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Items: 13


Investigation of selective JAK1 inhibitor GSK2586184 for the treatment of psoriasis in a randomized placebo-controlled phase IIa study.

Ludbrook VJ, Hicks KJ, Hanrott KE, Patel JS, Binks MH, Wyres MR, Watson J, Wilson P, Simeoni M, Schifano LA, Reich K, Griffiths CE.

Br J Dermatol. 2016 May;174(5):985-95. doi: 10.1111/bjd.14399. Epub 2016 Apr 7.


A model of skin inflammation in humans leads to a rapid and reproducible increase in the interferon response signature: a potential translational model for drug development.

Dickson MC, Ludbrook VJ, Perry HC, Wilson PA, Garthside SJ, Binks MH.

Inflamm Res. 2015 Apr;64(3-4):171-83. doi: 10.1007/s00011-015-0795-z. Epub 2015 Jan 18.


Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci.

Vignal C, Bansal AT, Balding DJ, Binks MH, Dickson MC, Montgomery DS, Wilson AG.

Arthritis Rheum. 2009 Jan;60(1):53-62. doi: 10.1002/art.24138.


Evidence of epistasis between interleukin 1 and selenoprotein-S with susceptibility to rheumatoid arthritis.

Marinou I, Walters K, Dickson MC, Binks MH, Bax DE, Wilson AG.

Ann Rheum Dis. 2009 Sep;68(9):1494-7. doi: 10.1136/ard.2008.090001. Epub 2008 Aug 26.


Potential novel biomarkers of disease activity in rheumatoid arthritis patients: CXCL13, CCL23, transforming growth factor alpha, tumor necrosis factor receptor superfamily member 9, and macrophage colony-stimulating factor.

Rioja I, Hughes FJ, Sharp CH, Warnock LC, Montgomery DS, Akil M, Wilson AG, Binks MH, Dickson MC.

Arthritis Rheum. 2008 Aug;58(8):2257-67. doi: 10.1002/art.23667.


Association between radiographic severity of rheumatoid arthritis and shared epitope alleles: differing mechanisms of susceptibility and protection.

Mewar D, Marinou I, Coote AL, Moore DJ, Akil M, Smillie D, Dickson MC, Binks MH, Montgomery DS, Wilson AG.

Ann Rheum Dis. 2008 Jul;67(7):980-3. Epub 2007 Sep 27.


Association of interleukin-6 and interleukin-10 genotypes with radiographic damage in rheumatoid arthritis is dependent on autoantibody status.

Marinou I, Healy J, Mewar D, Moore DJ, Dickson MC, Binks MH, Montgomery DS, Walters K, Wilson AG.

Arthritis Rheum. 2007 Aug;56(8):2549-56.


The interferon induced with helicase domain 1 A946T polymorphism is not associated with rheumatoid arthritis.

Marinou I, Montgomery DS, Dickson MC, Binks MH, Moore DJ, Bax DE, Wilson AG.

Arthritis Res Ther. 2007;9(2):R40.


Independent associations of anti-cyclic citrullinated peptide antibodies and rheumatoid factor with radiographic severity of rheumatoid arthritis.

Mewar D, Coote A, Moore DJ, Marinou I, Keyworth J, Dickson MC, Montgomery DS, Binks MH, Wilson AG.

Arthritis Res Ther. 2006;8(4):R128.


Novel molecular mechanisms of dendritic cell-induced T cell activation.

Woodhead VE, Stonehouse TJ, Binks MH, Speidel K, Fox DA, Gaya A, Hardie D, Henniker AJ, Horejsi V, Sagawa K, Skubitz KM, Taskov H, Todd RF 3rd, van Agthoven A, Katz DR, Chain BM.

Int Immunol. 2000 Jul;12(7):1051-61.


Pure populations of transduced primary human cells can be produced using GFP expressing herpes virus vectors and flow cytometry.

Coffin RS, Thomas SK, Thomas NS, Lilley CE, Pizzey AR, Griffiths CH, Gibb BJ, Wagstaff MJ, Inges SJ, Binks MH, Chain BM, Thrasher AJ, Rutault K, Latchman DS.

Gene Ther. 1998 May;5(5):718-22.


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