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Items: 1 to 20 of 56

1.

Optimization of Potent and Selective Tricyclic Indole Diazepinone Myeloid Cell Leukemia-1 Inhibitors Using Structure-Based Design.

Shaw S, Bian Z, Zhao B, Tarr JC, Veerasamy N, Jeon KO, Belmar J, Arnold AL, Fogarty SA, Perry E, Sensintaffar JL, Camper DV, Rossanese OW, Lee T, Olejniczak ET, Fesik SW.

J Med Chem. 2018 Mar 22;61(6):2410-2421. doi: 10.1021/acs.jmedchem.7b01155. Epub 2018 Mar 9.

PMID:
29323899
2.

[Antiretroviral treatment adherence for HIV/AIDS in women: a sociocultural perspective].

Belmar J, Stuardo V.

Rev Chilena Infectol. 2017 Aug;34(4):352-358. doi: 10.4067/s0716-10182017000400352. Spanish.

3.

A typology of female sex work in the Metropolitan Region of Santiago, Chile.

Belmar J, Stuardo V, Folch C, Carvajal B, Clunes MJ, Montoliu A, Casabona J.

Cult Health Sex. 2018 Apr;20(4):428-441. doi: 10.1080/13691058.2017.1355478. Epub 2017 Aug 11.

PMID:
28799462
4.

Structure of a Myeloid cell leukemia-1 (Mcl-1) inhibitor bound to drug site 3 of Human Serum Albumin.

Zhao B, Sensintaffar J, Bian Z, Belmar J, Lee T, Olejniczak ET, Fesik SW.

Bioorg Med Chem. 2017 Jun 15;25(12):3087-3092. doi: 10.1016/j.bmc.2017.03.060. Epub 2017 Mar 29.

PMID:
28428041
5.

[Survey adaptation for bio-behavioural surveillance of HIV in Chilean female sex workers].

Carvajal B, Stuardo V, Manríquez JM, Belmar J, Folch C.

Gac Sanit. 2017 Nov - Dec;31(6):478-484. doi: 10.1016/j.gaceta.2016.10.010. Epub 2017 Apr 12. Spanish.

6.

Discovery and biological characterization of potent myeloid cell leukemia-1 inhibitors.

Lee T, Bian Z, Zhao B, Hogdal LJ, Sensintaffar JL, Goodwin CM, Belmar J, Shaw S, Tarr JC, Veerasamy N, Matulis SM, Koss B, Fischer MA, Arnold AL, Camper DV, Browning CF, Rossanese OW, Budhraja A, Opferman J, Boise LH, Savona MR, Letai A, Olejniczak ET, Fesik SW.

FEBS Lett. 2017 Jan;591(1):240-251. doi: 10.1002/1873-3468.12497. Epub 2016 Dec 19.

7.

Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods.

Pelz NF, Bian Z, Zhao B, Shaw S, Tarr JC, Belmar J, Gregg C, Camper DV, Goodwin CM, Arnold AL, Sensintaffar JL, Friberg A, Rossanese OW, Lee T, Olejniczak ET, Fesik SW.

J Med Chem. 2016 Mar 10;59(5):2054-66. doi: 10.1021/acs.jmedchem.5b01660. Epub 2016 Feb 24.

8.

Discovery of tricyclic indoles that potently inhibit Mcl-1 using fragment-based methods and structure-based design.

Burke JP, Bian Z, Shaw S, Zhao B, Goodwin CM, Belmar J, Browning CF, Vigil D, Friberg A, Camper DV, Rossanese OW, Lee T, Olejniczak ET, Fesik SW.

J Med Chem. 2015 May 14;58(9):3794-805. doi: 10.1021/jm501984f. Epub 2015 Apr 17.

9.

Small molecule Mcl-1 inhibitors for the treatment of cancer.

Belmar J, Fesik SW.

Pharmacol Ther. 2015 Jan;145:76-84. doi: 10.1016/j.pharmthera.2014.08.003. Epub 2014 Aug 27. Review.

10.

Acetylsalicylic acid (aspirin) and salicylic acid interaction with the human erythrocyte membrane bilayer induce in vitro changes in the morphology of erythrocytes.

Suwalsky M, Belmar J, Villena F, Gallardo MJ, Jemiola-Rzeminska M, Strzalka K.

Arch Biochem Biophys. 2013 Nov 1;539(1):9-19. doi: 10.1016/j.abb.2013.09.006. Epub 2013 Sep 18.

PMID:
24055635
11.

Total synthesis of (±)-communesin F via a cycloaddition with indol-2-one.

Belmar J, Funk RL.

J Am Chem Soc. 2012 Oct 17;134(41):16941-3. doi: 10.1021/ja307277w. Epub 2012 Sep 28.

PMID:
22978807
12.

Total synthesis of (±)-isophellibiline.

Funk RL, Belmar J.

Tetrahedron Lett. 2012 Jan 11;53(2):176-178.

13.

[Listeria monocytogenes infection in pregnancy: experience of Pontificia Universidad Católica de Chile University Hospital].

Larraín de la C D, Abarzúa C F, Jourdan H Fd, Merino O P, Belmar J C, García C P.

Rev Chilena Infectol. 2008 Oct;25(5):336-41. doi: /S0716-10182008000500003. Epub 2008 Oct 1. Review. Spanish.

14.

[Diagnosis of congenital syphilis at delivery: maternal serum or cord blood?].

Abarzúa C F, Belmar J C, Rioseco R A, Parada B J, Quiroga G T, García C P.

Rev Chilena Infectol. 2008 Jun;25(3):155-61. doi: /S0716-10182008000300002. Epub 2008 Jun 24. Spanish.

15.

New anionic cobalt complexes using highly hindered bis-amides with varying donor abilities as ligands.

Jiménez CA, Belmar JB, Alderete J, Delgado FS, López-Rodríguez M, Peña O, Julve M, Ruiz-Perez C.

Dalton Trans. 2007 Jun 7;(21):2135-44. Epub 2007 Apr 23.

PMID:
17514334
16.

A unique tautomer of 1-n-hexyl-3-phenyl-1H-pyrazol-5-ol.

Belmar J, Jiménez C, Ruiz-Pérez C, Delgado FS, Baggio R.

Acta Crystallogr C. 2006 Oct;62(Pt 10):o599-601. Epub 2006 Sep 12.

PMID:
17008747
17.

An oximino tautomer of 1-n-decyl-4-hydroxyimino-3-methyl-1H-pyrazol-5(4H)-one.

Belmar J, Jiménez C, Ortiz L, Garland MT, Baggio R.

Acta Crystallogr C. 2006 Feb;62(Pt 2):o76-8. Epub 2006 Jan 14.

PMID:
16456291
18.

Bis{1-n-hexyl-3-methyl-4-[1-(phenylimino)propyl]-1H-pyrazol-5-olato}copper(II): a new copper(II) complex with a chelating alkylpyrazolone-based enamine.

Pérez FR, Belmar J, Jiménez C, Moreno Y, Hermosilla P, Baggio R.

Acta Crystallogr C. 2005 Jun;61(Pt 6):m318-20. Epub 2005 May 31.

PMID:
15930678
19.

Two enamines derived from 1-n-alkyl-3-methylpyrazol-5-ones.

Belmar J, Pérez FR, Moreno Y, Baggio R.

Acta Crystallogr C. 2004 Sep;60(Pt 9):o705-8. Epub 2004 Aug 31.

PMID:
15345863
20.

Effects of mild protein prenatal malnutrition and subsequent postnatal nutritional rehabilitation on noradrenaline release and neuronal density in the rat occipital cortex.

Soto-Moyano R, Fernandez V, Sanhueza M, Belmar J, Kusch C, Perez H, Ruiz S, Hernandez A.

Brain Res Dev Brain Res. 1999 Aug 5;116(1):51-8.

PMID:
10446346

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