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Items: 1 to 20 of 28


Antibiotic Cycling and Antibiotic Mixing: Which One Best Mitigates Antibiotic Resistance?

Beardmore RE, Peña-Miller R, Gori F, Iredell J.

Mol Biol Evol. 2017 Apr 1;34(4):802-817. doi: 10.1093/molbev/msw292.


Kinase Inhibition Leads to Hormesis in a Dual Phosphorylation-Dephosphorylation Cycle.

Rashkov P, Barrett IP, Beardmore RE, Bendtsen C, Gudelj I.

PLoS Comput Biol. 2016 Nov 29;12(11):e1005216. doi: 10.1371/journal.pcbi.1005216. eCollection 2016 Nov.


Keele Aches and Pains Study protocol: validity, acceptability, and feasibility of the Keele STarT MSK tool for subgrouping musculoskeletal patients in primary care.

Campbell P, Hill JC, Protheroe J, Afolabi EK, Lewis M, Beardmore R, Hay EM, Mallen CD, Bartlam B, Saunders B, van der Windt DA, Jowett S, Foster NE, Dunn KM.

J Pain Res. 2016 Oct 14;9:807-818. eCollection 2016.


Temporal variation in antibiotic environments slows down resistance evolution in pathogenic Pseudomonas aeruginosa.

Roemhild R, Barbosa C, Beardmore RE, Jansen G, Schulenburg H.

Evol Appl. 2015 Dec;8(10):945-55. doi: 10.1111/eva.12330. Epub 2015 Oct 7.


Using a sequential regimen to eliminate bacteria at sublethal antibiotic dosages.

Fuentes-Hernandez A, Plucain J, Gori F, Pena-Miller R, Reding C, Jansen G, Schulenburg H, Gudelj I, Beardmore R.

PLoS Biol. 2015 Apr 8;13(4):e1002104. doi: 10.1371/journal.pbio.1002104. eCollection 2015 Apr.


Biophysical mechanisms that maintain biodiversity through trade-offs.

Meyer JR, Gudelj I, Beardmore R.

Nat Commun. 2015 Feb 19;6:6278. doi: 10.1038/ncomms7278.


Bistable expression of virulence genes in salmonella leads to the formation of an antibiotic-tolerant subpopulation.

Arnoldini M, Vizcarra IA, Peña-Miller R, Stocker N, Diard M, Vogel V, Beardmore RE, Hardt WD, Ackermann M.

PLoS Biol. 2014 Aug 19;12(8):e1001928. doi: 10.1371/journal.pbio.1001928. eCollection 2014 Aug.


Genomics of rapid adaptation to antibiotics: convergent evolution and scalable sequence amplification.

Laehnemann D, Peña-Miller R, Rosenstiel P, Beardmore R, Jansen G, Schulenburg H.

Genome Biol Evol. 2014 May 20;6(6):1287-301. doi: 10.1093/gbe/evu106.


Testing the optimality properties of a dual antibiotic treatment in a two-locus, two-allele model.

Peña-Miller R, Fuentes-Hernandez A, Reding C, Gudelj I, Beardmore R.

J R Soc Interface. 2014 May 8;11(96):20131035. doi: 10.1098/rsif.2013.1035. Print 2014 Jul 6.


The form of a trade-off determines the response to competition.

Maharjan R, Nilsson S, Sung J, Haynes K, Beardmore RE, Hurst LD, Ferenci T, Gudelj I.

Ecol Lett. 2013 Oct;16(10):1267-76. doi: 10.1111/ele.12159. Epub 2013 Jul 31.


When the most potent combination of antibiotics selects for the greatest bacterial load: the smile-frown transition.

Pena-Miller R, Laehnemann D, Jansen G, Fuentes-Hernandez A, Rosenstiel P, Schulenburg H, Beardmore R.

PLoS Biol. 2013;11(4):e1001540. doi: 10.1371/journal.pbio.1001540. Epub 2013 Apr 23.


The optimal deployment of synergistic antibiotics: a control-theoretic approach.

Peña-Miller R, Lähnemann D, Schulenburg H, Ackermann M, Beardmore R.

J R Soc Interface. 2012 Oct 7;9(75):2488-502. doi: 10.1098/rsif.2012.0279. Epub 2012 May 23.


Clinical course, characteristics and prognostic indicators in patients presenting with back and leg pain in primary care. The ATLAS study protocol.

Konstantinou K, Beardmore R, Dunn KM, Lewis M, Hider SL, Sanders T, Jowett S, Somerville S, Stynes S, van der Windt DA, Vogel S, Hay EM.

BMC Musculoskelet Disord. 2012 Jan 20;13:4. doi: 10.1186/1471-2474-13-4.


Assessing fidelity to integrated motivational interviewing and CBT therapy for psychosis and substance use: the MI-CBT fidelity scale (MI-CTS).

Haddock G, Beardmore R, Earnshaw P, Fitzsimmons M, Nothard S, Butler R, Eisner E, Barrowclough C.

J Ment Health. 2012 Feb;21(1):38-48. doi: 10.3109/09638237.2011.621470.


Selecting against antibiotic-resistant pathogens: optimal treatments in the presence of commensal bacteria.

Peña-Miller R, Lähnemann D, Schulenburg H, Ackermann M, Beardmore R.

Bull Math Biol. 2012 Apr;74(4):908-34. doi: 10.1007/s11538-011-9698-5. Epub 2011 Nov 5.


Development of an assessment schedule for patients with low back-associated leg pain in primary care: a Delphi consensus study.

Konstantinou K, Hider SL, Vogel S, Beardmore R, Somerville S.

Eur Spine J. 2012 Jul;21(7):1241-9. doi: 10.1007/s00586-011-2057-2. Epub 2011 Nov 4.


Does change in cannabis use in established psychosis affect clinical outcome?

Barrowclough C, Emsley R, Eisner E, Beardmore R, Wykes T.

Schizophr Bull. 2013 Mar;39(2):339-48. doi: 10.1093/schbul/sbr152. Epub 2011 Oct 29.


Metabolic trade-offs and the maintenance of the fittest and the flattest.

Beardmore RE, Gudelj I, Lipson DA, Hurst LD.

Nature. 2011 Apr 21;472(7343):342-6. doi: 10.1038/nature09905. Epub 2011 Mar 27.


Integrated motivational interviewing and cognitive behavioural therapy for people with psychosis and comorbid substance misuse: randomised controlled trial.

Barrowclough C, Haddock G, Wykes T, Beardmore R, Conrod P, Craig T, Davies L, Dunn G, Eisner E, Lewis S, Moring J, Steel C, Tarrier N.

BMJ. 2010 Nov 24;341:c6325. doi: 10.1136/bmj.c6325.


Antibiotic cycling versus mixing: the difficulty of using mathematical models to definitively quantify their relative merits.

Beardmore RE, Pena-Miller R.

Math Biosci Eng. 2010 Oct;7(4):923-33. doi: 10.3934/mbe.2010.7.923.


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