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Items: 1 to 20 of 109

1.

PHD3 Acts as Tumor Suppressor in Mouse Osteosarcoma and Influences Tumor Vascularization via PDGF-C Signaling.

Egners A, Rezaei M, Kuzmanov A, Poitz DM, Streichert D, Müller-Reichert T, Wielockx B, Breier G.

Cancers (Basel). 2018 Dec 6;10(12). pii: E496. doi: 10.3390/cancers10120496.

2.

Heparanase and Thrombin: Common Signalling Pathways in Melanoma Cells?

Breier G.

Thromb Haemost. 2018 Oct;118(10):1688-1689. doi: 10.1055/s-0038-1673329. Epub 2018 Oct 1. No abstract available.

PMID:
30273953
3.

Hematopoietic hypoxia-inducible factor 2α deficiency ameliorates pathological retinal neovascularization via modulation of endothelial cell apoptosis.

Korovina I, Neuwirth A, Sprott D, Weber S, Sardar Pasha SPB, Gercken B, Breier G, El-Armouche A, Deussen A, Karl MO, Wielockx B, Chavakis T, Klotzsche-von Ameln A.

FASEB J. 2019 Feb;33(2):1758-1770. doi: 10.1096/fj.201800430R. Epub 2018 Aug 29.

PMID:
30156910
4.

The expression of VE-cadherin in breast cancer cells modulates cell dynamics as a function of tumor differentiation and promotes tumor-endothelial cell interactions.

Rezaei M, Cao J, Friedrich K, Kemper B, Brendel O, Grosser M, Adrian M, Baretton G, Breier G, Schnittler HJ.

Histochem Cell Biol. 2018 Jan;149(1):15-30. doi: 10.1007/s00418-017-1619-8. Epub 2017 Nov 15.

PMID:
29143117
5.

Angiogenesis in metabolic-vascular disease.

Breier G, Chavakis T, Hirsch E.

Thromb Haemost. 2017 Jun 27;117(7):1289-1295. doi: 10.1160/TH17-05-0325. Epub 2017 Jun 8. Review.

PMID:
28594427
6.

Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis.

Van Welden S, De Vos M, Wielockx B, Tavernier SJ, Dullaers M, Neyt S, Descamps B, Devisscher L, Devriese S, Van den Bossche L, Holvoet T, Baeyens A, Correale C, D'Alessio S, Vanhove C, De Vos F, Verhasselt B, Breier G, Lambrecht BN, Janssens S, Carmeliet P, Danese S, Elewaut D, Laukens D, Hindryckx P.

J Pathol. 2017 Mar;241(4):547-558. doi: 10.1002/path.4861. Epub 2017 Jan 27.

PMID:
27981571
7.

Adipocyte-Specific Hypoxia-Inducible Factor 2α Deficiency Exacerbates Obesity-Induced Brown Adipose Tissue Dysfunction and Metabolic Dysregulation.

García-Martín R, Alexaki VI, Qin N, Rubín de Celis MF, Economopoulou M, Ziogas A, Gercken B, Kotlabova K, Phieler J, Ehrhart-Bornstein M, Bornstein SR, Eisenhofer G, Breier G, Blüher M, Hampe J, El-Armouche A, Chatzigeorgiou A, Chung KJ, Chavakis T.

Mol Cell Biol. 2015 Nov 16;36(3):376-93. doi: 10.1128/MCB.00430-15. Print 2016 Feb 1.

8.

VEGFR2 Signaling Prevents Colorectal Cancer Cell Senescence to Promote Tumorigenesis in Mice With Colitis.

Foersch S, Sperka T, Lindner C, Taut A, Rudolph KL, Breier G, Boxberger F, Rau TT, Hartmann A, Stürzl M, Wittkopf N, Haep L, Wirtz S, Neurath MF, Waldner MJ.

Gastroenterology. 2015 Jul;149(1):177-189.e10. doi: 10.1053/j.gastro.2015.03.016. Epub 2015 Mar 19.

PMID:
25797700
9.

Receptor tyrosine kinase inhibitors: Are they real tumor killers?

Gaumann AK, Kiefer F, Alfer J, Lang SA, Geissler EK, Breier G.

Int J Cancer. 2016 Feb 1;138(3):540-54. doi: 10.1002/ijc.29499. Epub 2015 Mar 11. Review.

10.

The inhibition of tyrosine kinase receptor signalling in leiomyosarcoma cells using the small molecule kinase inhibitor PTK787/ZK222584 (Vatalanib®).

Gaumann AK, Drexler HC, Lang SA, Stoeltzing O, Diermeier-Daucher S, Buchdunger E, Wood J, Bold G, Breier G.

Int J Oncol. 2014 Dec;45(6):2267-77. doi: 10.3892/ijo.2014.2683. Epub 2014 Sep 29.

11.

Endothelial cadherins in cancer.

Breier G, Grosser M, Rezaei M.

Cell Tissue Res. 2014 Mar;355(3):523-7. doi: 10.1007/s00441-014-1851-7. Epub 2014 Mar 12. Review.

PMID:
24619142
12.

PHD4 stimulates tumor angiogenesis in osteosarcoma cells via TGF-α.

Klotzsche-von Ameln A, Prade I, Grosser M, Kettelhake A, Rezaei M, Chavakis T, Flamme I, Wielockx B, Breier G.

Mol Cancer Res. 2013 Nov;11(11):1337-48. doi: 10.1158/1541-7786.MCR-13-0201. Epub 2013 Sep 18.

13.

Lack of vascular endothelial growth factor receptor-2/Flk1 signaling does not affect substantia nigra development.

Hermann A, Loewenbrück KF, Boldt Ä, Fiedler C, Maisel M, Kalucka J, Schwarz J, Breier G, Storch A.

Neurosci Lett. 2013 Oct 11;553:142-7. doi: 10.1016/j.neulet.2013.08.031. Epub 2013 Aug 29.

PMID:
23994060
14.

Loss of epithelial hypoxia-inducible factor prolyl hydroxylase 2 accelerates skin wound healing in mice.

Kalucka J, Ettinger A, Franke K, Mamlouk S, Singh RP, Farhat K, Muschter A, Olbrich S, Breier G, Katschinski DM, Huttner W, Weidemann A, Wielockx B.

Mol Cell Biol. 2013 Sep;33(17):3426-38. doi: 10.1128/MCB.00609-13. Epub 2013 Jun 24.

15.

A role for prolyl hydroxylase domain proteins in hippocampal synaptic plasticity.

Corcoran A, Kunze R, Harney SC, Breier G, Marti HH, O'Connor JJ.

Hippocampus. 2013 Oct;23(10):861-72. doi: 10.1002/hipo.22142. Epub 2013 Jun 6.

PMID:
23674383
16.

HIF prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady-state and stress.

Singh RP, Franke K, Kalucka J, Mamlouk S, Muschter A, Gembarska A, Grinenko T, Willam C, Naumann R, Anastassiadis K, Stewart AF, Bornstein S, Chavakis T, Breier G, Waskow C, Wielockx B.

Blood. 2013 Jun 27;121(26):5158-66. doi: 10.1182/blood-2012-12-471185. Epub 2013 May 10.

17.

Stress-stimulated volitional coping competencies and depression in multiple sclerosis.

Nielsen-Prohl J, Saliger J, Güldenberg V, Breier G, Karbe H.

J Psychosom Res. 2013 Mar;74(3):221-6. doi: 10.1016/j.jpsychores.2012.11.003. Epub 2012 Nov 22.

PMID:
23438712
18.

Spatial regulation of VEGF receptor endocytosis in angiogenesis.

Nakayama M, Nakayama A, van Lessen M, Yamamoto H, Hoffmann S, Drexler HC, Itoh N, Hirose T, Breier G, Vestweber D, Cooper JA, Ohno S, Kaibuchi K, Adams RH.

Nat Cell Biol. 2013 Mar;15(3):249-60. doi: 10.1038/ncb2679. Epub 2013 Jan 27.

19.

HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis.

Franke K, Kalucka J, Mamlouk S, Singh RP, Muschter A, Weidemann A, Iyengar V, Jahn S, Wieczorek K, Geiger K, Muders M, Sykes AM, Poitz DM, Ripich T, Otto T, Bergmann S, Breier G, Baretton G, Fong GH, Greaves DR, Bornstein S, Chavakis T, Fandrey J, Gassmann M, Wielockx B.

Blood. 2013 Feb 21;121(8):1436-45. doi: 10.1182/blood-2012-08-449181. Epub 2012 Dec 20.

20.

Interplay between neural-cadherin and vascular endothelial-cadherin in breast cancer progression.

Rezaei M, Friedrich K, Wielockx B, Kuzmanov A, Kettelhake A, Labelle M, Schnittler H, Baretton G, Breier G.

Breast Cancer Res. 2012 Dec 6;14(6):R154. doi: 10.1186/bcr3367.

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