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Items: 1 to 20 of 127

1.

Replication Protein A Prohibits Diffusion of the PCNA Sliding Clamp along Single-Stranded DNA.

Hedglin M, Benkovic SJ.

Biochemistry. 2017 Apr 4;56(13):1824-1835. doi: 10.1021/acs.biochem.6b01213. Epub 2017 Feb 28.

2.

Characterization of human translesion DNA synthesis across a UV-induced DNA lesion.

Hedglin M, Pandey B, Benkovic SJ.

Elife. 2016 Oct 22;5. pii: e19788. doi: 10.7554/eLife.19788.

3.

Stability of the human polymerase δ holoenzyme and its implications in lagging strand DNA synthesis.

Hedglin M, Pandey B, Benkovic SJ.

Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):E1777-86. doi: 10.1073/pnas.1523653113. Epub 2016 Mar 14.

4.

Spatial colocalization and functional link of purinosomes with mitochondria.

French JB, Jones SA, Deng H, Pedley AM, Kim D, Chan CY, Hu H, Pugh RJ, Zhao H, Zhang Y, Huang TJ, Fang Y, Zhuang X, Benkovic SJ.

Science. 2016 Feb 12;351(6274):733-7. doi: 10.1126/science.aac6054.

5.

The use of modified and non-natural nucleotides provide unique insights into pro-mutagenic replication catalyzed by polymerase eta.

Choi JS, Dasari A, Hu P, Benkovic SJ, Berdis AJ.

Nucleic Acids Res. 2016 Feb 18;44(3):1022-35. doi: 10.1093/nar/gkv1509. Epub 2015 Dec 29.

6.

Protein Conformational Changes Are Detected and Resolved Site Specifically by Second-Harmonic Generation.

Moree B, Connell K, Mortensen RB, Liu CT, Benkovic SJ, Salafsky J.

Biophys J. 2015 Aug 18;109(4):806-15. doi: 10.1016/j.bpj.2015.07.016.

7.

Coordinated DNA Replication by the Bacteriophage T4 Replisome.

Noble E, Spiering MM, Benkovic SJ.

Viruses. 2015 Jun 19;7(6):3186-200. doi: 10.3390/v7062766. Review.

8.

Purinosome formation as a function of the cell cycle.

Chan CY, Zhao H, Pugh RJ, Pedley AM, French J, Jones SA, Zhuang X, Jinnah H, Huang TJ, Benkovic SJ.

Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1368-73. doi: 10.1073/pnas.1423009112. Epub 2015 Jan 20.

9.

Quantitative analysis of purine nucleotides indicates that purinosomes increase de novo purine biosynthesis.

Zhao H, Chiaro CR, Zhang L, Smith PB, Chan CY, Pedley AM, Pugh RJ, French JB, Patterson AD, Benkovic SJ.

J Biol Chem. 2015 Mar 13;290(11):6705-13. doi: 10.1074/jbc.M114.628701. Epub 2015 Jan 20.

10.

Controlling cell-cell interactions using surface acoustic waves.

Guo F, Li P, French JB, Mao Z, Zhao H, Li S, Nama N, Fick JR, Benkovic SJ, Huang TJ.

Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):43-8. doi: 10.1073/pnas.1422068112. Epub 2014 Dec 22.

11.

Escherichia coli dihydrofolate reductase catalyzed proton and hydride transfers: temporal order and the roles of Asp27 and Tyr100.

Liu CT, Francis K, Layfield JP, Huang X, Hammes-Schiffer S, Kohen A, Benkovic SJ.

Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18231-6. doi: 10.1073/pnas.1415940111. Epub 2014 Dec 1.

12.

Acoustofluidic chemical waveform generator and switch.

Ahmed D, Muddana HS, Lu M, French JB, Ozcelik A, Fang Y, Butler PJ, Benkovic SJ, Manz A, Huang TJ.

Anal Chem. 2014 Dec 2;86(23):11803-10. doi: 10.1021/ac5033676. Epub 2014 Nov 18.

13.

Tryptophan-based fluorophores for studying protein conformational changes.

Talukder P, Chen S, Liu CT, Baldwin EA, Benkovic SJ, Hecht SM.

Bioorg Med Chem. 2014 Nov 1;22(21):5924-34. doi: 10.1016/j.bmc.2014.09.015. Epub 2014 Sep 16.

14.

Probing the electrostatics of active site microenvironments along the catalytic cycle for Escherichia coli dihydrofolate reductase.

Liu CT, Layfield JP, Stewart RJ 3rd, French JB, Hanoian P, Asbury JB, Hammes-Schiffer S, Benkovic SJ.

J Am Chem Soc. 2014 Jul 23;136(29):10349-60. doi: 10.1021/ja5038947. Epub 2014 Jul 11.

15.

Dark-field illumination on zero-mode waveguide/microfluidic hybrid chip reveals T4 replisomal protein interactions.

Zhao Y, Chen D, Yue H, Spiering MM, Zhao C, Benkovic SJ, Huang TJ.

Nano Lett. 2014;14(4):1952-60. doi: 10.1021/nl404802f. Epub 2014 Mar 24.

16.

Fluorescent biphenyl derivatives of phenylalanine suitable for protein modification.

Chen S, Fahmi NE, Bhattacharya C, Wang L, Jin Y, Benkovic SJ, Hecht SM.

Biochemistry. 2013 Nov 26;52(47):8580-9. doi: 10.1021/bi401275v. Epub 2013 Nov 11.

17.

RecG and UvsW catalyse robust DNA rewinding critical for stalled DNA replication fork rescue.

Manosas M, Perumal SK, Bianco PR, Ritort F, Benkovic SJ, Croquette V.

Nat Commun. 2013;4:2368. doi: 10.1038/ncomms3368. Erratum in: Nat Commun. 2014;5:4210. Bianco, Piero [corrected to Bianco, Piero R].

18.

Detection of dihydrofolate reductase conformational change by FRET using two fluorescent amino acids.

Chen S, Fahmi NE, Wang L, Bhattacharya C, Benkovic SJ, Hecht SM.

J Am Chem Soc. 2013 Sep 4;135(35):12924-7. doi: 10.1021/ja403007r. Epub 2013 Aug 22.

19.

Temporally overlapped but uncoupled motions in dihydrofolate reductase catalysis.

Liu CT, Wang L, Goodey NM, Hanoian P, Benkovic SJ.

Biochemistry. 2013 Aug 13;52(32):5332-4. doi: 10.1021/bi400858m. Epub 2013 Jul 29.

20.

Probing cell-cell communication with microfluidic devices.

Guo F, French JB, Li P, Zhao H, Chan CY, Fick JR, Benkovic SJ, Huang TJ.

Lab Chip. 2013 Aug 21;13(16):3152-62. doi: 10.1039/c3lc90067c. Epub 2013 Jul 10. Review.

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