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Items: 1 to 20 of 119

1.
2.

Instructive Role of MLL-Fusion Proteins Revealed by a Model of t(4;11) Pro-B Acute Lymphoblastic Leukemia.

Lin S, Luo RT, Ptasinska A, Kerry J, Assi SA, Wunderlich M, Imamura T, Kaberlein JJ, Rayes A, Althoff MJ, Anastasi J, O'Brien MM, Meetei AR, Milne TA, Bonifer C, Mulloy JC, Thirman MJ.

Cancer Cell. 2016 Nov 14;30(5):737-749. doi: 10.1016/j.ccell.2016.10.008.

PMID:
27846391
3.

Cooperative binding of AP-1 and TEAD4 modulates the balance between vascular smooth muscle and hemogenic cell fate.

Obier N, Cauchy P, Assi SA, Gilmour J, Lie-A-Ling M, Lichtinger M, Hoogenkamp M, Noailles L, Cockerill PN, Lacaud G, Kouskoff V, Bonifer C.

Development. 2016 Dec 1;143(23):4324-4340.

4.
5.

Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers.

Illendula A, Gilmour J, Grembecka J, Tirumala VS, Boulton A, Kuntimaddi A, Schmidt C, Wang L, Pulikkan JA, Zong H, Parlak M, Kuscu C, Pickin A, Zhou Y, Gao Y, Mishra L, Adli M, Castilla LH, Rajewski RA, Janes KA, Guzman ML, Bonifer C, Bushweller JH.

EBioMedicine. 2016 Jun;8:117-31. doi: 10.1016/j.ebiom.2016.04.032.

6.

Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation.

Goode DK, Obier N, Vijayabaskar MS, Lie-A-Ling M, Lilly AJ, Hannah R, Lichtinger M, Batta K, Florkowska M, Patel R, Challinor M, Wallace K, Gilmour J, Assi SA, Cauchy P, Hoogenkamp M, Westhead DR, Lacaud G, Kouskoff V, Göttgens B, Bonifer C.

Dev Cell. 2016 Mar 7;36(5):572-87. doi: 10.1016/j.devcel.2016.01.024.

7.

Inducible chromatin priming is associated with the establishment of immunological memory in T cells.

Bevington SL, Cauchy P, Piper J, Bertrand E, Lalli N, Jarvis RC, Gilding LN, Ott S, Bonifer C, Cockerill PN.

EMBO J. 2016 Mar 1;35(5):515-35. doi: 10.15252/embj.201592534.

8.

NFATc1 releases BCL6-dependent repression of CCR2 agonist expression in peritoneal macrophages from Saccharomyces cerevisiae infected mice.

Busch R, Murti K, Liu J, Patra AK, Muhammad K, Knobeloch KP, Lichtinger M, Bonifer C, Wörtge S, Waisman A, Reifenberg K, Ellenrieder V, Serfling E, Avots A.

Eur J Immunol. 2016 Mar;46(3):634-46. doi: 10.1002/eji.201545925.

PMID:
26631626
9.

Wellington-bootstrap: differential DNase-seq footprinting identifies cell-type determining transcription factors.

Piper J, Assi SA, Cauchy P, Ladroue C, Cockerill PN, Bonifer C, Ott S.

BMC Genomics. 2015 Nov 25;16:1000. doi: 10.1186/s12864-015-2081-4.

10.

UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO.

Goyama S, Schibler J, Gasilina A, Shrestha M, Lin S, Link KA, Chen J, Whitman SP, Bloomfield CD, Nicolet D, Assi SA, Ptasinska A, Heidenreich O, Bonifer C, Kitamura T, Nassar NN, Mulloy JC.

Leukemia. 2016 Mar;30(3):728-39. doi: 10.1038/leu.2015.275.

11.

C/EBPα Activates Pre-existing and De Novo Macrophage Enhancers during Induced Pre-B Cell Transdifferentiation and Myelopoiesis.

van Oevelen C, Collombet S, Vicent G, Hoogenkamp M, Lepoivre C, Badeaux A, Bussmann L, Sardina JL, Thieffry D, Beato M, Shi Y, Bonifer C, Graf T.

Stem Cell Reports. 2015 Aug 11;5(2):232-47. doi: 10.1016/j.stemcr.2015.06.007.

12.

Chronic FLT3-ITD Signaling in Acute Myeloid Leukemia Is Connected to a Specific Chromatin Signature.

Cauchy P, James SR, Zacarias-Cabeza J, Ptasinska A, Imperato MR, Assi SA, Piper J, Canestraro M, Hoogenkamp M, Raghavan M, Loke J, Akiki S, Clokie SJ, Richards SJ, Westhead DR, Griffiths MJ, Ott S, Bonifer C, Cockerill PN.

Cell Rep. 2015 Aug 4;12(5):821-36. doi: 10.1016/j.celrep.2015.06.069.

13.

The leukemia-associated RUNX1/ETO oncoprotein confers a mutator phenotype.

Forster VJ, Nahari MH, Martinez-Soria N, Bradburn AK, Ptasinska A, Assi SA, Fordham SE, McNeil H, Bonifer C, Heidenreich O, Allan JM.

Leukemia. 2016 Jan;30(1):250-3. doi: 10.1038/leu.2015.133. No abstract available.

14.

Developmental-stage-dependent transcriptional response to leukaemic oncogene expression.

Regha K, Assi SA, Tsoulaki O, Gilmour J, Lacaud G, Bonifer C.

Nat Commun. 2015 May 28;6:7203. doi: 10.1038/ncomms8203.

15.

RUNX1/ETO blocks selectin-mediated adhesion via epigenetic silencing of PSGL-1.

Ponnusamy K, Kohrs N, Ptasinska A, Assi SA, Herold T, Hiddemann W, Lausen J, Bonifer C, Henschler R, Wichmann C.

Oncogenesis. 2015 Apr 13;4:e146. doi: 10.1038/oncsis.2015.6.

PMID:
25867177
16.

The RUNX1-PU.1 axis in the control of hematopoiesis.

Imperato MR, Cauchy P, Obier N, Bonifer C.

Int J Hematol. 2015 Apr;101(4):319-29. doi: 10.1007/s12185-015-1762-8. Review.

PMID:
25749719
17.

Cytokine and proinflammatory gene expression in classical Hodgkin lymphoma: its more than NF-κB!

Kreher S, Cauchy P, Bonifer C, Mathas S.

Cytokine. 2015 Mar;72(1):115-7. doi: 10.1016/j.cyto.2014.12.012. No abstract available.

PMID:
25585876
18.

Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma.

Kreher S, Bouhlel MA, Cauchy P, Lamprecht B, Li S, Grau M, Hummel F, Köchert K, Anagnostopoulos I, Jöhrens K, Hummel M, Hiscott J, Wenzel SS, Lenz P, Schneider M, Küppers R, Scheidereit C, Giefing M, Siebert R, Rajewsky K, Lenz G, Cockerill PN, Janz M, Dörken B, Bonifer C, Mathas S.

Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4513-22. doi: 10.1073/pnas.1406985111.

19.

Identification of a dynamic core transcriptional network in t(8;21) AML that regulates differentiation block and self-renewal.

Ptasinska A, Assi SA, Martinez-Soria N, Imperato MR, Piper J, Cauchy P, Pickin A, James SR, Hoogenkamp M, Williamson D, Wu M, Tenen DG, Ott S, Westhead DR, Cockerill PN, Heidenreich O, Bonifer C.

Cell Rep. 2014 Sep 25;8(6):1974-88. doi: 10.1016/j.celrep.2014.08.024.

20.

RUNX1 positively regulates a cell adhesion and migration program in murine hemogenic endothelium prior to blood emergence.

Lie-A-Ling M, Marinopoulou E, Li Y, Patel R, Stefanska M, Bonifer C, Miller C, Kouskoff V, Lacaud G.

Blood. 2014 Sep 11;124(11):e11-20. doi: 10.1182/blood-2014-04-572958.

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