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Items: 1 to 20 of 149


Retraction Notice to: Activation of the PPAR/PGC-1α Pathway Prevents a Bioenergetic Deficit and Effectively Improves a Mitochondrial Myopathy Phenotype.

Wenz T, Diaz F, Spiegelman BM, Moraes CT.

Cell Metab. 2016 Dec 13;24(6):889. doi: 10.1016/j.cmet.2016.11.006. No abstract available.


The Cancer Drug Dasatinib Increases PGC-1α in Adipose Tissue but Has Adverse Effects on Glucose Tolerance in Obese Mice.

Sylow L, Long JZ, Lokurkar IA, Zeng X, Richter EA, Spiegelman BM.

Endocrinology. 2016 Nov;157(11):4184-4191.


Lysine-specific demethylase 1 promotes brown adipose tissue thermogenesis via repressing glucocorticoid activation.

Zeng X, Jedrychowski MP, Chen Y, Serag S, Lavery GG, Gygi SP, Spiegelman BM.

Genes Dev. 2016 Aug 15;30(16):1822-36. doi: 10.1101/gad.285312.116.


Cell biology of fat storage.

Cohen P, Spiegelman BM.

Mol Biol Cell. 2016 Aug 15;27(16):2523-7. doi: 10.1091/mbc.E15-10-0749.


CITED4 induces physiologic hypertrophy and promotes functional recovery after ischemic injury.

Bezzerides VJ, Platt C, Lerchenmüller C, Paruchuri K, Oh NL, Xiao C, Cao Y, Mann N, Spiegelman BM, Rosenzweig A.

JCI Insight. 2016 Jun 16;1(9). pii: e85904.


The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria.

Long JZ, Svensson KJ, Bateman LA, Lin H, Kamenecka T, Lokurkar IA, Lou J, Rao RR, Chang MR, Jedrychowski MP, Paulo JA, Gygi SP, Griffin PR, Nomura DK, Spiegelman BM.

Cell. 2016 Jul 14;166(2):424-35. doi: 10.1016/j.cell.2016.05.071.


Corrigendum: Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1.

Chouchani ET, Kazak L, Jedrychowski MP, Lu GZ, Erickson BK, Szpyt J, Pierce KA, Laznik-Bogoslavski D, Vetrivelan R, Clish CB, Robinson AJ, Gygi SP, Spiegelman BM.

Nature. 2016 Aug 18;536(7616):360. doi: 10.1038/nature18279. No abstract available.


Attenuated PGC-1α Isoforms following Endurance Exercise with Blood Flow Restriction.

Conceição MS, Chacon-Mikahil MP, Telles GD, Libardi CA, Júnior EM, Vechin FC, DE Andrade AL, Gáspari AF, Brum PC, Cavaglieri CR, Serag S, Spiegelman BM, Hawley JA, Camera DM.

Med Sci Sports Exerc. 2016 Sep;48(9):1699-707. doi: 10.1249/MSS.0000000000000970.


Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1.

Chouchani ET, Kazak L, Jedrychowski MP, Lu GZ, Erickson BK, Szpyt J, Pierce KA, Laznik-Bogoslavski D, Vetrivelan R, Clish CB, Robinson AJ, Gygi SP, Spiegelman BM.

Nature. 2016 Apr 7;532(7597):112-6. doi: 10.1038/nature17399. Erratum in: Nature. 2016 Aug 18;536(7616):360.


A Secreted Slit2 Fragment Regulates Adipose Tissue Thermogenesis and Metabolic Function.

Svensson KJ, Long JZ, Jedrychowski MP, Cohen P, Lo JC, Serag S, Kir S, Shinoda K, Tartaglia JA, Rao RR, Chédotal A, Kajimura S, Gygi SP, Spiegelman BM.

Cell Metab. 2016 Mar 8;23(3):454-66. doi: 10.1016/j.cmet.2016.01.008.


PTH/PTHrP Receptor Mediates Cachexia in Models of Kidney Failure and Cancer.

Kir S, Komaba H, Garcia AP, Economopoulos KP, Liu W, Lanske B, Hodin RA, Spiegelman BM.

Cell Metab. 2016 Feb 9;23(2):315-23. doi: 10.1016/j.cmet.2015.11.003.


A creatine-driven substrate cycle enhances energy expenditure and thermogenesis in beige fat.

Kazak L, Chouchani ET, Jedrychowski MP, Erickson BK, Shinoda K, Cohen P, Vetrivelan R, Lu GZ, Laznik-Bogoslavski D, Hasenfuss SC, Kajimura S, Gygi SP, Spiegelman BM.

Cell. 2015 Oct 22;163(3):643-55. doi: 10.1016/j.cell.2015.09.035.


Brown and Beige Fat: Physiological Roles beyond Heat Generation.

Kajimura S, Spiegelman BM, Seale P.

Cell Metab. 2015 Oct 6;22(4):546-59. doi: 10.1016/j.cmet.2015.09.007. Review.


Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry.

Jedrychowski MP, Wrann CD, Paulo JA, Gerber KK, Szpyt J, Robinson MM, Nair KS, Gygi SP, Spiegelman BM.

Cell Metab. 2015 Oct 6;22(4):734-40. doi: 10.1016/j.cmet.2015.08.001.


Brown and Beige Fat: Molecular Parts of a Thermogenic Machine.

Cohen P, Spiegelman BM.

Diabetes. 2015 Jul;64(7):2346-51. doi: 10.2337/db15-0318. Review.


The future of brown adipose tissues in the treatment of type 2 diabetes.

Schrauwen P, van Marken Lichtenbelt WD, Spiegelman BM.

Diabetologia. 2015 Aug;58(8):1704-7. doi: 10.1007/s00125-015-3611-y.


miR-222 is necessary for exercise-induced cardiac growth and protects against pathological cardiac remodeling.

Liu X, Xiao J, Zhu H, Wei X, Platt C, Damilano F, Xiao C, Bezzerides V, Boström P, Che L, Zhang C, Spiegelman BM, Rosenzweig A.

Cell Metab. 2015 Apr 7;21(4):584-95. doi: 10.1016/j.cmet.2015.02.014.


Combined training enhances skeletal muscle mitochondrial oxidative capacity independent of age.

Irving BA, Lanza IR, Henderson GC, Rao RR, Spiegelman BM, Nair KS.

J Clin Endocrinol Metab. 2015 Apr;100(4):1654-63. doi: 10.1210/jc.2014-3081.


Appearance and disappearance of the mRNA signature characteristic of Treg cells in visceral adipose tissue: age, diet, and PPARγ effects.

Cipolletta D, Cohen P, Spiegelman BM, Benoist C, Mathis D.

Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):482-7. doi: 10.1073/pnas.1423486112.


An ERK/Cdk5 axis controls the diabetogenic actions of PPARγ.

Banks AS, McAllister FE, Camporez JP, Zushin PJ, Jurczak MJ, Laznik-Bogoslavski D, Shulman GI, Gygi SP, Spiegelman BM.

Nature. 2015 Jan 15;517(7534):391-5. doi: 10.1038/nature13887.

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