel P, Bruder D.

Curr Opin Hematol. 2017 Jan;24(1):59-65. Review.


Influenza A Virus Infection Predisposes Hosts to Secondary Infection with Different Streptococcus pneumoniae Serotypes with Similar Outcome but Serotype-Specific Manifestation.

Sharma-Chawla N, Sender V, Kershaw O, Gruber AD, Volckmar J, Henriques-Normark B, Stegemann-Koniszewski S, Bruder D.

Infect Immun. 2016 Nov 18;84(12):3445-3457. Print 2016 Dec.


ADAP plays a pivotal role in CD4+ T cell activation but is only marginally involved in CD8+ T cell activation, differentiation, and immunity to pathogens.

Parzmair GP, Gereke M, Haberkorn O, Annemann M, Podlasly L, Kliche S, Reinhold A, Schraven B, Bruder D.

J Leukoc Biol. 2017 Feb;101(2):407-419. doi: 10.1189/jlb.1A0216-090RR. Epub 2016 Sep 7.


Oseltamivir PK/PD Modeling and Simulation to Evaluate Treatment Strategies against Influenza-Pneumococcus Coinfection.

Boianelli A, Sharma-Chawla N, Bruder D, Hernandez-Vargas EA.

Front Cell Infect Microbiol. 2016 Jun 14;6:60. doi: 10.3389/fcimb.2016.00060. eCollection 2016.


Alveolar Type II Epithelial Cells Contribute to the Anti-Influenza A Virus Response in the Lung by Integrating Pathogen- and Microenvironment-Derived Signals.

Stegemann-Koniszewski S, Jeron A, Gereke M, Geffers R, Kröger A, Gunzer M, Bruder D.

MBio. 2016 May 3;7(3). pii: e00276-16. doi: 10.1128/mBio.00276-16.


Abscisic Acid: A Phytohormone and Mammalian Cytokine as Novel Pharmacon with Potential for Future Development into Clinical Applications.

Sakthivel P, Sharma N, Klahn P, Gereke M, Bruder D.

Curr Med Chem. 2016;23(15):1549-70. Review.


ImmunoPET/MR imaging allows specific detection of Aspergillus fumigatus lung infection in vivo.

Rolle AM, Hasenberg M, Thornton CR, Solouk-Saran D, Männ L, Weski J, Maurer A, Fischer E, Spycher PR, Schibli R, Boschetti F, Stegemann-Koniszewski S, Bruder D, Severin GW, Autenrieth SE, Krappmann S, Davies G, Pichler BJ, Gunzer M, Wiehr S.

Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):E1026-33. doi: 10.1073/pnas.1518836113. Epub 2016 Jan 19.


Modeling Influenza Virus Infection: A Roadmap for Influenza Research.

Boianelli A, Nguyen VK, Ebensen T, Schulze K, Wilk E, Sharma N, Stegemann-Koniszewski S, Bruder D, Toapanta FR, Guzmán CA, Meyer-Hermann M, Hernandez-Vargas EA.

Viruses. 2015 Oct 12;7(10):5274-304. doi: 10.3390/v7102875. Review.


Erratum to: Morphological and Functional Alterations of Alveolar Macrophages in a Murine Model of Chronic Inflammatory Lung Disease.

Boehme JD, Pietkiewicz S, Lavrik I, Jeron A, Bruder D.

Lung. 2015 Dec;193(6):955. doi: 10.1007/s00408-015-9812-9. No abstract available.


Morphological and Functional Alterations of Alveolar Macrophages in a Murine Model of Chronic Inflammatory Lung Disease.

Désirée Boehme J, Pietkiewicz S, Lavrik I, Jeron A, Bruder D.

Lung. 2015 Dec;193(6):947-53. doi: 10.1007/s00408-015-9797-4. Epub 2015 Aug 30. Erratum in: Lung. 2015 Dec;193(6):955.

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