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Items: 1 to 20 of 237


Functional and morphological differences of the lung upon acute and chronic ozone exposure in mice.

Michaudel C, Fauconnier L, Julé Y, Ryffel B.

Sci Rep. 2018 Jul 13;8(1):10611. doi: 10.1038/s41598-018-28261-9.


The IL-33 Receptor ST2 Regulates Pulmonary Inflammation and Fibrosis to Bleomycin.

Fanny M, Nascimento M, Baron L, Schricke C, Maillet I, Akbal M, Riteau N, Le Bert M, Quesniaux V, Ryffel B, Gombault A, Même S, Même W, Couillin I.

Front Immunol. 2018 Jun 25;9:1476. doi: 10.3389/fimmu.2018.01476. eCollection 2018.


Transmembrane TNF and Partially TNFR1 Regulate TNFR2 Expression and Control Inflammation in Mycobacterial-Induced Pleurisy.

Uysal H, Chavez-Galan L, Vesin D, Blaser G, Benkhoucha M, Ryffel B, Quesniaux VFJ, Garcia I.

Int J Mol Sci. 2018 Jul 4;19(7). pii: E1959. doi: 10.3390/ijms19071959.


G-quadruplex DNA targeting alters class switch recombination in B cells and attenuates allergic inflammation.

Dalloul Z, Chenuet P, Dalloul I, Boyer F, Aldigier JC, Laffleur B, El Makhour Y, Ryffel B, Quesniaux VF, Togbé D, Mergny JL, Cook-Moreau J, Cogné M.

J Allergy Clin Immunol. 2018 Jun 20. pii: S0091-6749(18)30895-9. doi: 10.1016/j.jaci.2018.06.011. [Epub ahead of print]


Succinate receptor deficiency attenuates arthritis by reducing dendritic cell traffic and expansion of Th17 cells in the lymph nodes.

Saraiva AL, Veras FP, Peres RS, Talbot J, de Lima KA, Luiz JP, Carballido JM, Cunha TM, Cunha FQ, Ryffel B, Alves-Filho JC.

FASEB J. 2018 Jun 12:fj201800285. doi: 10.1096/fj.201800285. [Epub ahead of print]


PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer.

Dosset M, Vargas TR, Lagrange A, Boidot R, Végran F, Roussey A, Chalmin F, Dondaine L, Paul C, Lauret Marie-Joseph E, Martin F, Ryffel B, Borg C, Adotévi O, Ghiringhelli F, Apetoh L.

Oncoimmunology. 2018 Mar 15;7(6):e1433981. doi: 10.1080/2162402X.2018.1433981. eCollection 2018.


GM-CSF targeted immunomodulation affects host response to M. tuberculosis infection.

Benmerzoug S, Marinho FV, Rose S, Mackowiak C, Gosset D, Sedda D, Poisson E, Uyttenhove C, Van Snick J, Jacobs M, Garcia I, Ryffel B, Quesniaux VFJ.

Sci Rep. 2018 Jun 5;8(1):8652. doi: 10.1038/s41598-018-26984-3.


Interleukin-1α Mediates Ozone-Induced Myeloid Differentiation Factor-88-Dependent Epithelial Tissue Injury and Inflammation.

Michaudel C, Maillet I, Fauconnier L, Quesniaux V, Chung KF, Wiegman C, Peter D, Ryffel B.

Front Immunol. 2018 May 7;9:916. doi: 10.3389/fimmu.2018.00916. eCollection 2018.


The cGAS/STING Pathway Is Important for Dendritic Cell Activation but Is Not Essential to Induce Protective Immunity against Mycobacterium tuberculosis Infection.

Marinho FV, Benmerzoug S, Rose S, Campos PC, Marques JT, Báfica A, Barber G, Ryffel B, Oliveira SC, Quesniaux VFJ.

J Innate Immun. 2018;10(3):239-252. doi: 10.1159/000488952. Epub 2018 May 23.


Induction of NLRP3 Inflammasome Activation by Heme in Human Endothelial Cells.

Erdei J, Tóth A, Balogh E, Nyakundi BB, Bányai E, Ryffel B, Paragh G, Cordero MD, Jeney V.

Oxid Med Cell Longev. 2018 Mar 20;2018:4310816. doi: 10.1155/2018/4310816. eCollection 2018.


Interleukin-23 promotes intestinal T helper type17 immunity and ameliorates obesity-associated metabolic syndrome in a murine high-fat diet model.

Martins LMS, Perez MM, Pereira CA, Costa FRC, Dias MS, Tostes RC, Ramos SG, de Zoete MR, Ryffel B, Silva JS, Carlos D.

Immunology. 2018 May 2. doi: 10.1111/imm.12946. [Epub ahead of print]


MyD88 as a therapeutic target for inflammatory lung diseases.

Di Padova F, Quesniaux VFJ, Ryffel B.

Expert Opin Ther Targets. 2018 May;22(5):401-408. doi: 10.1080/14728222.2018.1464139. Epub 2018 Apr 20.


Gain of function mutation and inflammasome driven diseases in human and mouse models.

Cordero MD, Alcocer-Gómez E, Ryffel B.

J Autoimmun. 2018 Jul;91:13-22. doi: 10.1016/j.jaut.2018.03.002. Epub 2018 Mar 30. Review.


Humoral Responses Elicited by Adenovirus Displaying Epitopes Are Induced Independently of the Infection Process and Shaped by the Toll-Like Receptor/MyD88 Pathway.

Anchim A, Raddi N, Zig L, Perrieau P, Le Goffic R, Ryffel B, Benihoud K.

Front Immunol. 2018 Feb 5;9:124. doi: 10.3389/fimmu.2018.00124. eCollection 2018.


Ozone exposure induces respiratory barrier biphasic injury and inflammation controlled by IL-33.

Michaudel C, Mackowiak C, Maillet I, Fauconnier L, Akdis CA, Sokolowska M, Dreher A, Tan HT, Quesniaux VF, Ryffel B, Togbe D.

J Allergy Clin Immunol. 2018 Jan 10. pii: S0091-6749(18)30028-9. doi: 10.1016/j.jaci.2017.11.044. [Epub ahead of print]


Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway.

Holze C, Michaudel C, Mackowiak C, Haas DA, Benda C, Hubel P, Pennemann FL, Schnepf D, Wettmarshausen J, Braun M, Leung DW, Amarasinghe GK, Perocchi F, Staeheli P, Ryffel B, Pichlmair A.

Nat Immunol. 2018 Feb;19(2):130-140. doi: 10.1038/s41590-017-0013-y. Epub 2017 Dec 18.


NLRP3-inflammasome inhibition prevents high fat and high sugar diets-induced heart damage through autophagy induction.

Pavillard LE, Cañadas-Lozano D, Alcocer-Gómez E, Marín-Aguilar F, Pereira S, Robertson AAB, Muntané J, Ryffel B, Cooper MA, Quiles JL, Bullón P, Ruiz-Cabello J, Cordero MD.

Oncotarget. 2017 Sep 8;8(59):99740-99756. doi: 10.18632/oncotarget.20763. eCollection 2017 Nov 21.


Loss of vascular expression of nucleoside triphosphate diphosphohydrolase-1/CD39 in hypertension.

Roy C, Tabiasco J, Caillon A, Delneste Y, Merot J, Favre J, Guihot AL, Martin L, Nascimento DC, Ryffel B, Robson SC, Sévigny J, Henrion D, Kauffenstein G.

Purinergic Signal. 2018 Mar;14(1):73-82. doi: 10.1007/s11302-017-9597-9. Epub 2017 Dec 13.


Tumor Necrosis Factor-Alpha Targeting Can Protect against Arthritis with Low Sensitization to Infection.

Belmellat N, Semerano L, Segueni N, Damotte D, Decker P, Ryffel B, Quesniaux V, Boissier MC, Assier E.

Front Immunol. 2017 Nov 14;8:1533. doi: 10.3389/fimmu.2017.01533. eCollection 2017.


AMP-Activated Protein Kinase Regulation of the NLRP3 Inflammasome during Aging.

Cordero MD, Williams MR, Ryffel B.

Trends Endocrinol Metab. 2018 Jan;29(1):8-17. doi: 10.1016/j.tem.2017.10.009. Epub 2017 Nov 14. Review.


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