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Items: 1 to 20 of 81


Novel function of ceramide for regulation of mitochondrial ATP release in astrocytes.

Kong JN, Zhu Z, Itokazu Y, Wang G, Dinkins MB, Zhong L, Lin HP, Elsherbini A, Leanhart S, Jiang X, Qin H, Zhi W, Spassieva SD, Bieberich E.

J Lipid Res. 2018 Mar;59(3):488-506. doi: 10.1194/jlr.M081877. Epub 2018 Jan 10.


Promotion of endocytosis efficiency through an ATP-independent mechanism at rat calyx of Held terminals.

Yue HY, Bieberich E, Xu J.

J Physiol. 2017 Aug 1;595(15):5265-5284. doi: 10.1113/JP274275. Epub 2017 Jul 5.


Ceramide and S1P Signaling in Embryonic Stem Cell Differentiation.

Wang G, Spassieva SD, Bieberich E.

Methods Mol Biol. 2018;1697:153-171. doi: 10.1007/7651_2017_43.


Characterization of Plasma Membrane Ceramides by Super-Resolution Microscopy.

Burgert A, Schlegel J, Bécam J, Doose S, Bieberich E, Schubert-Unkmeir A, Sauer M.

Angew Chem Int Ed Engl. 2017 May 22;56(22):6131-6135. doi: 10.1002/anie.201700570. Epub 2017 Apr 5.


A Comparative Study of Serum Exosome Isolation Using Differential Ultracentrifugation and Three Commercial Reagents.

Helwa I, Cai J, Drewry MD, Zimmerman A, Dinkins MB, Khaled ML, Seremwe M, Dismuke WM, Bieberich E, Stamer WD, Hamrick MW, Liu Y.

PLoS One. 2017 Jan 23;12(1):e0170628. doi: 10.1371/journal.pone.0170628. eCollection 2017.


Sphingolipid-Enriched Extracellular Vesicles and Alzheimer's Disease: A Decade of Research.

Dinkins MB, Wang G, Bieberich E.

J Alzheimers Dis. 2017;60(3):757-768. doi: 10.3233/JAD-160567.


Lysosphingolipids and sphingolipidoses: Psychosine in Krabbe's disease.

Spassieva S, Bieberich E.

J Neurosci Res. 2016 Nov;94(11):974-81. doi: 10.1002/jnr.23888. Review.


Neutral Sphingomyelinase-2 Deficiency Ameliorates Alzheimer's Disease Pathology and Improves Cognition in the 5XFAD Mouse.

Dinkins MB, Enasko J, Hernandez C, Wang G, Kong J, Helwa I, Liu Y, Terry AV Jr, Bieberich E.

J Neurosci. 2016 Aug 17;36(33):8653-67. doi: 10.1523/JNEUROSCI.1429-16.2016.


Incorporation and visualization of azido-functionalized N-oleoyl serinol in Jurkat cells, mouse brain astrocytes, 3T3 fibroblasts and human brain microvascular endothelial cells.

Walter T, Collenburg L, Japtok L, Kleuser B, Schneider-Schaulies S, Müller N, Becam J, Schubert-Unkmeir A, Kong JN, Bieberich E, Seibel J.

Chem Commun (Camb). 2016 Jun 30;52(55):8612-8614. doi: 10.1039/c6cc02879a.


Ectopic expression of ceramide synthase 2 in neurons suppresses neurodegeneration induced by ceramide synthase 1 deficiency.

Spassieva SD, Ji X, Liu Y, Gable K, Bielawski J, Dunn TM, Bieberich E, Zhao L.

Proc Natl Acad Sci U S A. 2016 May 24;113(21):5928-33. doi: 10.1073/pnas.1522071113. Epub 2016 May 9.


Regulation of Chlamydomonas flagella and ependymal cell motile cilia by ceramide-mediated translocation of GSK3.

Kong JN, Hardin K, Dinkins M, Wang G, He Q, Mujadzic T, Zhu G, Bielawski J, Spassieva S, Bieberich E.

Mol Biol Cell. 2015 Dec 1;26(24):4451-65. doi: 10.1091/mbc.E15-06-0371. Epub 2015 Oct 7.


Guggulsterone and bexarotene induce secretion of exosome-associated breast cancer resistance protein and reduce doxorubicin resistance in MDA-MB-231 cells.

Kong JN, He Q, Wang G, Dasgupta S, Dinkins MB, Zhu G, Kim A, Spassieva S, Bieberich E.

Int J Cancer. 2015 Oct 1;137(7):1610-20. doi: 10.1002/ijc.29542. Epub 2015 Apr 27.


Critical role of Spns2, a sphingosine-1-phosphate transporter, in lung cancer cell survival and migration.

Bradley E, Dasgupta S, Jiang X, Zhao X, Zhu G, He Q, Dinkins M, Bieberich E, Wang G.

PLoS One. 2014 Oct 20;9(10):e110119. doi: 10.1371/journal.pone.0110119. eCollection 2014.


Low dose Hsp90 inhibitor 17AAG protects neural progenitor cells from ischemia induced death.

Bradley E, Zhao X, Wang R, Brann D, Bieberich E, Wang G.

J Cell Commun Signal. 2014 Dec;8(4):353-62. doi: 10.1007/s12079-014-0247-5. Epub 2014 Oct 4.


Synthesis, Processing, and Function of N-glycans in N-glycoproteins.

Bieberich E.

Adv Neurobiol. 2014;9:47-70. doi: 10.1007/978-1-4939-1154-7_3.


The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1.

Janes K, Little JW, Li C, Bryant L, Chen C, Chen Z, Kamocki K, Doyle T, Snider A, Esposito E, Cuzzocrea S, Bieberich E, Obeid L, Petrache I, Nicol G, Neumann WL, Salvemini D.

J Biol Chem. 2014 Jul 25;289(30):21082-97.


Primary cilia in stem cells and neural progenitors are regulated by neutral sphingomyelinase 2 and ceramide.

He Q, Wang G, Wakade S, Dasgupta S, Dinkins M, Kong JN, Spassieva SD, Bieberich E.

Mol Biol Cell. 2014 Jun;25(11):1715-29. doi: 10.1091/mbc.E13-12-0730. Epub 2014 Apr 2.


Exosome reduction in vivo is associated with lower amyloid plaque load in the 5XFAD mouse model of Alzheimer's disease.

Dinkins MB, Dasgupta S, Wang G, Zhu G, Bieberich E.

Neurobiol Aging. 2014 Aug;35(8):1792-800. doi: 10.1016/j.neurobiolaging.2014.02.012. Epub 2014 Feb 15.


Ceramide targets xIAP and cIAP1 to sensitize metastatic colon and breast cancer cells to apoptosis induction to suppress tumor progression.

Paschall AV, Zimmerman MA, Torres CM, Yang D, Chen MR, Li X, Bieberich E, Bai A, Bielawski J, Bielawska A, Liu K.

BMC Cancer. 2014 Jan 15;14:24. doi: 10.1186/1471-2407-14-24.

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