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Items: 1 to 20 of 79

1.

The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation.

Kulak K, Westermark GT, Papac-Milicevic N, Renström E, Blom AM, King BC.

Diabetologia. 2017 Aug;60(8):1522-1533. doi: 10.1007/s00125-017-4286-3. Epub 2017 May 12.

2.

Analysis of complement biomarkers in systemic sclerosis indicates a distinct pattern in scleroderma renal crisis.

Okrój M, Johansson M, Saxne T, Blom AM, Hesselstrand R.

Arthritis Res Ther. 2016 Nov 18;18(1):267.

3.

A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug-induced liver injury and postinjury inflammation in mice.

Lundbäck P, Lea JD, Sowinska A, Ottosson L, Fürst CM, Steen J, Aulin C, Clarke JI, Kipar A, Klevenvall L, Yang H, Palmblad K, Park BK, Tracey KJ, Blom AM, Andersson U, Antoine DJ, Erlandsson Harris H.

Hepatology. 2016 Nov;64(5):1699-1710. doi: 10.1002/hep.28736. Epub 2016 Sep 1.

4.

Complement inhibitor CSMD1 acts as tumor suppressor in human breast cancer.

Escudero-Esparza A, Bartoschek M, Gialeli C, Okroj M, Owen S, Jirström K, Orimo A, Jiang WG, Pietras K, Blom AM.

Oncotarget. 2016 Nov 22;7(47):76920-76933. doi: 10.18632/oncotarget.12729.

5.

The complement system is activated in synovial fluid from subjects with knee injury and from patients with osteoarthritis.

Struglics A, Okroj M, Swärd P, Frobell R, Saxne T, Lohmander LS, Blom AM.

Arthritis Res Ther. 2016 Oct 6;18(1):223.

6.

Testing the Activity of Complement Convertases in Serum/Plasma for Diagnosis of C4NeF-Mediated C3 Glomerulonephritis.

Blom AM, Corvillo F, Magda M, Stasiłojć G, Nozal P, Pérez-Valdivia MÁ, Cabello-Chaves V, Rodríguez de Córdoba S, López-Trascasa M, Okrój M.

J Clin Immunol. 2016 Jul;36(5):517-27. doi: 10.1007/s10875-016-0290-5. Epub 2016 May 5.

7.

Moonlighting of Helicobacter pylori catalase protects against complement-mediated killing by utilising the host molecule vitronectin.

Richter C, Mukherjee O, Ermert D, Singh B, Su YC, Agarwal V, Blom AM, Riesbeck K.

Sci Rep. 2016 Apr 18;6:24391. doi: 10.1038/srep24391.

8.

Factor H uptake regulates intracellular C3 activation during apoptosis and decreases the inflammatory potential of nucleosomes.

Martin M, Leffler J, Smoląg KI, Mytych J, Björk A, Chaves LD, Alexander JJ, Quigg RJ, Blom AM.

Cell Death Differ. 2016 May;23(5):903-11. doi: 10.1038/cdd.2015.164. Epub 2016 Jan 15.

9.

CD46 Activation Regulates miR-150-Mediated Control of GLUT1 Expression and Cytokine Secretion in Human CD4+ T Cells.

King BC, Esguerra JL, Golec E, Eliasson L, Kemper C, Blom AM.

J Immunol. 2016 Feb 15;196(4):1636-45. doi: 10.4049/jimmunol.1500516. Epub 2016 Jan 8.

10.

Correction: Fine Mapping of the Interaction between C4b-Binding Protein and Outer Membrane Proteins LigA and LigB of Pathogenic Leptospira interrogans.

Breda LC, Hsieh CL, Castiblanco Valencia MM, da Silva LB, Barbosa AS, Blom AM, Chang YF, Isaac L.

PLoS Negl Trop Dis. 2015 Dec 4;9(12):e0004286. doi: 10.1371/journal.pntd.0004286. eCollection 2015 Dec. No abstract available.

11.

Fine Mapping of the Interaction between C4b-Binding Protein and Outer Membrane Proteins LigA and LigB of Pathogenic Leptospira interrogans.

Breda LC, Hsieh CL, Castiblanco Valencia MM, da Silva LB, Barbosa AS, Blom AM, Chang YF, Isaac L.

PLoS Negl Trop Dis. 2015 Oct 30;9(10):e0004192. doi: 10.1371/journal.pntd.0004192. eCollection 2015. Erratum in: PLoS Negl Trop Dis. 2015 Dec;9(12):e0004286. Yung-Fu, Chang [corrected to Chang, Yung-Fu].

12.

The human complement inhibitor Sushi Domain-Containing Protein 4 (SUSD4) expression in tumor cells and infiltrating T cells is associated with better prognosis of breast cancer patients.

Englund E, Reitsma B, King BC, Escudero-Esparza A, Owen S, Orimo A, Okroj M, Anagnostaki L, Jiang WG, Jirström K, Blom AM.

BMC Cancer. 2015 Oct 19;15:737. doi: 10.1186/s12885-015-1734-7.

13.

A subset of patients with systemic lupus erythematosus fails to degrade DNA from multiple clinically relevant sources.

Leffler J, Ciacma K, Gullstrand B, Bengtsson AA, Martin M, Blom AM.

Arthritis Res Ther. 2015 Aug 13;17:205. doi: 10.1186/s13075-015-0726-y.

14.

A Metalloproteinase Mirolysin of Tannerella forsythia Inhibits All Pathways of the Complement System.

Jusko M, Potempa J, Mizgalska D, Bielecka E, Ksiazek M, Riesbeck K, Garred P, Eick S, Blom AM.

J Immunol. 2015 Sep 1;195(5):2231-40. doi: 10.4049/jimmunol.1402892. Epub 2015 Jul 24.

15.

Virulence of Group A Streptococci Is Enhanced by Human Complement Inhibitors.

Ermert D, Shaughnessy J, Joeris T, Kaplan J, Pang CJ, Kurt-Jones EA, Rice PA, Ram S, Blom AM.

PLoS Pathog. 2015 Jul 22;11(7):e1005043. doi: 10.1371/journal.ppat.1005043. eCollection 2015 Jul.

16.

A Novel Interaction between Complement Inhibitor C4b-binding Protein and Plasminogen That Enhances Plasminogen Activation.

Agarwal V, Talens S, Grandits AM, Blom AM.

J Biol Chem. 2015 Jul 24;290(30):18333-42. doi: 10.1074/jbc.M114.619494. Epub 2015 Jun 11.

17.

Zinc supplementation inhibits complement activation in age-related macular degeneration.

Smailhodzic D, van Asten F, Blom AM, Mohlin FC, den Hollander AI, van de Ven JP, van Huet RA, Groenewoud JM, Tian Y, Berendschot TT, Lechanteur YT, Fauser S, de Bruijn C, Daha MR, van der Wilt GJ, Hoyng CB, Klevering BJ.

PLoS One. 2014 Nov 13;9(11):e112682. doi: 10.1371/journal.pone.0112682. eCollection 2014.

18.

Peptidyl arginine deiminase from Porphyromonas gingivalis abolishes anaphylatoxin C5a activity.

Bielecka E, Scavenius C, Kantyka T, Jusko M, Mizgalska D, Szmigielski B, Potempa B, Enghild JJ, Prossnitz ER, Blom AM, Potempa J.

J Biol Chem. 2014 Nov 21;289(47):32481-7. doi: 10.1074/jbc.C114.617142. Epub 2014 Oct 16.

19.

Streptococcus pneumoniae phosphoglycerate kinase is a novel complement inhibitor affecting the membrane attack complex formation.

Blom AM, Bergmann S, Fulde M, Riesbeck K, Agarwal V.

J Biol Chem. 2014 Nov 21;289(47):32499-511. doi: 10.1074/jbc.M114.610212. Epub 2014 Oct 3.

20.

Carbamylation of immunoglobulin abrogates activation of the classical complement pathway.

Koro C, Bielecka E, Dahl-Knudsen A, Enghild JJ, Scavenius C, Brun JG, Binder V, Hellvard A, Bergum B, Jonsson R, Potempa J, Blom AM, Mydel P.

Eur J Immunol. 2014 Nov;44(11):3403-12. doi: 10.1002/eji.201444869. Epub 2014 Oct 20.

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