Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 162

1.

Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer's mouse model.

Choi SH, Bylykbashi E, Chatila ZK, Lee SW, Pulli B, Clemenson GD, Kim E, Rompala A, Oram MK, Asselin C, Aronson J, Zhang C, Miller SJ, Lesinski A, Chen JW, Kim DY, van Praag H, Spiegelman BM, Gage FH, Tanzi RE.

Science. 2018 Sep 7;361(6406). pii: eaan8821. doi: 10.1126/science.aan8821.

PMID:
30190379
2.

Brown Adipose Tissue Controls Skeletal Muscle Function via the Secretion of Myostatin.

Kong X, Yao T, Zhou P, Kazak L, Tenen D, Lyubetskaya A, Dawes BA, Tsai L, Kahn BB, Spiegelman BM, Liu T, Rosen ED.

Cell Metab. 2018 Jul 25. pii: S1550-4131(18)30447-9. doi: 10.1016/j.cmet.2018.07.004. [Epub ahead of print]

PMID:
30078553
3.

Ablation of PM20D1 reveals N-acyl amino acid control of metabolism and nociception.

Long JZ, Roche AM, Berdan CA, Louie SM, Roberts AJ, Svensson KJ, Dou FY, Bateman LA, Mina AI, Deng Z, Jedrychowski MP, Lin H, Kamenecka TM, Asara JM, Griffin PR, Banks AS, Nomura DK, Spiegelman BM.

Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6937-E6945. doi: 10.1073/pnas.1803389115. Epub 2018 Jul 2.

4.

Discovery of Hydrolysis-Resistant Isoindoline N-Acyl Amino Acid Analogues that Stimulate Mitochondrial Respiration.

Lin H, Long JZ, Roche AM, Svensson KJ, Dou FY, Chang MR, Strutzenberg T, Ruiz C, Cameron MD, Novick SJ, Berdan CA, Louie SM, Nomura DK, Spiegelman BM, Griffin PR, Kamenecka TM.

J Med Chem. 2018 Apr 12;61(7):3224-3230. doi: 10.1021/acs.jmedchem.8b00029. Epub 2018 Mar 22.

PMID:
29533650
5.

Noncanonical agonist PPARγ ligands modulate the response to DNA damage and sensitize cancer cells to cytotoxic chemotherapy.

Khandekar MJ, Banks AS, Laznik-Bogoslavski D, White JP, Choi JH, Kazak L, Lo JC, Cohen P, Wong KK, Kamenecka TM, Griffin PR, Spiegelman BM.

Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):561-566. doi: 10.1073/pnas.1717776115. Epub 2018 Jan 2.

6.

Crosstalk between KCNK3-Mediated Ion Current and Adrenergic Signaling Regulates Adipose Thermogenesis and Obesity.

Chen Y, Zeng X, Huang X, Serag S, Woolf CJ, Spiegelman BM.

Cell. 2017 Nov 2;171(4):836-848.e13. doi: 10.1016/j.cell.2017.09.015. Epub 2017 Oct 5.

PMID:
28988768
7.

Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity.

Kazak L, Chouchani ET, Lu GZ, Jedrychowski MP, Bare CJ, Mina AI, Kumari M, Zhang S, Vuckovic I, Laznik-Bogoslavski D, Dzeja P, Banks AS, Rosen ED, Spiegelman BM.

Cell Metab. 2017 Oct 3;26(4):693. doi: 10.1016/j.cmet.2017.09.007. No abstract available.

8.

Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity.

Kazak L, Chouchani ET, Lu GZ, Jedrychowski MP, Bare CJ, Mina AI, Kumari M, Zhang S, Vuckovic I, Laznik-Bogoslavski D, Dzeja P, Banks AS, Rosen ED, Spiegelman BM.

Cell Metab. 2017 Oct 3;26(4):660-671.e3. doi: 10.1016/j.cmet.2017.08.009. Epub 2017 Aug 24. Erratum in: Cell Metab. 2017 Oct 3;26(4):693.

PMID:
28844881
9.

Mitochondrial reactive oxygen species and adipose tissue thermogenesis: Bridging physiology and mechanisms.

Chouchani ET, Kazak L, Spiegelman BM.

J Biol Chem. 2017 Oct 13;292(41):16810-16816. doi: 10.1074/jbc.R117.789628. Epub 2017 Aug 24. Review.

PMID:
28842500
10.

UCP1 deficiency causes brown fat respiratory chain depletion and sensitizes mitochondria to calcium overload-induced dysfunction.

Kazak L, Chouchani ET, Stavrovskaya IG, Lu GZ, Jedrychowski MP, Egan DF, Kumari M, Kong X, Erickson BK, Szpyt J, Rosen ED, Murphy MP, Kristal BS, Gygi SP, Spiegelman BM.

Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):7981-7986. doi: 10.1073/pnas.1705406114. Epub 2017 Jun 19.

11.

Do Adipocytes Emerge from Mural Progenitors?

Vishvanath L, Long JZ, Spiegelman BM, Gupta RK.

Cell Stem Cell. 2017 May 4;20(5):585-586. doi: 10.1016/j.stem.2017.03.013.

12.

CACHEXIA & BROWN FAT: A BURNING ISSUE IN CANCER.

Kir S, Spiegelman BM.

Trends Cancer. 2016 Sep;2(9):461-463. doi: 10.1016/j.trecan.2016.07.005.

13.

Mitochondrial Patch Clamp of Beige Adipocytes Reveals UCP1-Positive and UCP1-Negative Cells Both Exhibiting Futile Creatine Cycling.

Bertholet AM, Kazak L, Chouchani ET, Bogaczyńska MG, Paranjpe I, Wainwright GL, Bétourné A, Kajimura S, Spiegelman BM, Kirichok Y.

Cell Metab. 2017 Apr 4;25(4):811-822.e4. doi: 10.1016/j.cmet.2017.03.002.

14.

Retraction Notice to: Activation of the PPAR/PGC-1α Pathway Prevents a Bioenergetic Deficit and Effectively Improves a Mitochondrial Myopathy Phenotype.

Wenz T, Diaz F, Spiegelman BM, Moraes CT.

Cell Metab. 2016 Dec 13;24(6):889. doi: 10.1016/j.cmet.2016.11.006. No abstract available.

15.

The Cancer Drug Dasatinib Increases PGC-1α in Adipose Tissue but Has Adverse Effects on Glucose Tolerance in Obese Mice.

Sylow L, Long JZ, Lokurkar IA, Zeng X, Richter EA, Spiegelman BM.

Endocrinology. 2016 Nov;157(11):4184-4191. Epub 2016 Sep 2.

16.

Lysine-specific demethylase 1 promotes brown adipose tissue thermogenesis via repressing glucocorticoid activation.

Zeng X, Jedrychowski MP, Chen Y, Serag S, Lavery GG, Gygi SP, Spiegelman BM.

Genes Dev. 2016 Aug 15;30(16):1822-36. doi: 10.1101/gad.285312.116. Epub 2016 Aug 26.

17.

Cell biology of fat storage.

Cohen P, Spiegelman BM.

Mol Biol Cell. 2016 Aug 15;27(16):2523-7. doi: 10.1091/mbc.E15-10-0749. Review.

18.

CITED4 induces physiologic hypertrophy and promotes functional recovery after ischemic injury.

Bezzerides VJ, Platt C, Lerchenmüller C, Paruchuri K, Oh NL, Xiao C, Cao Y, Mann N, Spiegelman BM, Rosenzweig A.

JCI Insight. 2016 Jun 16;1(9). pii: e85904.

19.

The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria.

Long JZ, Svensson KJ, Bateman LA, Lin H, Kamenecka T, Lokurkar IA, Lou J, Rao RR, Chang MR, Jedrychowski MP, Paulo JA, Gygi SP, Griffin PR, Nomura DK, Spiegelman BM.

Cell. 2016 Jul 14;166(2):424-435. doi: 10.1016/j.cell.2016.05.071. Epub 2016 Jun 30.

20.

Corrigendum: Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1.

Chouchani ET, Kazak L, Jedrychowski MP, Lu GZ, Erickson BK, Szpyt J, Pierce KA, Laznik-Bogoslavski D, Vetrivelan R, Clish CB, Robinson AJ, Gygi SP, Spiegelman BM.

Nature. 2016 Aug 18;536(7616):360. doi: 10.1038/nature18279. Epub 2016 May 18. No abstract available.

PMID:
27281219

Supplemental Content

Loading ...
Support Center