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Items: 1 to 20 of 132

1.

Alterations in peripheral fatty acid composition in bipolar and unipolar depression.

Scola G, Versace A, Metherel AH, Monsalve-Castro LA, Phillips ML, Bazinet RP, Andreazza AC.

J Affect Disord. 2018 Jan 6. pii: S0165-0327(17)30847-9. doi: 10.1016/j.jad.2017.12.025. [Epub ahead of print]

PMID:
29336895
2.

Brain docosahexaenoic acid uptake and metabolism.

Lacombe RJS, Chouinard-Watkins R, Bazinet RP.

Mol Aspects Med. 2018 Jan 2. pii: S0098-2997(17)30135-8. doi: 10.1016/j.mam.2017.12.004. [Epub ahead of print] Review.

PMID:
29305120
3.

Association of NEFA composition with insulin sensitivity and beta cell function in the Prospective Metabolism and Islet Cell Evaluation (PROMISE) cohort.

Johnston LW, Harris SB, Retnakaran R, Giacca A, Liu Z, Bazinet RP, Hanley AJ.

Diabetologia. 2017 Dec 24. doi: 10.1007/s00125-017-4534-6. [Epub ahead of print]

PMID:
29275428
4.

Markers of microglia in post-mortem brain samples from patients with Alzheimer's disease: a systematic review.

Hopperton KE, Mohammad D, Trépanier MO, Giuliano V, Bazinet RP.

Mol Psychiatry. 2017 Dec 12. doi: 10.1038/mp.2017.246. [Epub ahead of print] Review.

PMID:
29230021
5.

Complete assessment of whole-body n-3 and n-6 PUFA synthesis-secretion kinetics and DHA turnover in a rodent model.

Metherel AH, Lacombe RJS, Chouinard-Watkins RE, Hopperton KE, Bazinet RP.

J Lipid Res. 2017 Dec 11. pii: jlr.M081380. doi: 10.1194/jlr.M081380. [Epub ahead of print]

6.

Anti-Inflammatory Effects of Omega-3 Fatty Acids in the Brain: Physiological Mechanisms and Relevance to Pharmacology.

Layé S, Nadjar A, Joffre C, Bazinet RP.

Pharmacol Rev. 2018 Jan;70(1):12-38. doi: 10.1124/pr.117.014092. Review.

PMID:
29217656
7.

Retroconversion is a minor contributor to increases in eicosapentaenoic acid following docosahexaenoic acid feeding as determined by compound specific isotope analysis in rat liver.

Metherel AH, Chouinard-Watkins R, Trépanier MO, Lacombe RJS, Bazinet RP.

Nutr Metab (Lond). 2017 Nov 28;14:75. doi: 10.1186/s12986-017-0230-2. eCollection 2017.

8.

Mechanisms regulating brain docosahexaenoic acid uptake: what is the recent evidence?

Chouinard-Watkins R, Lacombe RJS, Bazinet RP.

Curr Opin Clin Nutr Metab Care. 2017 Dec 4. doi: 10.1097/MCO.0000000000000440. [Epub ahead of print]

PMID:
29206690
9.

Dietary fish oil, and to a lesser extent the fat-1 transgene, increases astrocyte activation in response to intracerebroventricular amyloid-β 1-40 in mice.

Hopperton KE, James NCE, Mohammad D, Irfan M, Bazinet RP.

Nutr Neurosci. 2017 Nov 7:1-7. doi: 10.1080/1028415X.2017.1396068. [Epub ahead of print]

PMID:
29113539
10.

Fish oil feeding attenuates neuroinflammatory gene expression without concomitant changes in brain eicosanoids and docosanoids in a mouse model of Alzheimer's disease.

Hopperton KE, Trépanier MO, James NCE, Chouinard-Watkins R, Bazinet RP.

Brain Behav Immun. 2017 Nov 3. pii: S0889-1591(17)30485-3. doi: 10.1016/j.bbi.2017.11.002. [Epub ahead of print]

PMID:
29109025
11.

Chronic fluoxetine upregulates activity, protein and mRNA levels of cytosolic phospholipase A2 in rat frontal cortex.

Rao JS, Ertley RN, Lee HJ, Rapoport SI, Bazinet RP.

Pharmacogenomics J. 2017 Dec;17(6):563. doi: 10.1038/tpj.2017.42. Epub 2017 Oct 17.

PMID:
29053139
12.

Docosahexaenoic acid (DHA) accretion in the placenta but not the fetus is matched by plasma unesterified DHA uptake rates in pregnant Long Evans rats.

Metherel AH, Kitson AP, Domenichiello AF, Lacombe RJS, Hopperton KE, Trépanier MO, Alashmali SM, Lin L, Bazinet RP.

Placenta. 2017 Oct;58:90-97. doi: 10.1016/j.placenta.2017.08.072. Epub 2017 Sep 1.

PMID:
28962703
13.

n-3 polyunsaturated fatty acid deprivation in rats decreases frontal cortex BDNF via a p38 MAPK-dependent mechanism.

Rao JS, Ertley RN, Lee HJ, DeMar JC Jr, Arnold JT, Rapoport SI, Bazinet RP.

Mol Psychiatry. 2017 Sep 26. doi: 10.1038/mp.2017.199. [Epub ahead of print] No abstract available.

PMID:
28948969
14.

Individual serum saturated fatty acids and markers of chronic subclinical inflammation: the Insulin Resistance Atherosclerosis Study.

Santaren ID, Watkins SM, Liese AD, Wagenknecht LE, Rewers MJ, Haffner SM, Lorenzo C, Festa A, Bazinet RP, Hanley AJ.

J Lipid Res. 2017 Nov;58(11):2171-2179. doi: 10.1194/jlr.P076836. Epub 2017 Sep 19.

PMID:
28928169
15.

Maternal dietary n-6 polyunsaturated fatty acid deprivation does not exacerbate post-weaning reductions in arachidonic acid and its mediators in the mouse hippocampus.

Alashmali SM, Kitson AP, Lin L, Lacombe RJS, Bazinet RP.

Nutr Neurosci. 2017 Sep 13:1-12. doi: 10.1080/1028415X.2017.1372160. [Epub ahead of print]

PMID:
28903622
16.

Macrophage JAK2 deficiency protects against high-fat diet-induced inflammation.

Desai HR, Sivasubramaniyam T, Revelo XS, Schroer SA, Luk CT, Rikkala PR, Metherel AH, Dodington DW, Park YJ, Kim MJ, Rapps JA, Besla R, Robbins CS, Wagner KU, Bazinet RP, Winer DA, Woo M.

Sci Rep. 2017 Aug 9;7(1):7653. doi: 10.1038/s41598-017-07923-0.

17.

Phospholipid class-specific brain enrichment in response to lysophosphatidylcholine docosahexaenoic acid infusion.

Chouinard-Watkins R, Chen CT, Metherel AH, Lacombe RJS, Thies F, Masoodi M, Bazinet RP.

Biochim Biophys Acta. 2017 Oct;1862(10 Pt A):1092-1098. doi: 10.1016/j.bbalip.2017.07.013. Epub 2017 Jul 28.

PMID:
28760485
18.

Hepatic JAK2 protects against atherosclerosis through circulating IGF-1.

Sivasubramaniyam T, Schroer SA, Li A, Luk CT, Shi SY, Besla R, Dodington DW, Metherel AH, Kitson AP, Brunt JJ, Lopes J, Wagner KU, Bazinet RP, Bendeck MP, Robbins CS, Woo M.

JCI Insight. 2017 Jul 20;2(14). pii: 93735. doi: 10.1172/jci.insight.93735. [Epub ahead of print]

19.

Compound-specific isotope analysis resolves the dietary origin of docosahexaenoic acid in the mouse brain.

Lacombe RJS, Giuliano V, Colombo SM, Arts MT, Bazinet RP.

J Lipid Res. 2017 Oct;58(10):2071-2081. doi: 10.1194/jlr.D077990. Epub 2017 Jul 10.

PMID:
28694298
20.

Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission.

Hennebelle M, Zhang Z, Metherel AH, Kitson AP, Otoki Y, Richardson CE, Yang J, Lee KSS, Hammock BD, Zhang L, Bazinet RP, Taha AY.

Sci Rep. 2017 Jun 28;7(1):4342. doi: 10.1038/s41598-017-02914-7.

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