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Items: 1 to 20 of 118

1.

Antipsychotics differentially regulate insulin, energy sensing, and inflammation pathways in hypothalamic rat neurons.

Kowalchuk C, Kanagasundaram P, Belsham DD, Hahn MK.

Psychoneuroendocrinology. 2019 Jun;104:42-48. doi: 10.1016/j.psyneuen.2019.01.029. Epub 2019 Feb 1.

PMID:
30802709
2.
3.

Tumour necrosis factor α induces neuroinflammation and insulin resistance in immortalised hypothalamic neurones through independent pathways.

Clemenzi MN, Wellhauser L, Aljghami ME, Belsham DD.

J Neuroendocrinol. 2019 Jan;31(1):e12678. doi: 10.1111/jne.12678. Epub 2019 Jan 20.

PMID:
30582235
4.
5.

Bisphenol A Alters Bmal1, Per2, and Rev-Erba mRNA and Requires Bmal1 to Increase Neuropeptide Y Expression in Hypothalamic Neurons.

Loganathan N, Salehi A, Chalmers JA, Belsham DD.

Endocrinology. 2019 Jan 1;160(1):181-192. doi: 10.1210/en.2018-00881.

PMID:
30500912
6.

Palmitate Induces an Anti-Inflammatory Response in Immortalized Microglial BV-2 and IMG Cell Lines that Decreases TNFα Levels in mHypoE-46 Hypothalamic Neurons in Co-Culture.

Kim SM, McIlwraith EK, Chalmers JA, Belsham DD.

Neuroendocrinology. 2018;107(4):387-399. doi: 10.1159/000494759. Epub 2018 Oct 23.

PMID:
30352432
7.

Bisphenol A induces Pomc gene expression through neuroinflammatory and PPARγ nuclear receptor-mediated mechanisms in POMC-expressing hypothalamic neuronal models.

Salehi A, Loganathan N, Belsham DD.

Mol Cell Endocrinol. 2019 Jan 5;479:12-19. doi: 10.1016/j.mce.2018.08.009. Epub 2018 Aug 24.

PMID:
30149043
8.

3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid (CMPF) prevents high fat diet-induced insulin resistance via maintenance of hepatic lipid homeostasis.

Mohan H, Brandt SL, Kim JH, Wong F, Lai M, Prentice KJ, Al Rijjal D, Magomedova L, Batchuluun B, Burdett E, Bhattacharjee A, Cummins CL, Belsham DD, Cox B, Liu Y, Wheeler MB.

Diabetes Obes Metab. 2019 Jan;21(1):61-72. doi: 10.1111/dom.13483. Epub 2018 Sep 6.

PMID:
30062833
9.

Phoenixin: uncovering its receptor, signaling and functions.

Mcilwraith EK, Belsham DD.

Acta Pharmacol Sin. 2018 May;39(5):774-778. doi: 10.1038/aps.2018.13. Epub 2018 Apr 19. Review.

10.

Role of the saturated fatty acid palmitate in the interconnected hypothalamic control of energy homeostasis and biological rhythms.

Tse EK, Salehi A, Clemenzi MN, Belsham DD.

Am J Physiol Endocrinol Metab. 2018 Aug 1;315(2):E133-E140. doi: 10.1152/ajpendo.00433.2017. Epub 2018 Apr 6.

PMID:
29631363
11.

Palmitate induces neuroinflammation, ER stress, and Pomc mRNA expression in hypothalamic mHypoA-POMC/GFP neurons through novel mechanisms that are prevented by oleate.

Tse EK, Belsham DD.

Mol Cell Endocrinol. 2018 Sep 5;472:40-49. doi: 10.1016/j.mce.2017.11.017. Epub 2017 Nov 24.

PMID:
29180108
12.

Beneficial Effects of Metformin and/or Salicylate on Palmitate- or TNFα-Induced Neuroinflammatory Marker and Neuropeptide Gene Regulation in Immortalized NPY/AgRP Neurons.

Ye W, Ramos EH, Wong BC, Belsham DD.

PLoS One. 2016 Nov 28;11(11):e0166973. doi: 10.1371/journal.pone.0166973. eCollection 2016.

13.

Signaling in the hypothalamus: New concepts.

Belsham DD.

Mol Cell Endocrinol. 2016 Dec 15;438:1-2. doi: 10.1016/j.mce.2016.11.001. No abstract available.

PMID:
27863560
14.

High fat induces acute and chronic inflammation in the hypothalamus: effect of high-fat diet, palmitate and TNF-α on appetite-regulating NPY neurons.

Dalvi PS, Chalmers JA, Luo V, Han DY, Wellhauser L, Liu Y, Tran DQ, Castel J, Luquet S, Wheeler MB, Belsham DD.

Int J Obes (Lond). 2017 Jan;41(1):149-158. doi: 10.1038/ijo.2016.183. Epub 2016 Oct 24.

PMID:
27773938
15.

Nutrient-sensing mechanisms in hypothalamic cell models: neuropeptide regulation and neuroinflammation in male- and female-derived cell lines.

Loganathan N, Belsham DD.

Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R217-21. doi: 10.1152/ajpregu.00168.2016. Epub 2016 Jun 15. Review.

16.

Phoenixin Activates Immortalized GnRH and Kisspeptin Neurons Through the Novel Receptor GPR173.

Treen AK, Luo V, Belsham DD.

Mol Endocrinol. 2016 Aug;30(8):872-88. doi: 10.1210/me.2016-1039. Epub 2016 Jun 6.

17.

Diet-induced cellular neuroinflammation in the hypothalamus: Mechanistic insights from investigation of neurons and microglia.

Tran DQ, Tse EK, Kim MH, Belsham DD.

Mol Cell Endocrinol. 2016 Dec 15;438:18-26. doi: 10.1016/j.mce.2016.05.015. Epub 2016 May 18. Review.

PMID:
27208620
18.

Nitric Oxide Exerts Basal and Insulin-Dependent Anorexigenic Actions in POMC Hypothalamic Neurons.

Wellhauser L, Chalmers JA, Belsham DD.

Mol Endocrinol. 2016 Apr;30(4):402-16. doi: 10.1210/me.2015-1275. Epub 2016 Mar 1.

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