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Items: 1 to 20 of 69

1.

Rapid genetic adaptation during the first four months of survival under resource exhaustion.

Avrani S, Bolotin E, Katz S, Hershberg R.

Mol Biol Evol. 2017 Mar 28. doi: 10.1093/molbev/msx118. [Epub ahead of print]

PMID:
28369614
2.

Bacterial intra-species gene loss occurs in a largely clocklike manner mostly within a pool of less conserved and constrained genes.

Bolotin E, Hershberg R.

Sci Rep. 2016 Oct 13;6:35168. doi: 10.1038/srep35168.

PMID:
27734920
3.

Hydrophobic-core PEGylated graft copolymer-stabilized nanoparticles composed of insoluble non-nucleoside reverse transcriptase inhibitors exhibit strong anti-HIV activity.

Leporati A, Novikov MS, Valuev-Elliston VT, Korolev SP, Khandazhinskaya AL, Kochetkov SN, Gupta S, Goding J, Bolotin E, Gottikh MB, Bogdanov AA Jr.

Nanomedicine. 2016 Nov;12(8):2405-2413. doi: 10.1016/j.nano.2016.07.004. Epub 2016 Jul 25.

PMID:
27456163
4.

Opposing roles of nuclear receptor HNF4α isoforms in colitis and colitis-associated colon cancer.

Chellappa K, Deol P, Evans JR, Vuong LM, Chen G, Briançon N, Bolotin E, Lytle C, Nair MG, Sladek FM.

Elife. 2016 May 11;5. pii: e10903. doi: 10.7554/eLife.10903.

PMID:
27166517
5.

A randomized, placebo-controlled, phase 1/2 study of tivantinib (ARQ 197) in combination with irinotecan and cetuximab in patients with metastatic colorectal cancer with wild-type KRAS who have received first-line systemic therapy.

Eng C, Bessudo A, Hart LL, Severtsev A, Gladkov O, Müller L, Kopp MV, Vladimirov V, Langdon R, Kotiv B, Barni S, Hsu C, Bolotin E, von Roemeling R, Schwartz B, Bendell JC.

Int J Cancer. 2016 Jul 1;139(1):177-86. doi: 10.1002/ijc.30049. Epub 2016 Mar 22.

PMID:
26891420
6.

Differential Effects of Hepatocyte Nuclear Factor 4α Isoforms on Tumor Growth and T-Cell Factor 4/AP-1 Interactions in Human Colorectal Cancer Cells.

Vuong LM, Chellappa K, Dhahbi JM, Deans JR, Fang B, Bolotin E, Titova NV, Hoverter NP, Spindler SR, Waterman ML, Sladek FM.

Mol Cell Biol. 2015 Oct;35(20):3471-90. doi: 10.1128/MCB.00030-15. Epub 2015 Aug 3.

PMID:
26240283
7.

Gene Loss Dominates As a Source of Genetic Variation within Clonal Pathogenic Bacterial Species.

Bolotin E, Hershberg R.

Genome Biol Evol. 2015 Jul 10;7(8):2173-87. doi: 10.1093/gbe/evv135.

PMID:
26163675
8.

Prediction of LDL cholesterol response to statin using transcriptomic and genetic variation.

Kim K, Bolotin E, Theusch E, Huang H, Medina MW, Krauss RM.

Genome Biol. 2014 Sep 30;15(9):460. doi: 10.1186/s13059-014-0460-9.

PMID:
25316374
9.

Statin-induced changes in gene expression in EBV-transformed and native B-cells.

Bolotin E, Armendariz A, Kim K, Heo SJ, Boffelli D, Tantisira K, Rotter JI, Krauss RM, Medina MW.

Hum Mol Genet. 2014 Mar 1;23(5):1202-10. doi: 10.1093/hmg/ddt512. Epub 2013 Oct 30.

PMID:
24179175
10.

Omeprazole and PGC-formulated heparin binding epidermal growth factor normalizes fasting blood glucose and suppresses insulitis in multiple low dose streptozotocin diabetes model.

Castillo GM, Nishimoto-Ashfield A, Banerjee AA, Landolfi JA, Lyubimov AV, Bolotin EM.

Pharm Res. 2013 Nov;30(11):2843-54. doi: 10.1007/s11095-013-1112-6. Epub 2013 Jun 21.

PMID:
23793991
11.

Protected graft copolymer excipient leads to a higher acute maximum tolerated dose and extends residence time of vasoactive intestinal Peptide significantly better than sterically stabilized micelles.

Reichstetter S, Castillo GM, Rubinstein I, Nishimoto-Ashfield A, Lai M, Jones CC, Banerjee AA, Lyubimov A, Bloedow DC, Bogdanov A Jr, Bolotin EM.

Pharm Res. 2013 Mar;30(3):670-82. doi: 10.1007/s11095-012-0904-4. Epub 2012 Dec 7. Erratum in: Pharm Res. 2013 Jul;30(7):1939. Banjeree, Aryamitra [corrected to Banerjee, Aryamitra A].

PMID:
23224976
12.

Protected Graft Copolymer (PGC) in Imaging and Therapy: A Platform for the Delivery of Covalently and Non-Covalently Bound Drugs.

Bogdanov AA Jr, Mazzanti M, Castillo G, Bolotin E.

Theranostics. 2012;2(6):553-76. doi: 10.7150/thno.4070. Epub 2012 Jun 4.

PMID:
22737192
13.

The transcription factor encyclopedia.

Yusuf D, Butland SL, Swanson MI, Bolotin E, Ticoll A, Cheung WA, Zhang XY, Dickman CT, Fulton DL, Lim JS, Schnabl JM, Ramos OH, Vasseur-Cognet M, de Leeuw CN, Simpson EM, Ryffel GU, Lam EW, Kist R, Wilson MS, Marco-Ferreres R, Brosens JJ, Beccari LL, Bovolenta P, Benayoun BA, Monteiro LJ, Schwenen HD, Grontved L, Wederell E, Mandrup S, Veitia RA, Chakravarthy H, Hoodless PA, Mancarelli MM, Torbett BE, Banham AH, Reddy SP, Cullum RL, Liedtke M, Tschan MP, Vaz M, Rizzino A, Zannini M, Frietze S, Farnham PJ, Eijkelenboom A, Brown PJ, Laperrière D, Leprince D, de Cristofaro T, Prince KL, Putker M, del Peso L, Camenisch G, Wenger RH, Mikula M, Rozendaal M, Mader S, Ostrowski J, Rhodes SJ, Van Rechem C, Boulay G, Olechnowicz SW, Breslin MB, Lan MS, Nanan KK, Wegner M, Hou J, Mullen RD, Colvin SC, Noy PJ, Webb CF, Witek ME, Ferrell S, Daniel JM, Park J, Waldman SA, Peet DJ, Taggart M, Jayaraman PS, Karrich JJ, Blom B, Vesuna F, O'Geen H, Sun Y, Gronostajski RM, Woodcroft MW, Hough MR, Chen E, Europe-Finner GN, Karolczak-Bayatti M, Bailey J, Hankinson O, Raman V, LeBrun DP, Biswal S, Harvey CJ, DeBruyne JP, Hogenesch JB, Hevner RF, Héligon C, Luo XM, Blank MC, Millen KJ, Sharlin DS, Forrest D, Dahlman-Wright K, Zhao C, Mishima Y, Sinha S, Chakrabarti R, Portales-Casamar E, Sladek FM, Bradley PH, Wasserman WW.

Genome Biol. 2012;13(3):R24. doi: 10.1186/gb-2012-13-3-r24.

PMID:
22458515
14.

Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors.

Fang B, Mane-Padros D, Bolotin E, Jiang T, Sladek FM.

Nucleic Acids Res. 2012 Jul;40(12):5343-56. doi: 10.1093/nar/gks190. Epub 2012 Mar 1.

PMID:
22383578
15.

Protected graft copolymer (PGC) basal formulation of insulin as potentially safer alternative to Lantus® (insulin-glargine): a streptozotocin-induced, diabetic Sprague Dawley rats study.

Reichstetter S, Castillo GM, Lai M, Nishimoto-Ashfield A, Banerjee A, Bogdanov A, Lyubimov AV, Bolotin EM.

Pharm Res. 2012 Apr;29(4):1033-9. doi: 10.1007/s11095-011-0646-8. Epub 2011 Dec 28.

PMID:
22203325
16.

Nuclear receptor HNF4α binding sequences are widespread in Alu repeats.

Bolotin E, Chellappa K, Hwang-Verslues W, Schnabl JM, Yang C, Sladek FM.

BMC Genomics. 2011 Nov 15;12:560. doi: 10.1186/1471-2164-12-560.

PMID:
22085832
17.

Imaging the pancreatic vasculature in diabetes models.

Medarova Z, Greiner DL, Ifediba M, Dai G, Bolotin E, Castillo G, Bogdanov A, Kumar M, Moore A.

Diabetes Metab Res Rev. 2011 Nov;27(8):767-72. doi: 10.1002/dmrr.1249.

PMID:
22069257
18.

The noncoding RNA Mistral activates Hoxa6 and Hoxa7 expression and stem cell differentiation by recruiting MLL1 to chromatin.

Bertani S, Sauer S, Bolotin E, Sauer F.

Mol Cell. 2011 Sep 16;43(6):1040-6. doi: 10.1016/j.molcel.2011.08.019. Retraction in: Mol Cell. 2015 Feb 5;57(3):572.

PMID:
21925392
19.

Extending residence time and stability of peptides by protected graft copolymer (PGC) excipient: GLP-1 example.

Castillo GM, Reichstetter S, Bolotin EM.

Pharm Res. 2012 Jan;29(1):306-18. doi: 10.1007/s11095-011-0542-2. Epub 2011 Aug 4.

PMID:
21830140
20.

Transplant-associated thrombotic microangiopathy in pediatric patients treated with sirolimus and tacrolimus.

Rosenthal J, Pawlowska A, Bolotin E, Cervantes C, Maroongroge S, Thomas SH, Forman SJ.

Pediatr Blood Cancer. 2011 Jul 15;57(1):142-6. doi: 10.1002/pbc.22861. Epub 2010 Nov 23.

PMID:
21557459

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