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Items: 1 to 20 of 24


Derivation and Evaluation of Putative Adverse Outcome Pathways for the Effects of Cyclooxygenase Inhibitors on Reproductive Processes in Female Fish.

Martinovic-Weigelt D, Mehinto AC, Ankley GT, Berninger JP, Collette TW, Davis JM, Denslow ND, Durhan EJ, Eid E, Ekman DR, Jensen KM, Kahl MD, LaLone CA, Teng Q, Villeneuve DL.

Toxicol Sci. 2017 Apr 1;156(2):344-361. doi: 10.1093/toxsci/kfw257.


An integrated approach for identifying priority contaminant in the Great Lakes Basin - Investigations in the Lower Green Bay/Fox River and Milwaukee Estuary areas of concern.

Li S, Villeneuve DL, Berninger JP, Blackwell BR, Cavallin JE, Hughes MN, Jensen KM, Jorgenson Z, Kahl MD, Schroeder AL, Stevens KE, Thomas LM, Weberg MA, Ankley GT.

Sci Total Environ. 2017 Feb 1;579:825-837. doi: 10.1016/j.scitotenv.2016.11.021. Epub 2016 Nov 18.


Linking field-based metabolomics and chemical analyses to prioritize contaminants of emerging concern in the Great Lakes basin.

Davis JM, Ekman DR, Teng Q, Ankley GT, Berninger JP, Cavallin JE, Jensen KM, Kahl MD, Schroeder AL, Villeneuve DL, Jorgenson ZG, Lee KE, Collette TW.

Environ Toxicol Chem. 2016 Oct;35(10):2493-2502. doi: 10.1002/etc.3409. Epub 2016 Jun 21.


In vivo and In vitro neurochemical-based assessments of wastewater effluents from the Maumee River area of concern.

Arini A, Cavallin JE, Berninger JP, Marfil-Vega R, Mills M, Villeneuve DL, Basu N.

Environ Pollut. 2016 Apr;211:9-19. doi: 10.1016/j.envpol.2015.12.028. Epub 2015 Dec 29.


Pathway-based approaches for assessment of real-time exposure to an estrogenic wastewater treatment plant effluent on fathead minnow reproduction.

Cavallin JE, Jensen KM, Kahl MD, Villeneuve DL, Lee KE, Schroeder AL, Mayasich J, Eid EP, Nelson KR, Milsk RY, Blackwell BR, Berninger JP, LaLone CA, Blanksma C, Jicha T, Elonen C, Johnson R, Ankley GT.

Environ Toxicol Chem. 2016 Mar;35(3):702-16. doi: 10.1002/etc.3228. Epub 2016 Feb 9.


Observed and modeled effects of pH on bioconcentration of diphenhydramine, a weakly basic pharmaceutical, in fathead minnows.

Nichols JW, Du B, Berninger JP, Connors KA, Chambliss CK, Erickson RJ, Hoffman AD, Brooks BW.

Environ Toxicol Chem. 2015 Jun;34(6):1425-35. doi: 10.1002/etc.2948. Epub 2015 Apr 28.


Prioritization of pharmaceuticals for potential environmental hazard through leveraging a large-scale mammalian pharmacological dataset.

Berninger JP, LaLone CA, Villeneuve DL, Ankley GT.

Environ Toxicol Chem. 2016 Apr;35(4):1007-20. doi: 10.1002/etc.2965. Epub 2015 Jun 22.


Leveraging existing data for prioritization of the ecological risks of human and veterinary pharmaceuticals to aquatic organisms.

LaLone CA, Berninger JP, Villeneuve DL, Ankley GT.

Philos Trans R Soc Lond B Biol Sci. 2014 Nov 19;369(1656). pii: 20140022. doi: 10.1098/rstb.2014.0022. Review.


Comparative pharmacology and toxicology of pharmaceuticals in the environment: diphenhydramine protection of diazinon toxicity in Danio rerio but not Daphnia magna.

Kristofco LA, Du B, Chambliss CK, Berninger JP, Brooks BW.

AAPS J. 2015 Jan;17(1):175-83. doi: 10.1208/s12248-014-9677-5. Epub 2014 Oct 18.


An inexpensive, temporally integrated system for monitoring occurrence and biological effects of aquatic contaminants in the field.

Kahl MD, Villeneuve DL, Stevens K, Schroeder A, Makynen EA, LaLone CA, Jensen KM, Hughes M, Holmen BA, Eid E, Durhan EJ, Cavallin JE, Berninger J, Ankley GT.

Environ Toxicol Chem. 2014 Jul;33(7):1584-95. doi: 10.1002/etc.2591. Epub 2014 May 20.


Using transcriptomic tools to evaluate biological effects across effluent gradients at a diverse set of study sites in Minnesota, USA.

Berninger JP, Martinović-Weigelt D, Garcia-Reyero N, Escalon L, Perkins EJ, Ankley GT, Villeneuve DL.

Environ Sci Technol. 2014 Feb 18;48(4):2404-12. doi: 10.1021/es4040254. Epub 2014 Jan 27.


Molecular target sequence similarity as a basis for species extrapolation to assess the ecological risk of chemicals with known modes of action.

Lalone CA, Villeneuve DL, Burgoon LD, Russom CL, Helgen HW, Berninger JP, Tietge JE, Severson MN, Cavallin JE, Ankley GT.

Aquat Toxicol. 2013 Nov 15;144-145:141-54. doi: 10.1016/j.aquatox.2013.09.004. Epub 2013 Sep 19.


Cross-species sensitivity to a novel androgen receptor agonist of potential environmental concern, spironolactone.

LaLone CA, Villeneuve DL, Cavallin JE, Kahl MD, Durhan EJ, Makynen EA, Jensen KM, Stevens KE, Severson MN, Blanksma CA, Flynn KM, Hartig PC, Woodard JS, Berninger JP, Norberg-King TJ, Johnson RD, Ankley GT.

Environ Toxicol Chem. 2013 Nov;32(11):2528-41. doi: 10.1002/etc.2330. Epub 2013 Sep 6.


Nutrient stoichiometry and concentrations influence silver toxicity in the aquatic macrophyte Lemna gibba.

Bian J, Berninger JP, Fulton BA, Brooks BW.

Sci Total Environ. 2013 Apr 1;449:229-36. doi: 10.1016/j.scitotenv.2012.12.098. Epub 2013 Feb 19.


Sickle cell disease incidence among newborns in New York State by maternal race/ethnicity and nativity.

Wang Y, Kennedy J, Caggana M, Zimmerman R, Thomas S, Berninger J, Harris K, Green NS, Oyeku S, Hulihan M, Grant AM, Grosse SD.

Genet Med. 2013 Mar;15(3):222-8. doi: 10.1038/gim.2012.128. Epub 2012 Sep 27.


Pharmaceuticals in the environment: lessons learned for reducing uncertainties in environmental risk assessment.

Brooks BW, Berninger JP, Kristofco LA, Ramirez AJ, Stanley JK, Valenti TW.

Prog Mol Biol Transl Sci. 2012;112:231-58. doi: 10.1016/B978-0-12-415813-9.00008-8. Review.


Pharmaceuticals and personal care products in the environment: what are the big questions?

Boxall AB, Rudd MA, Brooks BW, Caldwell DJ, Choi K, Hickmann S, Innes E, Ostapyk K, Staveley JP, Verslycke T, Ankley GT, Beazley KF, Belanger SE, Berninger JP, Carriquiriborde P, Coors A, Deleo PC, Dyer SD, Ericson JF, Gagné F, Giesy JP, Gouin T, Hallstrom L, Karlsson MV, Larsson DG, Lazorchak JM, Mastrocco F, McLaughlin A, McMaster ME, Meyerhoff RD, Moore R, Parrott JL, Snape JR, Murray-Smith R, Servos MR, Sibley PK, Straub JO, Szabo ND, Topp E, Tetreault GR, Trudeau VL, Van Der Kraak G.

Environ Health Perspect. 2012 Sep;120(9):1221-9. doi: 10.1289/ehp.1104477. Epub 2012 May 30. Review.


Community annotation and bioinformatics workforce development in concert--Little Skate Genome Annotation Workshops and Jamborees.

Wang Q, Arighi CN, King BL, Polson SW, Vincent J, Chen C, Huang H, Kingham BF, Page ST, Rendino MF, Thomas WK, Udwary DW, Wu CH; North East Bioinformatics Collaborative Curation Team.

Database (Oxford). 2012 Mar 20;2012:bar064. doi: 10.1093/database/bar064. Print 2012.


Human therapeutic plasma levels of the selective serotonin reuptake inhibitor (SSRI) sertraline decrease serotonin reuptake transporter binding and shelter-seeking behavior in adult male fathead minnows.

Valenti TW, Gould GG, Berninger JP, Connors KA, Keele NB, Prosser KN, Brooks BW.

Environ Sci Technol. 2012 Feb 21;46(4):2427-35. doi: 10.1021/es204164b. Epub 2012 Feb 7.


Effects of the antihistamine diphenhydramine on selected aquatic organisms.

Berninger JP, Du B, Connors KA, Eytcheson SA, Kolkmeier MA, Prosser KN, Valenti TW Jr, Chambliss CK, Brooks BW.

Environ Toxicol Chem. 2011 Sep;30(9):2065-72. doi: 10.1002/etc.590. Epub 2011 Jul 13.


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