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Items: 1 to 20 of 74

1.

Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes.

Look AHEAD Research Group, Wing RR, Bolin P, Brancati FL, Bray GA, Clark JM, Coday M, Crow RS, Curtis JM, Egan CM, Espeland MA, Evans M, Foreyt JP, Ghazarian S, Gregg EW, Harrison B, Hazuda HP, Hill JO, Horton ES, Hubbard VS, Jakicic JM, Jeffery RW, Johnson KC, Kahn SE, Kitabchi AE, Knowler WC, Lewis CE, Maschak-Carey BJ, Montez MG, Murillo A, Nathan DM, Patricio J, Peters A, Pi-Sunyer X, Pownall H, Reboussin D, Regensteiner JG, Rickman AD, Ryan DH, Safford M, Wadden TA, Wagenknecht LE, West DS, Williamson DF, Yanovski SZ.

N Engl J Med. 2013 Jul 11;369(2):145-54. doi: 10.1056/NEJMoa1212914. Epub 2013 Jun 24. Erratum in: N Engl J Med. 2014 May 8;370(19):1866.

2.

Osmolyte effects on protein stability and solubility: a balancing act between backbone and side-chains.

Auton M, Rösgen J, Sinev M, Holthauzen LM, Bolen DW.

Biophys Chem. 2011 Nov;159(1):90-9. doi: 10.1016/j.bpc.2011.05.012. Epub 2011 May 19.

3.

Backbone additivity in the transfer model of protein solvation.

Hu CY, Kokubo H, Lynch GC, Bolen DW, Pettitt BM.

Protein Sci. 2010 May;19(5):1011-22. doi: 10.1002/pro.378.

4.

Hydrogen bonding progressively strengthens upon transfer of the protein urea-denatured state to water and protecting osmolytes.

Holthauzen LM, Rösgen J, Bolen DW.

Biochemistry. 2010 Feb 16;49(6):1310-8. doi: 10.1021/bi9015499.

5.

Osmolyte-induced conformational changes in the Hsp90 molecular chaperone.

Street TO, Krukenberg KA, Rosgen J, Bolen DW, Agard DA.

Protein Sci. 2010 Jan;19(1):57-65. doi: 10.1002/pro.282.

6.

Rational modulation of conformational fluctuations in adenylate kinase reveals a local unfolding mechanism for allostery and functional adaptation in proteins.

Schrank TP, Bolen DW, Hilser VJ.

Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):16984-9. doi: 10.1073/pnas.0906510106. Epub 2009 Sep 21.

7.

Structure and energetics of the hydrogen-bonded backbone in protein folding.

Bolen DW, Rose GD.

Annu Rev Biochem. 2008;77:339-62. doi: 10.1146/annurev.biochem.77.061306.131357. Review.

PMID:
18518824
8.

Structural thermodynamics of protein preferential solvation: osmolyte solvation of proteins, aminoacids, and peptides.

Auton M, Bolen DW, Rösgen J.

Proteins. 2008 Dec;73(4):802-13. doi: 10.1002/prot.22103.

PMID:
18498104
9.

Anatomy of energetic changes accompanying urea-induced protein denaturation.

Auton M, Holthauzen LM, Bolen DW.

Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15317-22. Epub 2007 Sep 18.

10.
11.

Effects of cell volume regulating osmolytes on glycerol 3-phosphate binding to triosephosphate isomerase.

Gulotta M, Qiu L, Desamero R, Rösgen J, Bolen DW, Callender R.

Biochemistry. 2007 Sep 4;46(35):10055-62. Epub 2007 Aug 15.

12.

Molecular basis of the apparent near ideality of urea solutions.

Kokubo H, Rösgen J, Bolen DW, Pettitt BM.

Biophys J. 2007 Nov 15;93(10):3392-407. Epub 2007 Aug 10.

13.

An analysis of the molecular origin of osmolyte-dependent protein stability.

Rösgen J, Pettitt BM, Bolen DW.

Protein Sci. 2007 Apr;16(4):733-43. Epub 2007 Feb 27.

14.

Mixed osmolytes: the degree to which one osmolyte affects the protein stabilizing ability of another.

Holthauzen LM, Bolen DW.

Protein Sci. 2007 Feb;16(2):293-8. Epub 2006 Dec 22.

15.

Protein phase diagrams II: nonideal behavior of biochemical reactions in the presence of osmolytes.

Ferreon AC, Ferreon JC, Bolen DW, Rösgen J.

Biophys J. 2007 Jan 1;92(1):245-56. Epub 2006 Oct 6.

16.

A molecular mechanism for osmolyte-induced protein stability.

Street TO, Bolen DW, Rose GD.

Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):13997-4002. Epub 2006 Sep 12. Erratum in: Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):17064.

17.

Metrics that differentiate the origins of osmolyte effects on protein stability: a test of the surface tension proposal.

Auton M, Ferreon AC, Bolen DW.

J Mol Biol. 2006 Sep 1;361(5):983-92. Epub 2006 Aug 4.

PMID:
16889793
18.

Osmolyte-induced protein folding free energy changes.

Wu P, Bolen DW.

Proteins. 2006 May 1;63(2):290-6.

PMID:
16453342
19.

Predicting the energetics of osmolyte-induced protein folding/unfolding.

Auton M, Bolen DW.

Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15065-8. Epub 2005 Oct 7.

20.

Novel use of an osmolyte to dissect multiple thermodynamic linkages in a chemokine ligand-receptor system.

Rajagopalan L, Rösgen J, Bolen DW, Rajarathnam K.

Biochemistry. 2005 Oct 4;44(39):12932-9.

PMID:
16185062

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