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Items: 1 to 20 of 35

1.

A System for an Accountable Data Analysis Process in R.

Gelfond J, Goros M, Hernandez B, Bokov A.

R J. 2018 Jul;10(1):6-21. Epub 2018 May 15.

2.

Estimate risk difference and number needed to treat in survival analysis.

Zhang Z, Ambrogi F, Bokov AF, Gu H, de Beurs E, Eskaf K.

Ann Transl Med. 2018 Apr;6(7):120. doi: 10.21037/atm.2018.01.36.

3.

DLK-1, SEK-3 and PMK-3 Are Required for the Life Extension Induced by Mitochondrial Bioenergetic Disruption in C. elegans.

Munkácsy E, Khan MH, Lane RK, Borror MB, Park JH, Bokov AF, Fisher AL, Link CD, Rea SL.

PLoS Genet. 2016 Jul 15;12(7):e1006133. doi: 10.1371/journal.pgen.1006133. eCollection 2016 Jul.

4.

Liver specific expression of Cu/ZnSOD extends the lifespan of Sod1 null mice.

Zhang Y, Liu Y, Walsh M, Bokov A, Ikeno Y, Jang YC, Perez VI, Van Remmen H, Richardson A.

Mech Ageing Dev. 2016 Mar;154:1-8. doi: 10.1016/j.mad.2016.01.005. Epub 2016 Feb 1.

5.

Mitochondrial metabolites extend lifespan.

Mishur RJ, Khan M, Munkácsy E, Sharma L, Bokov A, Beam H, Radetskaya O, Borror M, Lane R, Bai Y, Rea SL.

Aging Cell. 2016 Apr;15(2):336-48. doi: 10.1111/acel.12439. Epub 2016 Jan 5.

6.

Rapamycin Increases Mortality in db/db Mice, a Mouse Model of Type 2 Diabetes.

Sataranatarajan K, Ikeno Y, Bokov A, Feliers D, Yalamanchili H, Lee HJ, Mariappan MM, Tabatabai-Mir H, Diaz V, Prasad S, Javors MA, Ghosh Choudhury G, Hubbard GB, Barnes JL, Richardson A, Kasinath BS.

J Gerontol A Biol Sci Med Sci. 2016 Jul;71(7):850-7. doi: 10.1093/gerona/glv170. Epub 2015 Oct 5.

7.

Rapamycin improves motor function, reduces 4-hydroxynonenal adducted protein in brain, and attenuates synaptic injury in a mouse model of synucleinopathy.

Bai X, Wey MC, Fernandez E, Hart MJ, Gelfond J, Bokov AF, Rani S, Strong R.

Pathobiol Aging Age Relat Dis. 2015 Aug 24;5:28743. doi: 10.3402/pba.v5.28743. eCollection 2015.

8.

Short-term rapamycin treatment in mice has few effects on the transcriptome of white adipose tissue compared to dietary restriction.

Fok WC, Livi C, Bokov A, Yu Z, Chen Y, Richardson A, Pérez VI.

Mech Ageing Dev. 2014 Sep;140:23-9. doi: 10.1016/j.mad.2014.07.004. Epub 2014 Jul 27.

9.

Negative elongation factor controls energy homeostasis in cardiomyocytes.

Pan H, Qin K, Guo Z, Ma Y, April C, Gao X, Andrews TG, Bokov A, Zhang J, Chen Y, Weintraub ST, Fan JB, Wang D, Hu Y, Aune GJ, Lindsey ML, Li R.

Cell Rep. 2014 Apr 10;7(1):79-85. doi: 10.1016/j.celrep.2014.02.028. Epub 2014 Mar 20.

10.

Mice fed rapamycin have an increase in lifespan associated with major changes in the liver transcriptome.

Fok WC, Chen Y, Bokov A, Zhang Y, Salmon AB, Diaz V, Javors M, Wood WH 3rd, Zhang Y, Becker KG, Pérez VI, Richardson A.

PLoS One. 2014 Jan 7;9(1):e83988. doi: 10.1371/journal.pone.0083988. eCollection 2014. Erratum in: PLoS One. 2014;9(4):e92346.

11.

Combined treatment of rapamycin and dietary restriction has a larger effect on the transcriptome and metabolome of liver.

Fok WC, Bokov A, Gelfond J, Yu Z, Zhang Y, Doderer M, Chen Y, Javors M, Wood WH 3rd, Zhang Y, Becker KG, Richardson A, Pérez VI.

Aging Cell. 2014 Apr;13(2):311-9. doi: 10.1111/acel.12175. Epub 2013 Dec 5.

12.

Decreased in vitro mitochondrial function is associated with enhanced brain metabolism, blood flow, and memory in Surf1-deficient mice.

Lin AL, Pulliam DA, Deepa SS, Halloran JJ, Hussong SA, Burbank RR, Bresnen A, Liu Y, Podlutskaya N, Soundararajan A, Muir E, Duong TQ, Bokov AF, Viscomi C, Zeviani M, Richardson AG, Van Remmen H, Fox PT, Galvan V.

J Cereb Blood Flow Metab. 2013 Oct;33(10):1605-11. doi: 10.1038/jcbfm.2013.116. Epub 2013 Jul 10.

13.

Rapamycin extends life and health in C57BL/6 mice.

Zhang Y, Bokov A, Gelfond J, Soto V, Ikeno Y, Hubbard G, Diaz V, Sloane L, Maslin K, Treaster S, Réndon S, van Remmen H, Ward W, Javors M, Richardson A, Austad SN, Fischer K.

J Gerontol A Biol Sci Med Sci. 2014 Feb;69(2):119-30. doi: 10.1093/gerona/glt056. Epub 2013 May 16.

14.

Dietary restriction attenuates the accelerated aging phenotype of Sod1(-/-) mice.

Zhang Y, Ikeno Y, Bokov A, Gelfond J, Jaramillo C, Zhang HM, Liu Y, Qi W, Hubbard G, Richardson A, Van Remmen H.

Free Radic Biol Med. 2013 Jul;60:300-6. doi: 10.1016/j.freeradbiomed.2013.02.026. Epub 2013 Feb 28.

15.

Rapamycin extends life span of Rb1+/- mice by inhibiting neuroendocrine tumors.

Livi CB, Hardman RL, Christy BA, Dodds SG, Jones D, Williams C, Strong R, Bokov A, Javors MA, Ikeno Y, Hubbard G, Hasty P, Sharp ZD.

Aging (Albany NY). 2013 Feb;5(2):100-10.

16.

Probing the relationship between insulin sensitivity and longevity using genetically modified mice.

Nelson JF, Strong R, Bokov A, Diaz V, Ward W.

J Gerontol A Biol Sci Med Sci. 2012 Dec;67(12):1332-8. doi: 10.1093/gerona/gls199. Epub 2012 Oct 22.

17.

Profiling the anaerobic response of C. elegans using GC-MS.

Butler JA, Mishur RJ, Bokov AF, Hakala KW, Weintraub ST, Rea SL.

PLoS One. 2012;7(9):e46140. doi: 10.1371/journal.pone.0046140. Epub 2012 Sep 27.

18.

Rapamycin selectively alters serum chemistry in diabetic mice.

Tabatabai-Mir H, Sataranatarajan K, Lee HJ, Bokov AF, Fernandez E, Diaz V, Choudhury GG, Richardson A, Kasinath BS.

Pathobiol Aging Age Relat Dis. 2012;2. doi: 10.3402/pba.v2i0.15896. Epub 2012 Apr 23.

19.

Effects of diet on synaptic vesicle release in dynactin complex mutants: a mechanism for improved vitality during motor disease.

Rawson JM, Kreko T, Davison H, Mahoney R, Bokov A, Chang L, Gelfond J, Macleod GT, Eaton BA.

Aging Cell. 2012 Jun;11(3):418-27. doi: 10.1111/j.1474-9726.2012.00799.x. Epub 2012 Feb 22.

20.

Does reduced IGF-1R signaling in Igf1r+/- mice alter aging?

Bokov AF, Garg N, Ikeno Y, Thakur S, Musi N, DeFronzo RA, Zhang N, Erickson RC, Gelfond J, Hubbard GB, Adamo ML, Richardson A.

PLoS One. 2011;6(11):e26891. doi: 10.1371/journal.pone.0026891. Epub 2011 Nov 23.

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