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Items: 1 to 20 of 27


Short Communication: Accumulation of Neutral Lipids in Liver and Aorta of Nef-Transgenic Mice.

Pushkarsky T, Shilov E, Kruglova N, Naumann R, Brichacek B, Jennelle L, Sviridov D, Kruglov A, Nedospasov SA, Bukrinsky M.

AIDS Res Hum Retroviruses. 2017 Jan;33(1):57-60. doi: 10.1089/AID.2016.0128. Epub 2016 Oct 25.


Interaction Between HIV-1 Nef and Calnexin: From Modeling to Small Molecule Inhibitors Reversing HIV-Induced Lipid Accumulation.

Hunegnaw R, Vassylyeva M, Dubrovsky L, Pushkarsky T, Sviridov D, Anashkina AA, Üren A, Brichacek B, Vassylyev DG, Adzhubei AA, Bukrinsky M.

Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1758-71. doi: 10.1161/ATVBAHA.116.307997. Epub 2016 Jul 28.


Cellular minichromosome maintenance complex component 5 (MCM5) is incorporated into HIV-1 virions and modulates viral replication in the newly infected cells.

Santos S, Obukhov Y, Nekhai S, Pushkarsky T, Brichacek B, Bukrinsky M, Iordanskiy S.

Virology. 2016 Oct;497:11-22. doi: 10.1016/j.virol.2016.06.023. Epub 2016 Jul 12.


Live Cell Imaging of ABCA1 Downregulation by HIV-1 Nef in an Experimental Model of HeLa ABCA1-GFP.

Siegel J, Darwish C, Popratiloff A, Bukrinsky M, Brichacek B.

AIDS Res Hum Retroviruses. 2016 Sep;32(9):872-3. doi: 10.1089/aid.2015.0362. Epub 2016 May 2. No abstract available.


Analysis of ABCA1 and Cholesterol Efflux in HIV-Infected Cells.

Mukhamedova N, Brichacek B, Darwish C, Popratiloff A, Sviridov D, Bukrinsky M.

Methods Mol Biol. 2016;1354:281-92. doi: 10.1007/978-1-4939-3046-3_19.


HIV-1 infection of macrophages induces retention of cholesterol transporter ABCA1 in the endoplasmic reticulum.

Brichacek B, Darwish C, Popratiloff A, Dubrovsky L, Bukrinsky M.

AIDS Res Hum Retroviruses. 2014 Oct;30(10):947-8. doi: 10.1089/aid.2014.0156. Epub 2014 Sep 8. No abstract available.


HIV-1 protein Nef inhibits activity of ATP-binding cassette transporter A1 by targeting endoplasmic reticulum chaperone calnexin.

Jennelle L, Hunegnaw R, Dubrovsky L, Pushkarsky T, Fitzgerald ML, Sviridov D, Popratiloff A, Brichacek B, Bukrinsky M.

J Biol Chem. 2014 Oct 17;289(42):28870-84. doi: 10.1074/jbc.M114.583591. Epub 2014 Aug 28.


In vivo evaluation of safety and toxicity of a Lactobacillus jensenii producing modified cyanovirin-N in a rhesus macaque vaginal challenge model.

Brichacek B, Lagenaur LA, Lee PP, Venzon D, Hamer DH.

PLoS One. 2013 Nov 12;8(11):e78817. doi: 10.1371/journal.pone.0078817. eCollection 2013.


The level of CD147 expression correlates with cyclophilin-induced signalling and chemotaxis.

Trachtenberg A, Pushkarsky T, Heine S, Constant S, Brichacek B, Bukrinsky M.

BMC Res Notes. 2011 Oct 11;4:396. doi: 10.1186/1756-0500-4-396.


Prevention of vaginal SHIV transmission in macaques by a live recombinant Lactobacillus.

Lagenaur LA, Sanders-Beer BE, Brichacek B, Pal R, Liu X, Liu Y, Yu R, Venzon D, Lee PP, Hamer DH.

Mucosal Immunol. 2011 Nov;4(6):648-57. doi: 10.1038/mi.2011.30. Epub 2011 Jul 6.


Contrasting roles for TLR ligands in HIV-1 pathogenesis.

Brichacek B, Vanpouille C, Kiselyeva Y, Biancotto A, Merbah M, Hirsch I, Lisco A, Grivel JC, Margolis L.

PLoS One. 2010 Sep 20;5(9). pii: e12831. doi: 10.1371/journal.pone.0012831.


Significantly reduced CCR5-tropic HIV-1 replication in vitro in cells from subjects previously immunized with Vaccinia Virus.

Weinstein RS, Weinstein MM, Alibek K, Bukrinsky MI, Brichacek B.

BMC Immunol. 2010 May 18;11:23. doi: 10.1186/1471-2172-11-23.


HIV-1 sexual transmission: early events of HIV-1 infection of human cervico-vaginal tissue in an optimized ex vivo model.

Saba E, Grivel JC, Vanpouille C, Brichacek B, Fitzgerald W, Margolis L, Lisco A.

Mucosal Immunol. 2010 May;3(3):280-90. doi: 10.1038/mi.2010.2. Epub 2010 Feb 10.


A new class of dual-targeted antivirals: monophosphorylated acyclovir prodrug derivatives suppress both human immunodeficiency virus type 1 and herpes simplex virus type 2.

Vanpouille C, Lisco A, Derudas M, Saba E, Grivel JC, Brichacek B, Scrimieri F, Schinazi R, Schols D, McGuigan C, Balzarini J, Margolis L.

J Infect Dis. 2010 Feb 15;201(4):635-43. doi: 10.1086/650343.


Movements of HIV-virions in human cervical mucus.

Boukari H, Brichacek B, Stratton P, Mahoney SF, Lifson JD, Margolis L, Nossal R.

Biomacromolecules. 2009 Sep 14;10(9):2482-8. doi: 10.1021/bm900344q.


Toxoplasma gondii inhibits R5 HIV-1 replication in human lymphoid tissues ex vivo.

Sassi A, Brichacek B, Hieny S, Yarovinsky F, Golding H, Grivel JC, Sher A, Margolis L.

Microbes Infect. 2009 Dec;11(14-15):1106-13. doi: 10.1016/j.micinf.2009.08.004. Epub 2009 Aug 9.


Mechanisms associated with HIV-1 resistance to acyclovir by the V75I mutation in reverse transcriptase.

Tchesnokov EP, Obikhod A, Massud I, Lisco A, Vanpouille C, Brichacek B, Balzarini J, McGuigan C, Derudas M, Margolis L, Schinazi RF, Götte M.

J Biol Chem. 2009 Aug 7;284(32):21496-504. doi: 10.1074/jbc.M109.024026. Epub 2009 Jun 9.


A highly sensitive and dynamic immunofluorescent cytometric bead assay for the detection of HIV-1 p24.

Biancotto A, Brichacek B, Chen SS, Fitzgerald W, Lisco A, Vanpouille C, Margolis L, Grivel JC.

J Virol Methods. 2009 Apr;157(1):98-101. doi: 10.1016/j.jviromet.2008.11.013. Epub 2009 Jan 6.


Acyclovir is activated into a HIV-1 reverse transcriptase inhibitor in herpesvirus-infected human tissues.

Lisco A, Vanpouille C, Tchesnokov EP, Grivel JC, Biancotto A, Brichacek B, Elliott J, Fromentin E, Shattock R, Anton P, Gorelick R, Balzarini J, McGuigan C, Derudas M, Götte M, Schinazi RF, Margolis L.

Cell Host Microbe. 2008 Sep 11;4(3):260-270. doi: 10.1016/j.chom.2008.07.008.


Interactions between human immunodeficiency virus type 1 and vaccinia virus in human lymphoid tissue ex vivo.

Vanpouille C, Biancotto A, Lisco A, Brichacek B.

J Virol. 2007 Nov;81(22):12458-64. Epub 2007 Sep 5.

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