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Items: 1 to 20 of 128


Repo-Man/PP1 regulates heterochromatin formation in interphase.

de Castro IJ, Budzak J, Di Giacinto ML, Ligammari L, Gokhan E, Spanos C, Moralli D, Richardson C, de Las Heras JI, Salatino S, Schirmer EC, Ullman KS, Bickmore WA, Green C, Rappsilber J, Lamble S, Goldberg MW, Vinciotti V, Vagnarelli P.

Nat Commun. 2017 Jan 16;8:14048. doi: 10.1038/ncomms14048.


A Hox-Embedded Long Noncoding RNA: Is It All Hot Air?

Selleri L, Bartolomei MS, Bickmore WA, He L, Stubbs L, Reik W, Barsh GS.

PLoS Genet. 2016 Dec 15;12(12):e1006485. doi: 10.1371/journal.pgen.1006485. No abstract available.


SBE6: a novel long-range enhancer involved in driving sonic hedgehog expression in neural progenitor cells.

Benabdallah NS, Gautier P, Hekimoglu-Balkan B, Lettice LA, Bhatia S, Bickmore WA.

Open Biol. 2016 Nov;6(11). pii: 160197.


Condensin II mutation causes T-cell lymphoma through tissue-specific genome instability.

Woodward J, Taylor GC, Soares DC, Boyle S, Sie D, Read D, Chathoth K, Vukovic M, Tarrats N, Jamieson D, Campbell KJ, Blyth K, Acosta JC, Ylstra B, Arends MJ, Kranc KR, Jackson AP, Bickmore WA, Wood AJ.

Genes Dev. 2016 Oct 1;30(19):2173-2186.


Polycomb enables primitive endoderm lineage priming in embryonic stem cells.

Illingworth RS, Hölzenspies JJ, Roske FV, Bickmore WA, Brickman JM.

Elife. 2016 Oct 10;5. pii: e14926. doi: 10.7554/eLife.14926.


Shh and ZRS enhancer colocalisation is specific to the zone of polarising activity.

Williamson I, Lettice LA, Hill RE, Bickmore WA.

Development. 2016 Aug 15;143(16):2994-3001. doi: 10.1242/dev.139188.


Histone H3 globular domain acetylation identifies a new class of enhancers.

Pradeepa MM, Grimes GR, Kumar Y, Olley G, Taylor GC, Schneider R, Bickmore WA.

Nat Genet. 2016 Jun;48(6):681-6. doi: 10.1038/ng.3550.


Polycomb-mediated chromatin compaction weathers the STORM.

Williamson I, Bickmore WA, Illingworth RS.

Genome Biol. 2016 Feb 25;17:35. doi: 10.1186/s13059-016-0899-y.


Enhancer Turnover Is Associated with a Divergent Transcriptional Response to Glucocorticoid in Mouse and Human Macrophages.

Jubb AW, Young RS, Hume DA, Bickmore WA.

J Immunol. 2016 Jan 15;196(2):813-22. doi: 10.4049/jimmunol.1502009.


The Hierarchy of Transcriptional Activation: From Enhancer to Promoter.

Vernimmen D, Bickmore WA.

Trends Genet. 2015 Dec;31(12):696-708. doi: 10.1016/j.tig.2015.10.004. Review.


Regulatory Domains and Their Mechanisms.

Benabdallah NS, Bickmore WA.

Cold Spring Harb Symp Quant Biol. 2015;80:45-51. doi: 10.1101/sqb.2015.80.027268. Review.


The E3 ubiquitin ligase activity of RING1B is not essential for early mouse development.

Illingworth RS, Moffat M, Mann AR, Read D, Hunter CJ, Pradeepa MM, Adams IR, Bickmore WA.

Genes Dev. 2015 Sep 15;29(18):1897-902. doi: 10.1101/gad.268151.115.


Estrogen-induced chromatin decondensation and nuclear re-organization linked to regional epigenetic regulation in breast cancer.

Rafique S, Thomas JS, Sproul D, Bickmore WA.

Genome Biol. 2015 Aug 3;16:145. doi: 10.1186/s13059-015-0719-9.


The frequent evolutionary birth and death of functional promoters in mouse and human.

Young RS, Hayashizaki Y, Andersson R, Sandelin A, Kawaji H, Itoh M, Lassmann T, Carninci P; FANTOM Consortium., Bickmore WA, Forrest AR, Taylor MS.

Genome Res. 2015 Oct;25(10):1546-57. doi: 10.1101/gr.190546.115.


An Overview of Genome Organization and How We Got There: from FISH to Hi-C.

Fraser J, Williamson I, Bickmore WA, Dostie J.

Microbiol Mol Biol Rev. 2015 Sep;79(3):347-72. doi: 10.1128/MMBR.00006-15. Review.


Chromatin at the nuclear periphery and the regulation of genome functions.

Lemaître C, Bickmore WA.

Histochem Cell Biol. 2015 Aug;144(2):111-22. doi: 10.1007/s00418-015-1346-y. Review.


A TAD Closer to Understanding Dosage Compensation.

Wood AJ, Bickmore WA.

Dev Cell. 2015 Jun 8;33(5):498-9. doi: 10.1016/j.devcel.2015.05.021.


Spatial genome organization: contrasting views from chromosome conformation capture and fluorescence in situ hybridization.

Williamson I, Berlivet S, Eskeland R, Boyle S, Illingworth RS, Paquette D, Dostie J, Bickmore WA.

Genes Dev. 2014 Dec 15;28(24):2778-91. doi: 10.1101/gad.251694.114.


Chromatin decondensation is sufficient to alter nuclear organization in embryonic stem cells.

Therizols P, Illingworth RS, Courilleau C, Boyle S, Wood AJ, Bickmore WA.

Science. 2014 Dec 5;346(6214):1238-42. doi: 10.1126/science.1259587.


Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins.

Pradeepa MM, Grimes GR, Taylor GC, Sutherland HG, Bickmore WA.

Nucleic Acids Res. 2014 Aug;42(14):9021-32. doi: 10.1093/nar/gku647.

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