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Items: 1 to 20 of 289

1.

HBEGF+ macrophages in rheumatoid arthritis induce fibroblast invasiveness.

Kuo D, Ding J, Cohn IS, Zhang F, Wei K, Rao DA, Rozo C, Sokhi UK, Shanaj S, Oliver DJ, Echeverria AP, DiCarlo EF, Brenner MB, Bykerk VP, Goodman SM, Raychaudhuri S, Rätsch G, Ivashkiv LB, Donlin LT.

Sci Transl Med. 2019 May 8;11(491). pii: eaau8587. doi: 10.1126/scitranslmed.aau8587.

PMID:
31068444
2.

Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry.

Zhang F, Wei K, Slowikowski K, Fonseka CY, Rao DA, Kelly S, Goodman SM, Tabechian D, Hughes LB, Salomon-Escoto K, Watts GFM, Jonsson AH, Rangel-Moreno J, Meednu N, Rozo C, Apruzzese W, Eisenhaure TM, Lieb DJ, Boyle DL, Mandelin AM 2nd; Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Consortium, Boyce BF, DiCarlo E, Gravallese EM, Gregersen PK, Moreland L, Firestein GS, Hacohen N, Nusbaum C, Lederer JA, Perlman H, Pitzalis C, Filer A, Holers VM, Bykerk VP, Donlin LT, Anolik JH, Brenner MB, Raychaudhuri S.

Nat Immunol. 2019 May 6. doi: 10.1038/s41590-019-0378-1. [Epub ahead of print]

PMID:
31061532
3.

Interactions between cadherin-11 and platelet-derived growth factor receptor-alpha signaling link cell adhesion and proliferation.

Madarampalli B, Watts GFM, Panipinto PM, Nguygen HN, Brenner MB, Noss EH.

Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1516-1524. doi: 10.1016/j.bbadis.2019.03.001. Epub 2019 Mar 13.

PMID:
30876808
4.

Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions.

Gutierrez-Arcelus M, Teslovich N, Mola AR, Polidoro RB, Nathan A, Kim H, Hannes S, Slowikowski K, Watts GFM, Korsunsky I, Brenner MB, Raychaudhuri S, Brennan PJ.

Nat Commun. 2019 Feb 8;10(1):687. doi: 10.1038/s41467-019-08604-4.

5.

Author Correction: γδ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis.

Kohlgruber AC, Gal-Oz ST, LaMarche NM, Shimazaki M, Duquette D, Koay HF, Nguyen HN, Mina AI, Paras T, Tavakkoli A, von Andrian U, Uldrich AP, Godfrey DI, Banks AS, Shay T, Brenner MB, Lynch L.

Nat Immunol. 2019 Mar;20(3):373. doi: 10.1038/s41590-019-0330-4.

PMID:
30728493
6.

Plateletpheresis-associated lymphopenia in frequent platelet donors.

Gansner JM, Rahmani M, Jonsson AH, Fortin BM, Brimah I, Ellis M, Smeland-Wagman R, Li ZJ, Schenkel JM, Brenner MB, Yefidoff-Freedman R, Sloan SR, Berliner N, Issa NC, Baden LR, Longo DL, Wesemann DR, Neuberg D, Rao DA, Kaufman RM.

Blood. 2019 Feb 7;133(6):605-614. doi: 10.1182/blood-2018-09-873125. Epub 2018 Nov 14.

PMID:
30429159
7.

Metabolic reprogramming of natural killer cells in obesity limits antitumor responses.

Michelet X, Dyck L, Hogan A, Loftus RM, Duquette D, Wei K, Beyaz S, Tavakkoli A, Foley C, Donnelly R, O'Farrelly C, Raverdeau M, Vernon A, Pettee W, O'Shea D, Nikolajczyk BS, Mills KHG, Brenner MB, Finlay D, Lynch L.

Nat Immunol. 2018 Dec;19(12):1330-1340. doi: 10.1038/s41590-018-0251-7. Epub 2018 Nov 12.

PMID:
30420624
8.

Mixed-effects association of single cells identifies an expanded effector CD4+ T cell subset in rheumatoid arthritis.

Fonseka CY, Rao DA, Teslovich NC, Korsunsky I, Hannes SK, Slowikowski K, Gurish MF, Donlin LT, Lederer JA, Weinblatt ME, Massarotti EM, Coblyn JS, Helfgott SM, Todd DJ, Bykerk VP, Karlson EW, Ermann J, Lee YC, Brenner MB, Raychaudhuri S.

Sci Transl Med. 2018 Oct 17;10(463). pii: eaaq0305. doi: 10.1126/scitranslmed.aaq0305.

9.

Innate T Cells Govern Adipose Tissue Biology.

LaMarche NM, Kohlgruber AC, Brenner MB.

J Immunol. 2018 Oct 1;201(7):1827-1834. doi: 10.4049/jimmunol.1800556. Review.

PMID:
30224362
10.

High-throughput identification of noncoding functional SNPs via type IIS enzyme restriction.

Li G, Martínez-Bonet M, Wu D, Yang Y, Cui J, Nguyen HN, Cunin P, Levescot A, Bai M, Westra HJ, Okada Y, Brenner MB, Raychaudhuri S, Hendrickson EA, Maas RL, Nigrovic PA.

Nat Genet. 2018 Aug;50(8):1180-1188. doi: 10.1038/s41588-018-0159-z. Epub 2018 Jul 16.

11.

Methods for high-dimensonal analysis of cells dissociated from cyropreserved synovial tissue.

Donlin LT, Rao DA, Wei K, Slowikowski K, McGeachy MJ, Turner JD, Meednu N, Mizoguchi F, Gutierrez-Arcelus M, Lieb DJ, Keegan J, Muskat K, Hillman J, Rozo C, Ricker E, Eisenhaure TM, Li S, Browne EP, Chicoine A, Sutherby D, Noma A; Accelerating Medicines Partnership RA/SLE Network, Nusbaum C, Kelly S, Pernis AB, Ivashkiv LB, Goodman SM, Robinson WH, Utz PJ, Lederer JA, Gravallese EM, Boyce BF, Hacohen N, Pitzalis C, Gregersen PK, Firestein GS, Raychaudhuri S, Moreland LW, Holers VM, Bykerk VP, Filer A, Boyle DL, Brenner MB, Anolik JH.

Arthritis Res Ther. 2018 Jul 11;20(1):139. doi: 10.1186/s13075-018-1631-y.

12.

γδ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis.

Kohlgruber AC, Gal-Oz ST, LaMarche NM, Shimazaki M, Duquette D, Koay HF, Nguyen HN, Mina AI, Paras T, Tavakkoli A, von Andrian U, Uldrich AP, Godfrey DI, Banks AS, Shay T, Brenner MB, Lynch L.

Nat Immunol. 2018 May;19(5):464-474. doi: 10.1038/s41590-018-0094-2. Epub 2018 Apr 18. Erratum in: Nat Immunol. 2019 Mar;20(3):373.

PMID:
29670241
13.

Lysosome-Mediated Plasma Membrane Repair Is Dependent on the Small GTPase Arl8b and Determines Cell Death Type in Mycobacterium tuberculosis Infection.

Michelet X, Tuli A, Gan H, Geadas C, Sharma M, Remold HG, Brenner MB.

J Immunol. 2018 May 1;200(9):3160-3169. doi: 10.4049/jimmunol.1700829. Epub 2018 Mar 28.

14.

Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis.

Mizoguchi F, Slowikowski K, Wei K, Marshall JL, Rao DA, Chang SK, Nguyen HN, Noss EH, Turner JD, Earp BE, Blazar PE, Wright J, Simmons BP, Donlin LT, Kalliolias GD, Goodman SM, Bykerk VP, Ivashkiv LB, Lederer JA, Hacohen N, Nigrovic PA, Filer A, Buckley CD, Raychaudhuri S, Brenner MB.

Nat Commun. 2018 Feb 23;9(1):789. doi: 10.1038/s41467-018-02892-y.

15.

Functional genomics of stromal cells in chronic inflammatory diseases.

Slowikowski K, Wei K, Brenner MB, Raychaudhuri S.

Curr Opin Rheumatol. 2018 Jan;30(1):65-71. doi: 10.1097/BOR.0000000000000455. Review.

16.

Stromal cell cadherin-11 regulates adipose tissue inflammation and diabetes.

Chang SK, Kohlgruber AC, Mizoguchi F, Michelet X, Wolf BJ, Wei K, Lee PY, Lynch L, Duquette D, Ceperuelo-Mallafré V, Banks AS, Brenner MB.

J Clin Invest. 2017 Sep 1;127(9):3300-3312. doi: 10.1172/JCI86881. Epub 2017 Jul 31.

17.

Structural determination of lipid antigens captured at the CD1d-T-cell receptor interface.

Brennan PJ, Cheng TY, Pellicci DG, Watts GFM, Veerapen N, Young DC, Rossjohn J, Besra GS, Godfrey DI, Brenner MB, Moody DB.

Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):8348-8353. doi: 10.1073/pnas.1705882114. Epub 2017 Jul 17.

18.

Adipose Type One Innate Lymphoid Cells Regulate Macrophage Homeostasis through Targeted Cytotoxicity.

Boulenouar S, Michelet X, Duquette D, Alvarez D, Hogan AE, Dold C, O'Connor D, Stutte S, Tavakkoli A, Winters D, Exley MA, O'Shea D, Brenner MB, von Andrian U, Lynch L.

Immunity. 2017 Feb 21;46(2):273-286. doi: 10.1016/j.immuni.2017.01.008.

19.

Autocrine Loop Involving IL-6 Family Member LIF, LIF Receptor, and STAT4 Drives Sustained Fibroblast Production of Inflammatory Mediators.

Nguyen HN, Noss EH, Mizoguchi F, Huppertz C, Wei KS, Watts GFM, Brenner MB.

Immunity. 2017 Feb 21;46(2):220-232. doi: 10.1016/j.immuni.2017.01.004.

20.

Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis.

Rao DA, Gurish MF, Marshall JL, Slowikowski K, Fonseka CY, Liu Y, Donlin LT, Henderson LA, Wei K, Mizoguchi F, Teslovich NC, Weinblatt ME, Massarotti EM, Coblyn JS, Helfgott SM, Lee YC, Todd DJ, Bykerk VP, Goodman SM, Pernis AB, Ivashkiv LB, Karlson EW, Nigrovic PA, Filer A, Buckley CD, Lederer JA, Raychaudhuri S, Brenner MB.

Nature. 2017 Feb 1;542(7639):110-114. doi: 10.1038/nature20810.

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