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Items: 1 to 20 of 59

1.

Toll-like receptor 9 activation potentiates interferon-γ-mediated immunopathology in a murine model of Macrophage Activation Syndrome.

Weaver LK, Chu N, Behrens EM.

Arthritis Rheumatol. 2018 Aug 2. doi: 10.1002/art.40683. [Epub ahead of print]

PMID:
30073799
2.

Tyrosine 870 of TLR9 is critical for receptor maturation rather than phosphorylation-dependent ligand-induced signaling.

Biswas C, Rao S, Slade K, Hyman D, Dersh D, Mantegazza AR, Zoltick PW, Marks MS, Argon Y, Behrens EM.

PLoS One. 2018 Jul 19;13(7):e0200913. doi: 10.1371/journal.pone.0200913. eCollection 2018.

3.

CD8 T Cell Memory Increases Immunopathology in the Perforin-Deficient Model of Hemophagocytic Lymphohistiocytosis Secondary to TNF-α.

Taylor MD, Burn TN, Wherry EJ, Behrens EM.

Immunohorizons. 2018 Feb;2(2):67-73. doi: 10.4049/immunohorizons.1800003.

4.

Muscularis macrophage development in the absence of an enteric nervous system.

Avetisyan M, Rood JE, Huerta Lopez S, Sengupta R, Wright-Jin E, Dougherty JD, Behrens EM, Heuckeroth RO.

Proc Natl Acad Sci U S A. 2018 May 1;115(18):4696-4701. doi: 10.1073/pnas.1802490115. Epub 2018 Apr 17.

PMID:
29666241
5.

Indeterminate pediatric acute liver failure is uniquely characterized by a CD103+ CD8+ T-cell infiltrate.

Chapin CA, Burn T, Meijome T, Loomes KM, Melin-Aldana H, Kreiger PA, Whitington PF, Behrens EM, Alonso EM.

Hepatology. 2018 Sep;68(3):1087-1100. doi: 10.1002/hep.29901. Epub 2018 Jul 23.

PMID:
29603342
6.

ECSIT links TLR and BMP signaling in FOP connective tissue progenitor cells.

Wang H, Behrens EM, Pignolo RJ, Kaplan FS.

Bone. 2018 Apr;109:201-209. doi: 10.1016/j.bone.2017.12.024. Epub 2017 Dec 27.

PMID:
29288875
7.

Weathering the storm: Improving therapeutic interventions for cytokine storm syndromes by targeting disease pathogenesis.

Weaver LK, Behrens EM.

Curr Treatm Opt Rheumatol. 2017 Mar;3(1):33-48. doi: 10.1007/s40674-017-0059-x. Epub 2017 Feb 7.

8.

Reply.

Canna SW, Girard C, Malle L, de Jesus A, Romberg N, Kelsen J, Surrey LF, Russo P, Sleight A, Schiffrin E, Gabay C, Goldbach-Mansky R, Behrens EM.

J Allergy Clin Immunol. 2017 Jul;140(1):316-317. doi: 10.1016/j.jaci.2017.03.016. Epub 2017 Apr 29. No abstract available.

PMID:
28460789
9.

Review: Cytokine Storm Syndrome: Looking Toward the Precision Medicine Era.

Behrens EM, Koretzky GA.

Arthritis Rheumatol. 2017 Jun;69(6):1135-1143. doi: 10.1002/art.40071. Review. No abstract available.

10.

IL-10 distinguishes a unique population of activated, effector-like CD8+ T cells in murine acute liver inflammation.

Rood JE, Canna SW, Weaver LK, Tobias JW, Behrens EM.

J Leukoc Biol. 2017 Apr;101(4):1037-1044. doi: 10.1189/jlb.3A0916-221RR. Epub 2016 Dec 29.

11.

Life-threatening NLRC4-associated hyperinflammation successfully treated with IL-18 inhibition.

Canna SW, Girard C, Malle L, de Jesus A, Romberg N, Kelsen J, Surrey LF, Russo P, Sleight A, Schiffrin E, Gabay C, Goldbach-Mansky R, Behrens EM.

J Allergy Clin Immunol. 2017 May;139(5):1698-1701. doi: 10.1016/j.jaci.2016.10.022. Epub 2016 Nov 19. No abstract available.

12.

Pediatric acute liver failure of undetermined cause: A research workshop.

Alonso EM, Horslen SP, Behrens EM, Doo E.

Hepatology. 2017 Mar;65(3):1026-1037. doi: 10.1002/hep.28944. Epub 2017 Jan 6. Review.

13.

Editorial: Caught in the Act: Dissecting Natural Killer Cell Function in Systemic Juvenile Idiopathic Arthritis.

Behrens EM.

Arthritis Rheumatol. 2017 Jan;69(1):6-8. doi: 10.1002/art.39934. No abstract available.

14.

TLR9-mediated inflammation drives a Ccr2-independent peripheral monocytosis through enhanced extramedullary monocytopoiesis.

Weaver LK, Chu N, Behrens EM.

Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):10944-9. doi: 10.1073/pnas.1524487113. Epub 2016 Sep 12.

15.

Variants in CXCR4 associate with juvenile idiopathic arthritis susceptibility.

Finkel TH, Li J, Wei Z, Wang W, Zhang H, Behrens EM, Reuschel EL, Limou S, Wise C, Punaro M, Becker ML, Munro JE, Flatø B, Førre Ø, Thompson SD, Langefeld CD, Glass DN, Glessner JT, Kim CE, Frackelton E, Shivers DK, Thomas KA, Chiavacci RM, Hou C, Xu K, Snyder J, Qiu H, Mentch F, Wang K, Winkler CA, Lie BA, Ellis JA, Hakonarson H.

BMC Med Genet. 2016 Mar 22;17:24. doi: 10.1186/s12881-016-0285-3.

16.

2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis: A European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Collaborative Initiative.

Ravelli A, Minoia F, Davì S, Horne A, Bovis F, Pistorio A, Aricò M, Avcin T, Behrens EM, De Benedetti F, Filipovic L, Grom AA, Henter JI, Ilowite NT, Jordan MB, Khubchandani R, Kitoh T, Lehmberg K, Lovell DJ, Miettunen P, Nichols KE, Ozen S, Pachlopnik Schmid J, Ramanan AV, Russo R, Schneider R, Sterba G, Uziel Y, Wallace C, Wouters C, Wulffraat N, Demirkaya E, Brunner HI, Martini A, Ruperto N, Cron RQ; Paediatric Rheumatology International Trials Organisation; Childhood Arthritis and Rheumatology Research Alliance; Pediatric Rheumatology Collaborative Study Group; Histiocyte Society.

Ann Rheum Dis. 2016 Mar;75(3):481-9. doi: 10.1136/annrheumdis-2015-208982.

PMID:
26865703
17.

Expert consensus on dynamics of laboratory tests for diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.

Ravelli A, Minoia F, Davì S, Horne A, Bovis F, Pistorio A, Aricò M, Avcin T, Behrens EM, De Benedetti F, Filipovic A, Grom AA, Henter JI, Ilowite NT, Jordan MB, Khubchandani R, Kitoh T, Lehmberg K, Lovell DJ, Miettunen P, Nichols KE, Ozen S, Pachlopnik Schmid J, Ramanan AV, Russo R, Schneider R, Sterba G, Uziel Y, Wallace C, Wouters C, Wulffraat N, Demirkaya E, Brunner HI, Martini A, Ruperto N, Cron RQ.

RMD Open. 2016 Jan 19;2(1):e000161. doi: 10.1136/rmdopen-2015-000161. eCollection 2016.

18.

Janus kinase inhibition lessens inflammation and ameliorates disease in murine models of hemophagocytic lymphohistiocytosis.

Das R, Guan P, Sprague L, Verbist K, Tedrick P, An QA, Cheng C, Kurachi M, Levine R, Wherry EJ, Canna SW, Behrens EM, Nichols KE.

Blood. 2016 Mar 31;127(13):1666-75. doi: 10.1182/blood-2015-12-684399. Epub 2016 Jan 29.

19.

ST2 contributes to T-cell hyperactivation and fatal hemophagocytic lymphohistiocytosis in mice.

Rood JE, Rao S, Paessler M, Kreiger PA, Chu N, Stelekati E, Wherry EJ, Behrens EM.

Blood. 2016 Jan 28;127(4):426-35. doi: 10.1182/blood-2015-07-659813. Epub 2015 Oct 30.

20.

BIRC4 Mutation: An Important Rare Cause of Uveitis.

Basiaga ML, Weiss PF, Behrens EM.

J Clin Rheumatol. 2015 Dec;21(8):444-7. doi: 10.1097/RHU.0000000000000327.

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