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Items: 1 to 20 of 52


Profiling of metalloprotease activities in cerebrospinal fluids of patients with neoplastic meningitis.

Conrad C, Dorzweiler K, Miller MA, Lauffenburger DA, Strik H, Bartsch JW.

Fluids Barriers CNS. 2017 Aug 14;14(1):22. doi: 10.1186/s12987-017-0070-5.


The metalloproteinase ADAM8 promotes leukocyte recruitment in vitro and in acute lung inflammation.

Dreymueller D, Pruessmeyer J, Schumacher J, Fellendorf S, Hess FM, Seifert A, Babendreyer A, Bartsch JW, Ludwig A.

Am J Physiol Lung Cell Mol Physiol. 2017 Jun 8:ajplung.00444.2016. doi: 10.1152/ajplung.00444.2016. [Epub ahead of print]


Simultaneous Detection of Metalloprotease Activities in Complex Biological Samples Using the PrAMA (Proteolytic Activity Matrix Assay) Method.

Conrad C, Miller MA, Bartsch JW, Schlomann U, Lauffenburger DA.

Methods Mol Biol. 2017;1574:243-253. doi: 10.1007/978-1-4939-6850-3_18.


Nrf2- and Bach1 May Play a Role in the Modulation of Ultraviolet A-Induced Oxidative Stress by Acetyl-11-Keto-β-Boswellic Acid in Skin Keratinocytes.

Yang S, Zhou B, Xu W, Xue F, Nisar MF, Bian C, Huang X, Yang L, Zhang Y, Bartsch JW, Zhong JL.

Skin Pharmacol Physiol. 2017;30(1):13-23. doi: 10.1159/000452744. Epub 2017 Feb 1.


Expression of the zinc importer protein ZIP9/SLC39A9 in glioblastoma cells affects phosphorylation states of p53 and GSK-3β and causes increased cell migration.

Münnich N, Wernhart S, Hogstrand C, Schlomann U, Nimsky C, Bartsch JW.

Biometals. 2016 Dec;29(6):995-1004. Epub 2016 Sep 21.


A novel peptide ADAM8 inhibitor attenuates bronchial hyperresponsiveness and Th2 cytokine mediated inflammation of murine asthmatic models.

Chen J, Deng L, Dreymüller D, Jiang X, Long J, Duan Y, Wang Y, Luo M, Lin F, Mao L, Müller B, Koller G, Bartsch JW.

Sci Rep. 2016 Jul 26;6:30451. doi: 10.1038/srep30451.


Synthesis and biological evaluation of analogues of the potent ADAM8 inhibitor cyclo(RLsKDK) for the treatment of inflammatory diseases and cancer metastasis.

Yim V, Noisier AFM, Hung KY, Bartsch JW, Schlomann U, Brimble MA.

Bioorg Med Chem. 2016 Sep 15;24(18):4032-4037. doi: 10.1016/j.bmc.2016.06.042. Epub 2016 Jun 23.


Metalloproteinases ADAM12 and MMP-14 are associated with cavernous sinus invasion in pituitary adenomas.

Wang J, Voellger B, Benzel J, Schlomann U, Nimsky C, Bartsch JW, Carl B.

Int J Cancer. 2016 Sep 15;139(6):1327-39. doi: 10.1002/ijc.30173. Epub 2016 May 24.


Shedding of Endogenous Interleukin-6 Receptor (IL-6R) Is Governed by A Disintegrin and Metalloproteinase (ADAM) Proteases while a Full-length IL-6R Isoform Localizes to Circulating Microvesicles.

Schumacher N, Meyer D, Mauermann A, von der Heyde J, Wolf J, Schwarz J, Knittler K, Murphy G, Michalek M, Garbers C, Bartsch JW, Guo S, Schacher B, Eickholz P, Chalaris A, Rose-John S, Rabe B.

J Biol Chem. 2015 Oct 23;290(43):26059-71. doi: 10.1074/jbc.M115.649509. Epub 2015 Sep 10.


Correlation of ghrelin and growth hormone secretagogue receptor expression with clinical features in human pituitary adenomas.

Wang J, Guo S, Han L, Fang M, Wang L, Bartsch JW, Li J.

Exp Ther Med. 2015 May;9(5):1909-1914. Epub 2015 Mar 11.


A colorimetric-based amplification system for proteinases including MMP2 and ADAM8.

Moss ML, Koller G, Bartsch JW, Rakow S, Schlomann U, Rasmussen FH.

Anal Biochem. 2015 Sep 1;484:75-81. doi: 10.1016/j.ab.2015.05.011. Epub 2015 May 27.


The metalloprotease-disintegrin ADAM8 contributes to temozolomide chemoresistance and enhanced invasiveness of human glioblastoma cells.

Dong F, Eibach M, Bartsch JW, Dolga AM, Schlomann U, Conrad C, Schieber S, Schilling O, Biniossek ML, Culmsee C, Strik H, Koller G, Carl B, Nimsky C.

Neuro Oncol. 2015 Nov;17(11):1474-85. doi: 10.1093/neuonc/nov042. Epub 2015 Mar 29.


An MMP-inhibitor modified adhesive primer enhances bond durability to carious dentin.

Almahdy A, Koller G, Festy F, Bartsch JW, Watson TF, Banerjee A.

Dent Mater. 2015 May;31(5):594-602. doi: 10.1016/ Epub 2015 Mar 21.


ADAM8 as a drug target in pancreatic cancer.

Schlomann U, Koller G, Conrad C, Ferdous T, Golfi P, Garcia AM, Höfling S, Parsons M, Costa P, Soper R, Bossard M, Hagemann T, Roshani R, Sewald N, Ketchem RR, Moss ML, Rasmussen FH, Miller MA, Lauffenburger DA, Tuveson DA, Nimsky C, Bartsch JW.

Nat Commun. 2015 Jan 28;6:6175. doi: 10.1038/ncomms7175.


Roles of ADAM8 in elimination of injured muscle fibers prior to skeletal muscle regeneration.

Nishimura D, Sakai H, Sato T, Sato F, Nishimura S, Toyama-Sorimachi N, Bartsch JW, Sehara-Fujisawa A.

Mech Dev. 2015 Feb;135:58-67. doi: 10.1016/j.mod.2014.12.001. Epub 2014 Dec 12.


ADAM8 expression in invasive breast cancer promotes tumor dissemination and metastasis.

Romagnoli M, Mineva ND, Polmear M, Conrad C, Srinivasan S, Loussouarn D, Barillé-Nion S, Georgakoudi I, Dagg Á, McDermott EW, Duffy MJ, McGowan PM, Schlomann U, Parsons M, Bartsch JW, Sonenshein GE.

EMBO Mol Med. 2014 Feb;6(2):278-94. doi: 10.1002/emmm.201303373. Epub 2013 Dec 27.


ADAM8 in asthma. Friend or foe to airway inflammation?

Chen J, Jiang X, Duan Y, Long J, Bartsch JW, Deng L.

Am J Respir Cell Mol Biol. 2013 Dec;49(6):875-84. doi: 10.1165/rcmb.2013-0168TR. Review.


Loss of vps54 function leads to vesicle traffic impairment, protein mis-sorting and embryonic lethality.

Karlsson P, Droce A, Moser JM, Cuhlmann S, Padilla CO, Heimann P, Bartsch JW, Füchtbauer A, Füchtbauer EM, Schmitt-John T.

Int J Mol Sci. 2013 May 24;14(6):10908-25. doi: 10.3390/ijms140610908.


Axonal growth towards Xenopus skin in vitro is mediated by matrix metalloproteinase activity.

Tonge D, Zhu N, Lynham S, Leclere P, Snape A, Brewer A, Schlomann U, Ferdous T, Tennyson C, Bartsch JW, Ward M, Pizzey J.

Eur J Neurosci. 2013 Feb;37(4):519-31. doi: 10.1111/ejn.12075. Epub 2012 Dec 6.


Effects of MMP inhibitors incorporated within dental adhesives.

Almahdy A, Koller G, Sauro S, Bartsch JW, Sherriff M, Watson TF, Banerjee A.

J Dent Res. 2012 Jun;91(6):605-11. doi: 10.1177/0022034512446339. Epub 2012 Apr 18.

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