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Items: 1 to 20 of 74

1.

Exploring the molecular basis of age-related disease comorbidities using a multi-omics graphical model.

Zierer J, Pallister T, Tsai PC, Krumsiek J, Bell JT, Lauc G, Spector TD, Menni C, Kastenmüller G.

Sci Rep. 2016 Nov 25;6:37646. doi: 10.1038/srep37646.

2.

ABO antigen and secretor statuses are not associated with gut microbiota composition in 1,500 twins.

Davenport ER, Goodrich JK, Bell JT, Spector TD, Ley RE, Clark AG.

BMC Genomics. 2016 Nov 21;17(1):941.

3.

A DNA methylation biomarker of alcohol consumption.

Liu C, Marioni RE, Hedman ÅK, Pfeiffer L, Tsai PC, Reynolds LM, Just AC, Duan Q, Boer CG, Tanaka T, Elks CE, Aslibekyan S, Brody JA, Kühnel B, Herder C, Almli LM, Zhi D, Wang Y, Huan T, Yao C, Mendelson MM, Joehanes R, Liang L, Love SA, Guan W, Shah S, McRae AF, Kretschmer A, Prokisch H, Strauch K, Peters A, Visscher PM, Wray NR, Guo X, Wiggins KL, Smith AK, Binder EB, Ressler KJ, Irvin MR, Absher DM, Hernandez D, Ferrucci L, Bandinelli S, Lohman K, Ding J, Trevisi L, Gustafsson S, Sandling JH, Stolk L, Uitterlinden AG, Yet I, Castillo-Fernandez JE, Spector TD, Schwartz JD, Vokonas P, Lind L, Li Y, Fornage M, Arnett DK, Wareham NJ, Sotoodehnia N, Ong KK, van Meurs JB, Conneely KN, Baccarelli AA, Deary IJ, Bell JT, North KE, Liu Y, Waldenberger M, London SJ, Ingelsson E, Levy D.

Mol Psychiatry. 2016 Nov 15. doi: 10.1038/mp.2016.192. [Epub ahead of print]

PMID:
27843151
4.

Epigenetic Signatures at AQP3 and SOCS3 Engage in Low-Grade Inflammation across Different Tissues.

Marzi C, Holdt LM, Fiorito G, Tsai PC, Kretschmer A, Wahl S, Guarrera S, Teupser D, Spector TD, Iacoviello L, Sacerdote C, Strauch K, Lee S, Thasler WE, Peters A, Thorand B, Wolf P, Prokisch H, Tumino R, Gieger C, Krogh V, Panico S, Bell JT, Matullo G, Waldenberger M, Grallert H, Koenig W.

PLoS One. 2016 Nov 8;11(11):e0166015. doi: 10.1371/journal.pone.0166015.

5.

Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome.

Xie H, Guo R, Zhong H, Feng Q, Lan Z, Qin B, Ward KJ, Jackson MA, Xia Y, Chen X, Chen B, Xia H, Xu C, Li F, Xu X, Al-Aama JY, Yang H, Wang J, Kristiansen K, Wang J, Steves CJ, Bell JT, Li J, Spector TD, Jia H.

Cell Syst. 2016 Nov 2. pii: S2405-4712(16)30323-4. doi: 10.1016/j.cels.2016.10.004. [Epub ahead of print]

PMID:
27818083
6.

DNA methylation-based measures of biological age: meta-analysis predicting time to death.

Chen BH, Marioni RE, Colicino E, Peters MJ, Ward-Caviness CK, Tsai PC, Roetker NS, Just AC, Demerath EW, Guan W, Bressler J, Fornage M, Studenski S, Vandiver AR, Moore AZ, Tanaka T, Kiel DP, Liang L, Vokonas P, Schwartz J, Lunetta KL, Murabito JM, Bandinelli S, Hernandez DG, Melzer D, Nalls M, Pilling LC, Price TR, Singleton AB, Gieger C, Holle R, Kretschmer A, Kronenberg F, Kunze S, Linseisen J, Meisinger C, Rathmann W, Waldenberger M, Visscher PM, Shah S, Wray NR, McRae AF, Franco OH, Hofman A, Uitterlinden AG, Absher D, Assimes T, Levine ME, Lu AT, Tsao PS, Hou L, Manson JE, Carty CL, LaCroix AZ, Reiner AP, Spector TD, Feinberg AP, Levy D, Baccarelli A, van Meurs J, Bell JT, Peters A, Deary IJ, Pankow JS, Ferrucci L, Horvath S.

Aging (Albany NY). 2016 Sep 28;8(9):1844-1865. doi: 10.18632/aging.101020.

7.

Heritable components of the human fecal microbiome are associated with visceral fat.

Beaumont M, Goodrich JK, Jackson MA, Yet I, Davenport ER, Vieira-Silva S, Debelius J, Pallister T, Mangino M, Raes J, Knight R, Clark AG, Ley RE, Spector TD, Bell JT.

Genome Biol. 2016 Sep 26;17(1):189.

8.

A heritability-based comparison of methods used to cluster 16S rRNA gene sequences into operational taxonomic units.

Jackson MA, Bell JT, Spector TD, Steves CJ.

PeerJ. 2016 Aug 30;4:e2341. doi: 10.7717/peerj.2341.

9.

Collapsed methylation quantitative trait loci analysis for low frequency and rare variants.

Richardson TG, Shihab HA, Hemani G, Zheng J, Hannon E, Mill J, Carnero-Montoro E, Bell JT, Lyttleton O, McArdle WL, Ring SM, Rodriguez S, Campbell C, Smith GD, Relton CL, Timpson NJ, Gaunt TR.

Hum Mol Genet. 2016 Aug 24. pii: ddw283. [Epub ahead of print]

10.

Genetic Determinants of the Gut Microbiome in UK Twins.

Goodrich JK, Davenport ER, Beaumont M, Jackson MA, Knight R, Ober C, Spector TD, Bell JT, Clark AG, Ley RE.

Cell Host Microbe. 2016 May 11;19(5):731-43. doi: 10.1016/j.chom.2016.04.017.

PMID:
27173935
11.

Contribution of Heritability and Epigenetic Factors to Skeletal Muscle Mass Variation in United Kingdom Twins.

Livshits G, Gao F, Malkin I, Needhamsen M, Xia Y, Yuan W, Bell CG, Ward K, Liu Y, Wang J, Bell JT, Spector TD.

J Clin Endocrinol Metab. 2016 Jun;101(6):2450-9. doi: 10.1210/jc.2016-1219.

12.

Genetic Influences on Metabolite Levels: A Comparison across Metabolomic Platforms.

Yet I, Menni C, Shin SY, Mangino M, Soranzo N, Adamski J, Suhre K, Spector TD, Kastenmüller G, Bell JT.

PLoS One. 2016 Apr 13;11(4):e0153672. doi: 10.1371/journal.pone.0153672.

13.

Erratum to: signatures of early frailty in the gut microbiota.

Jackson MA, Jeffery IB, Beaumont M, Bell JT, Clark AG, Ley RE, O'Toole PW, Spector TD, Steves CJ.

Genome Med. 2016 Feb 17;8(1):21. doi: 10.1186/s13073-016-0275-2. No abstract available.

14.

Signatures of early frailty in the gut microbiota.

Jackson MA, Jeffery IB, Beaumont M, Bell JT, Clark AG, Ley RE, O'Toole PW, Spector TD, Steves CJ.

Genome Med. 2016 Jan 29;8(1):8. doi: 10.1186/s13073-016-0262-7. Erratum in: Genome Med. 2016;8(1):21. Jackson, Matt [corrected to Jackson, Matthew A].

15.

Integrative DNA methylome analysis of pan-cancer biomarkers in cancer discordant monozygotic twin-pairs.

Roos L, van Dongen J, Bell CG, Burri A, Deloukas P, Boomsma DI, Spector TD, Bell JT.

Clin Epigenetics. 2016 Jan 20;8:7. doi: 10.1186/s13148-016-0172-y.

16.

Proton pump inhibitors alter the composition of the gut microbiota.

Jackson MA, Goodrich JK, Maxan ME, Freedberg DE, Abrams JA, Poole AC, Sutter JL, Welter D, Ley RE, Bell JT, Spector TD, Steves CJ.

Gut. 2016 May;65(5):749-56. doi: 10.1136/gutjnl-2015-310861. Erratum in: Nat Rev Gastroenterol Hepatol. 2016 Apr;13(4):188.

17.

Population whole-genome bisulfite sequencing across two tissues highlights the environment as the principal source of human methylome variation.

Busche S, Shao X, Caron M, Kwan T, Allum F, Cheung WA, Ge B, Westfall S, Simon MM; Multiple Tissue Human Expression Resource., Barrett A, Bell JT, McCarthy MI, Deloukas P, Blanchette M, Bourque G, Spector TD, Lathrop M, Pastinen T, Grundberg E.

Genome Biol. 2015 Dec 23;16:290. doi: 10.1186/s13059-015-0856-1.

18.

Genetic and environmental impacts on DNA methylation levels in twins.

Yet I, Tsai PC, Castillo-Fernandez JE, Carnero-Montoro E, Bell JT.

Epigenomics. 2016 Jan;8(1):105-17. doi: 10.2217/epi.15.90. Review.

PMID:
26678685
19.

DNA Methylation Changes in the IGF1R Gene in Birth Weight Discordant Adult Monozygotic Twins.

Tsai PC, Van Dongen J, Tan Q, Willemsen G, Christiansen L, Boomsma DI, Spector TD, Valdes AM, Bell JT.

Twin Res Hum Genet. 2015 Dec;18(6):635-46. doi: 10.1017/thg.2015.76.

PMID:
26563994
20.

Host genetic variation impacts microbiome composition across human body sites.

Blekhman R, Goodrich JK, Huang K, Sun Q, Bukowski R, Bell JT, Spector TD, Keinan A, Ley RE, Gevers D, Clark AG.

Genome Biol. 2015 Sep 15;16:191. doi: 10.1186/s13059-015-0759-1.

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