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Items: 12


The small GTPases Ras and Rap1 bind to and control TORC2 activity.

Khanna A, Lotfi P, Chavan AJ, Montaño NM, Bolourani P, Weeks G, Shen Z, Briggs SP, Pots H, Van Haastert PJ, Kortholt A, Charest PG.

Sci Rep. 2016 May 13;6:25823. doi: 10.1038/srep25823.


Regulation of a LATS-homolog by Ras GTPases is important for the control of cell division.

Müller-Taubenberger A, Kastner PM, Schleicher M, Bolourani P, Weeks G.

BMC Cell Biol. 2014 Jul 1;15:25. doi: 10.1186/1471-2121-15-25.


RasG signaling is important for optimal folate chemotaxis in Dictyostelium.

Chattwood A, Bolourani P, Weeks G.

BMC Cell Biol. 2014 Apr 17;15:13. doi: 10.1186/1471-2121-15-13.


Developmental lineage priming in Dictyostelium by heterogeneous Ras activation.

Chattwood A, Nagayama K, Bolourani P, Harkin L, Kamjoo M, Weeks G, Thompson CR.

Elife. 2013 Nov 26;2:e01067. doi: 10.7554/eLife.01067.


Two distinct functions for PI3-kinases in macropinocytosis.

Hoeller O, Bolourani P, Clark J, Stephens LR, Hawkins PT, Weiner OD, Weeks G, Kay RR.

J Cell Sci. 2013 Sep 15;126(Pt 18):4296-307. doi: 10.1242/jcs.134015.


Determinants of RasC specificity during Dictyostelium aggregation.

Bolourani P, Spiegelman G, Weeks G.

J Biol Chem. 2010 Dec 31;285(53):41374-9. doi: 10.1074/jbc.M110.181115.


Ras proteins have multiple functions in vegetative cells of Dictyostelium.

Bolourani P, Spiegelman G, Weeks G.

Eukaryot Cell. 2010 Nov;9(11):1728-33. doi: 10.1128/EC.00141-10.


A Rap/phosphatidylinositol 3-kinase pathway controls pseudopod formation [corrected].

Kortholt A, Bolourani P, Rehmann H, Keizer-Gunnink I, Weeks G, Wittinghofer A, Van Haastert PJ.

Mol Biol Cell. 2010 Mar 15;21(6):936-45. doi: 10.1091/mbc.E09-03-0177. Erratum in: Mol Biol Cell. 2010 Apr;21(7):1314.


Regulation of Rap1 activity is required for differential adhesion, cell-type patterning and morphogenesis in Dictyostelium.

Parkinson K, Bolourani P, Traynor D, Aldren NL, Kay RR, Weeks G, Thompson CR.

J Cell Sci. 2009 Feb 1;122(Pt 3):335-44. doi: 10.1242/jcs.036822.


PIP3-independent activation of TorC2 and PKB at the cell's leading edge mediates chemotaxis.

Kamimura Y, Xiong Y, Iglesias PA, Hoeller O, Bolourani P, Devreotes PN.

Curr Biol. 2008 Jul 22;18(14):1034-43. doi: 10.1016/j.cub.2008.06.068.


Rap1 activation in response to cAMP occurs downstream of ras activation during Dictyostelium aggregation.

Bolourani P, Spiegelman GB, Weeks G.

J Biol Chem. 2008 Apr 18;283(16):10232-40. doi: 10.1074/jbc.M707459200.

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