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Items: 10


Inhibiting glycogen synthesis prevents Lafora disease in a mouse model.

Pederson BA, Turnbull J, Epp JR, Weaver SA, Zhao X, Pencea N, Roach PJ, Frankland PW, Ackerley CA, Minassian BA.

Ann Neurol. 2013 Aug;74(2):297-300. doi: 10.1002/ana.23899.


Brain glycogen supercompensation in the mouse after recovery from insulin-induced hypoglycemia.

Canada SE, Weaver SA, Sharpe SN, Pederson BA.

J Neurosci Res. 2011 Apr;89(4):585-91. doi: 10.1002/jnr.22579. Epub 2011 Jan 21.


A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice.

Savage DB, Zhai L, Ravikumar B, Choi CS, Snaar JE, McGuire AC, Wou SE, Medina-Gomez G, Kim S, Bock CB, Segvich DM, Solanky B, Deelchand D, Vidal-Puig A, Wareham NJ, Shulman GI, Karpe F, Taylor R, Pederson BA, Roach PJ, O'Rahilly S, DePaoli-Roach AA.

PLoS Med. 2008 Jan 29;5(1):e27. doi: 10.1371/journal.pmed.0050027. Erratum in: PLoS Med. 2008 Dec;5(12):e246.. Solanky, Bhavana [added]; Deelchand, Dinesh [added].


Gene expression profiling of mice with genetically modified muscle glycogen content.

Parker GE, Pederson BA, Obayashi M, Schroeder JM, Harris RA, Roach PJ.

Biochem J. 2006 Apr 1;395(1):137-45.


Glucose metabolism in mice lacking muscle glycogen synthase.

Pederson BA, Schroeder JM, Parker GE, Smith MW, DePaoli-Roach AA, Roach PJ.

Diabetes. 2005 Dec;54(12):3466-73.


Mice with elevated muscle glycogen stores do not have improved exercise performance.

Pederson BA, Cope CR, Irimia JM, Schroeder JM, Thurberg BL, Depaoli-Roach AA, Roach PJ.

Biochem Biophys Res Commun. 2005 Jun 3;331(2):491-6.


Exercise capacity of mice genetically lacking muscle glycogen synthase: in mice, muscle glycogen is not essential for exercise.

Pederson BA, Cope CR, Schroeder JM, Smith MW, Irimia JM, Thurberg BL, DePaoli-Roach AA, Roach PJ.

J Biol Chem. 2005 Apr 29;280(17):17260-5. Epub 2005 Feb 11.


Abnormal cardiac development in the absence of heart glycogen.

Pederson BA, Chen H, Schroeder JM, Shou W, DePaoli-Roach AA, Roach PJ.

Mol Cell Biol. 2004 Aug;24(16):7179-87.


Glycogen synthase sensitivity to glucose-6-P is important for controlling glycogen accumulation in Saccharomyces cerevisiae.

Pederson BA, Wilson WA, Roach PJ.

J Biol Chem. 2004 Apr 2;279(14):13764-8. Epub 2004 Jan 23. Erratum in: J Biol Chem. 2005 Apr 1;280(13):13204.


Overexpression of glycogen synthase in mouse muscle results in less branched glycogen.

Pederson BA, Csitkovits AG, Simon R, Schroeder JM, Wang W, Skurat AV, Roach PJ.

Biochem Biophys Res Commun. 2003 Jun 13;305(4):826-30.


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