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Items: 1 to 20 of 73


Matrix Gla protein deficiency impairs nasal septum growth, causing midface hypoplasia.

Marulanda J, Eimar H, McKee MD, Berkvens M, Nelea V, Roman H, Borrás T, Tamimi F, Ferron M, Murshed M.

J Biol Chem. 2017 Jul 7;292(27):11400-11412. doi: 10.1074/jbc.M116.769802. Epub 2017 May 9.


The Pathway From Genes to Gene Therapy in Glaucoma: A Review of Possibilities for Using Genes as Glaucoma Drugs.

Borrás T.

Asia Pac J Ophthalmol (Phila). 2017 Jan-Feb;6(1):80-93. doi: 10.22608/APO.2016126. Review.


A single gene connects stiffness in glaucoma and the vascular system.

Borrás T.

Exp Eye Res. 2017 May;158:13-22. doi: 10.1016/j.exer.2016.08.022. Epub 2016 Sep 1. Review.


Microglia Transcriptome Changes in a Model of Depressive Behavior after Immune Challenge.

Gonzalez-Pena D, Nixon SE, O'Connor JC, Southey BR, Lawson MA, McCusker RH, Borras T, Machuca D, Hernandez AG, Dantzer R, Kelley KW, Rodriguez-Zas SL.

PLoS One. 2016 Mar 9;11(3):e0150858. doi: 10.1371/journal.pone.0150858. eCollection 2016.


Inducible scAAV2.GRE.MMP1 lowers IOP long-term in a large animal model for steroid-induced glaucoma gene therapy.

Borrás T, Buie LK, Spiga MG.

Gene Ther. 2016 May;23(5):438-49. doi: 10.1038/gt.2016.14. Epub 2016 Feb 8.


Exfoliation syndrome: assembling the puzzle pieces.

Pasquale LR, Borrás T, Fingert JH, Wiggs JL, Ritch R.

Acta Ophthalmol. 2016 Sep;94(6):e505-12. doi: 10.1111/aos.12918. Epub 2015 Dec 9.


A Novel Mgp-Cre Knock-In Mouse Reveals an Anticalcification/Antistiffness Candidate Gene in the Trabecular Meshwork and Peripapillary Scleral Region.

Borrás T, Smith MH, Buie LK.

Invest Ophthalmol Vis Sci. 2015 Apr;56(4):2203-14. doi: 10.1167/iovs.15-16460.


Prevention of nocturnal elevation of intraocular pressure by gene transfer of dominant-negative RhoA in rats.

Borrás T, Buie LK, Spiga MG, Carabana J.

JAMA Ophthalmol. 2015 Feb;133(2):182-90. doi: 10.1001/jamaophthalmol.2014.4747.


The cellular and molecular biology of the iris, an overlooked tissue: the iris and pseudoexfoliation glaucoma.

Borrás T.

J Glaucoma. 2014 Oct-Nov;23(8 Suppl 1):S39-42. doi: 10.1097/IJG.0000000000000104. Review.


The effects of myocilin expression on functionally relevant trabecular meshwork genes: a mini-review.

Borrás T.

J Ocul Pharmacol Ther. 2014 Mar-Apr;30(2-3):202-12. doi: 10.1089/jop.2013.0218. Epub 2014 Feb 24. Review.


Attenuation of chondrogenic transformation in vascular smooth muscle by dietary quercetin in the MGP-deficient mouse model.

Beazley KE, Lima F, Borras T, Nurminskaya M.

PLoS One. 2013 Sep 30;8(9):e76210. doi: 10.1371/journal.pone.0076210. eCollection 2013.


Tissue plasminogen activator in trabecular meshwork attenuates steroid induced outflow resistance in mice.

Kumar S, Shah S, Tang HM, Smith M, Borrás T, Danias J.

PLoS One. 2013 Aug 19;8(8):e72447. doi: 10.1371/journal.pone.0072447. eCollection 2013.


Development of a model of elevated intraocular pressure in rats by gene transfer of bone morphogenetic protein 2.

Buie LK, Karim MZ, Smith MH, Borrás T.

Invest Ophthalmol Vis Sci. 2013 Aug 13;54(8):5441-55. doi: 10.1167/iovs.13-11651.


Molecular biomarkers in glaucoma.

Bhattacharya SK, Lee RK, Grus FH; Seventh ARVO/Pfizer Ophthalmics Research Institute Conference Working Group.

Invest Ophthalmol Vis Sci. 2013 Jan 7;54(1):121-31. doi: 10.1167/iovs.12-11067. No abstract available.


Cystatin a, a potential common link for mutant myocilin causative glaucoma.

Kennedy KD, AnithaChristy SA, Buie LK, Borrás T.

PLoS One. 2012;7(5):e36301. doi: 10.1371/journal.pone.0036301. Epub 2012 May 15.


Advances in glaucoma treatment and management: gene therapy.

Borrás T.

Invest Ophthalmol Vis Sci. 2012 May 4;53(5):2506-10. doi: 10.1167/iovs.12-9483o. No abstract available.


Smoking cessation in hospital workers: effectiveness of a coordinated program in 33 hospitals in Catalonia (Spain).

Martínez C, Martínez-Sánchez JM, Ballbè M, Nieva G, Fu M, Puig M, Carabasa E, Sánchez-García JM, Saltó E, Fernández E; Tobacco Cessation Program Project Coordinators.

Cancer Nurs. 2012 Sep-Oct;35(5):327-36.


Gene therapy strategies in glaucoma and application for steroid-induced hypertension.

Borrás T.

Saudi J Ophthalmol. 2011 Oct;25(4):353-62. doi: 10.1016/j.sjopt.2011.07.005. Epub 2011 May 8.


Evidence for a role of angiopoietin-like 7 (ANGPTL7) in extracellular matrix formation of the human trabecular meshwork: implications for glaucoma.

Comes N, Buie LK, Borrás T.

Genes Cells. 2011 Feb;16(2):243-59. doi: 10.1111/j.1365-2443.2010.01483.x. Epub 2010 Dec 30.


Development of a gene therapy virus with a glucocorticoid-inducible MMP1 for the treatment of steroid glaucoma.

Spiga MG, Borrás T.

Invest Ophthalmol Vis Sci. 2010 Jun;51(6):3029-41. doi: 10.1167/iovs.09-4918. Epub 2010 Jan 20.

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