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Items: 1 to 20 of 128


Misery loves company - shared features of neurodegenerative disorders.

Bezprozvanny I, Sorgato MC, Carafoli E.

Biochem Biophys Res Commun. 2017 Feb 19;483(4):979-980. doi: 10.1016/j.bbrc.2017.01.099. No abstract available.


Neurons from skin mimic brain holes.

Bezprozvanny I, Kiselev SL.

Oncotarget. 2017 Feb 7;8(6):8997-8998. doi: 10.18632/oncotarget.13709. No abstract available.


Store-Operated Calcium Channel Complex in Postsynaptic Spines: A New Therapeutic Target for Alzheimer's Disease Treatment.

Zhang H, Sun S, Wu L, Pchitskaya E, Zakharova O, Fon Tacer K, Bezprozvanny I.

J Neurosci. 2016 Nov 23;36(47):11837-11850.


The sigma-1 receptor mediates the beneficial effects of pridopidine in a mouse model of Huntington disease.

Ryskamp D, Wu J, Geva M, Kusko R, Grossman I, Hayden M, Bezprozvanny I.

Neurobiol Dis. 2017 Jan;97(Pt A):46-59. doi: 10.1016/j.nbd.2016.10.006. Epub 2016 Nov 3.


Dysregulation of neuronal calcium homeostasis in Alzheimer's disease - A therapeutic opportunity?

Popugaeva E, Pchitskaya E, Bezprozvanny I.

Biochem Biophys Res Commun. 2017 Feb 19;483(4):998-1004. doi: 10.1016/j.bbrc.2016.09.053. Epub 2016 Sep 15. Review.


The 2.2-Angstrom resolution crystal structure of the carboxy-terminal region of ataxin-3.

Zhemkov VA, Kulminskaya AA, Bezprozvanny IB, Kim M.

FEBS Open Bio. 2016 Feb 18;6(3):168-78. doi: 10.1002/2211-5463.12029. eCollection 2016 Mar.


In vivo analysis of cerebellar Purkinje cell activity in SCA2 transgenic mouse model.

Egorova PA, Zakharova OA, Vlasova OL, Bezprozvanny IB.

J Neurophysiol. 2016 Jun 1;115(6):2840-51. doi: 10.1152/jn.00913.2015. Epub 2016 Mar 16.


Enhanced Store-Operated Calcium Entry Leads to Striatal Synaptic Loss in a Huntington's Disease Mouse Model.

Wu J, Ryskamp DA, Liang X, Egorova P, Zakharova O, Hung G, Bezprozvanny I.

J Neurosci. 2016 Jan 6;36(1):125-41. doi: 10.1523/JNEUROSCI.1038-15.2016.


AF710B, a Novel M1/σ1 Agonist with Therapeutic Efficacy in Animal Models of Alzheimer’s Disease.

Fisher A, Bezprozvanny I, Wu L, Ryskamp DA, Bar-Ner N, Natan N, Brandeis R, Elkon H, Nahum V, Gershonov E, LaFerla FM, Medeiros R.

Neurodegener Dis. 2016;16(1-2):95-110.


Restoring calcium homeostasis to treat Alzheimer's disease: a future perspective.

Popugaeva E, Vlasova OL, Bezprozvanny I.

Neurodegener Dis Manag. 2015 Oct;5(5):395-8. doi: 10.2217/nmt.15.36. Epub 2015 Oct 19. Review.


Autism-Associated Chromatin Regulator Brg1/SmarcA4 Is Required for Synapse Development and Myocyte Enhancer Factor 2-Mediated Synapse Remodeling.

Zhang Z, Cao M, Chang CW, Wang C, Shi X, Zhan X, Birnbaum SG, Bezprozvanny I, Huber KM, Wu JI.

Mol Cell Biol. 2015 Oct 12;36(1):70-83. doi: 10.1128/MCB.00534-15. Print 2016 Jan 1.


Neuronal Store-Operated Calcium Entry and Mushroom Spine Loss in Amyloid Precursor Protein Knock-In Mouse Model of Alzheimer's Disease.

Zhang H, Wu L, Pchitskaya E, Zakharova O, Saito T, Saido T, Bezprozvanny I.

J Neurosci. 2015 Sep 30;35(39):13275-86. doi: 10.1523/JNEUROSCI.1034-15.2015.


STIM2 protects hippocampal mushroom spines from amyloid synaptotoxicity.

Popugaeva E, Pchitskaya E, Speshilova A, Alexandrov S, Zhang H, Vlasova O, Bezprozvanny I.

Mol Neurodegener. 2015 Aug 15;10:37. doi: 10.1186/s13024-015-0034-7.


Disturbed calcium signaling in spinocerebellar ataxias and Alzheimer's disease.

Egorova P, Popugaeva E, Bezprozvanny I.

Semin Cell Dev Biol. 2015 Apr;40:127-33. doi: 10.1016/j.semcdb.2015.03.010. Epub 2015 Apr 4. Review.


Calcium signaling, excitability, and synaptic plasticity defects in a mouse model of Alzheimer's disease.

Zhang H, Liu J, Sun S, Pchitskaya E, Popugaeva E, Bezprozvanny I.

J Alzheimers Dis. 2015;45(2):561-80. doi: 10.3233/JAD-142427.


An automated and quantitative method to evaluate progression of striatal pathology in Huntington's disease transgenic mice.

Liang X, Wu J, Egorova P, Bezprozvanny I.

J Huntingtons Dis. 2014;3(4):343-50. doi: 10.3233/JHD-140128.


Commentary on "Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice".

Popugaeva E, Bezprozvanny I.

Front Cell Neurosci. 2014 Oct 28;8:351. doi: 10.3389/fncel.2014.00351. eCollection 2014. No abstract available.


Simplified method to perform CLARITY imaging.

Poguzhelskaya E, Artamonov D, Bolshakova A, Vlasova O, Bezprozvanny I.

Mol Neurodegener. 2014 May 26;9:19. doi: 10.1186/1750-1326-9-19.


Reduced synaptic STIM2 expression and impaired store-operated calcium entry cause destabilization of mature spines in mutant presenilin mice.

Sun S, Zhang H, Liu J, Popugaeva E, Xu NJ, Feske S, White CL 3rd, Bezprozvanny I.

Neuron. 2014 Apr 2;82(1):79-93. doi: 10.1016/j.neuron.2014.02.019.


The role of ryanodine receptor type 3 in a mouse model of Alzheimer disease.

Liu J, Supnet C, Sun S, Zhang H, Good L, Popugaeva E, Bezprozvanny I.

Channels (Austin). 2014;8(3):230-42.

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