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Items: 1 to 20 of 218


Tyro3, Axl, and Mertk receptors differentially participate in platelet activation and thrombus formation.

Zhou J, Yang A, Wang Y, Chen F, Zhao Z, Davra V, Suzuki-Inoue K, Ozaki Y, Birge RB, Lu Q, Wu Y.

Cell Commun Signal. 2018 Dec 12;16(1):98. doi: 10.1186/s12964-018-0308-0.


heZEB2, a master regulator of the epithelial-mesenchymal transition, mediates trophoblast differentiation.

DaSilva-Arnold S, Kuo CY, Davra V, Remache Y, Kim PCW, Fisher JP, Zamudio S, Al-Khan A, Birge RB, Illsley NP.

Mol Hum Reprod. 2018 Nov 21. doi: 10.1093/molehr/gay053. [Epub ahead of print]


Insulin-like growth factor receptor signaling in breast tumor epithelium protects cells from endoplasmic reticulum stress and regulates the tumor microenvironment.

Obr AE, Kumar S, Chang YJ, Bulatowicz JJ, Barnes BJ, Birge RB, Lazzarino DA, Gallagher E, LeRoith D, Wood TL.

Breast Cancer Res. 2018 Nov 20;20(1):138. doi: 10.1186/s13058-018-1063-2.


MerTK signaling in macrophages promotes the synthesis of inflammation resolution mediators by suppressing CaMKII activity.

Cai B, Kasikara C, Doran AC, Ramakrishnan R, Birge RB, Tabas I.

Sci Signal. 2018 Sep 25;11(549). pii: eaar3721. doi: 10.1126/scisignal.aar3721.


International conference on Cell Death in Cancer and Toxicology 2018 (CDCT-2018).

Ansari KM, Arany PR, Arama E, Larisch S, Birge RB, Chandra D.

Cell Commun Signal. 2018 Jun 28;16(1):34. doi: 10.1186/s12964-018-0238-x.


Light Harvesting by Equally Contributing Mechanisms in a Photosynthetic Antenna Protein.

Guberman-Pfeffer MJ, Greco JA, Birge RR, Frank HA, Gascón JA.

J Phys Chem Lett. 2018 Feb 1;9(3):563-568. doi: 10.1021/acs.jpclett.7b03211. Epub 2018 Jan 19.


Crk adaptor protein promotes PD-L1 expression, EMT and immune evasion in a murine model of triple-negative breast cancer.

Kumar S, Davra V, Obr AE, Geng K, Wood TL, De Lorenzo MS, Birge RB.

Oncoimmunology. 2017 Sep 27;7(1):e1376155. doi: 10.1080/2162402X.2017.1376155. eCollection 2017. Erratum in: Oncoimmunology. 2017 Dec 19;7(1):e1413845.


The Forbidden 11Bu- Excited Singlet State in Peridinin and Peridinin Analogues.

Greco JA, Wagner NL, Frank HA, Birge RR.

J Phys Chem A. 2018 Jan 11;122(1):130-139. doi: 10.1021/acs.jpca.7b10001. Epub 2017 Dec 19.


Requirement of Gamma-Carboxyglutamic Acid Modification and Phosphatidylserine Binding for the Activation of Tyro3, Axl, and Mertk Receptors by Growth Arrest-Specific 6.

Geng K, Kumar S, Kimani SG, Kholodovych V, Kasikara C, Mizuno K, Sandiford O, Rameshwar P, Kotenko SV, Birge RB.

Front Immunol. 2017 Nov 10;8:1521. doi: 10.3389/fimmu.2017.01521. eCollection 2017.


Efferocytosis of dying cells differentially modulate immunological outcomes in tumor microenvironment.

Kumar S, Calianese D, Birge RB.

Immunol Rev. 2017 Nov;280(1):149-164. doi: 10.1111/imr.12587. Review.


The Procoagulant Activity of Apoptotic Cells Is Mediated by Interaction with Factor XII.

Yang A, Chen F, He C, Zhou J, Lu Y, Dai J, Birge RB, Wu Y.

Front Immunol. 2017 Sep 25;8:1188. doi: 10.3389/fimmu.2017.01188. eCollection 2017.


Crk Tyrosine Phosphorylation Regulates PDGF-BB-inducible Src Activation and Breast Tumorigenicity and Metastasis.

Kumar S, Lu B, Davra V, Hornbeck P, Machida K, Birge RB.

Mol Cancer Res. 2018 Jan;16(1):173-183. doi: 10.1158/1541-7786.MCR-17-0242. Epub 2017 Oct 3.


Expression, purification, and spectral tuning of RhoGC, a retinylidene/guanylyl cyclase fusion protein and optogenetics tool from the aquatic fungus Blastocladiella emersonii.

Trieu MM, Devine EL, Lamarche LB, Ammerman AE, Greco JA, Birge RR, Theobald DL, Oprian DD.

J Biol Chem. 2017 Jun 23;292(25):10379-10389. doi: 10.1074/jbc.M117.789636. Epub 2017 May 4.


Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicity.

Kimani SG, Kumar S, Bansal N, Singh K, Kholodovych V, Comollo T, Peng Y, Kotenko SV, Sarafianos SG, Bertino JR, Welsh WJ, Birge RB.

Sci Rep. 2017 Mar 8;7:43908. doi: 10.1038/srep43908.


Phosphatidylserine Sensing by TAM Receptors Regulates AKT-Dependent Chemoresistance and PD-L1 Expression.

Kasikara C, Kumar S, Kimani S, Tsou WI, Geng K, Davra V, Sriram G, Devoe C, Nguyen KN, Antes A, Krantz A, Rymarczyk G, Wilczynski A, Empig C, Freimark B, Gray M, Schlunegger K, Hutchins J, Kotenko SV, Birge RB.

Mol Cancer Res. 2017 Jun;15(6):753-764. doi: 10.1158/1541-7786.MCR-16-0350. Epub 2017 Feb 9.


Bacteriochlorins with a Twist: Discovery of a Unique Mechanism to Red-Shift the Optical Spectra of Bacteriochlorins.

Guberman-Pfeffer MJ, Greco JA, Samankumara LP, Zeller M, Birge RR, Gascón JA, Brückner C.

J Am Chem Soc. 2017 Jan 11;139(1):548-560. doi: 10.1021/jacs.6b12419. Epub 2016 Dec 20.


Ligand Activation of TAM Family Receptors-Implications for Tumor Biology and Therapeutic Response.

Davra V, Kimani SG, Calianese D, Birge RB.

Cancers (Basel). 2016 Nov 29;8(12). pii: E107. Review.


Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase.

Kimani SG, Kumar S, Davra V, Chang YJ, Kasikara C, Geng K, Tsou WI, Wang S, Hoque M, Boháč A, Lewis-Antes A, De Lorenzo MS, Kotenko SV, Birge RB.

Cell Commun Signal. 2016 Sep 6;14(1):19. doi: 10.1186/s12964-016-0142-1.



Kumar S, Birge RB.

Curr Biol. 2016 Jul 11;26(13):R558-R559. doi: 10.1016/j.cub.2016.01.059.


Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer.

Birge RB, Boeltz S, Kumar S, Carlson J, Wanderley J, Calianese D, Barcinski M, Brekken RA, Huang X, Hutchins JT, Freimark B, Empig C, Mercer J, Schroit AJ, Schett G, Herrmann M.

Cell Death Differ. 2016 Jun;23(6):962-78. doi: 10.1038/cdd.2016.11. Epub 2016 Feb 26. Review.

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