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Items: 1 to 20 of 111


Attitudes and opinions regarding confirmatory adaptive clinical trials: a mixed methods analysis from the Adaptive Designs Accelerating Promising Trials into Treatments (ADAPT-IT) project.

Meurer WJ, Legocki L, Mawocha S, Frederiksen SM, Guetterman TC, Barsan W, Lewis R, Berry D, Fetters M.

Trials. 2016 Jul 29;17:373. doi: 10.1186/s13063-016-1493-z.


Hyperbaric oxygen brain injury treatment (HOBIT) trial: a multifactor design with response adaptive randomization and longitudinal modeling.

Gajewski BJ, Berry SM, Barsan WG, Silbergleit R, Meurer WJ, Martin R, Rockswold GL.

Pharm Stat. 2016 Sep;15(5):396-404. doi: 10.1002/pst.1755.


Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage.

Qureshi AI, Palesch YY, Barsan WG, Hanley DF, Hsu CY, Martin RL, Moy CS, Silbergleit R, Steiner T, Suarez JI, Toyoda K, Wang Y, Yamamoto H, Yoon BW; ATACH-2 Trial Investigators and the Neurological Emergency Treatment Trials Network..

N Engl J Med. 2016 Sep 15;375(11):1033-43. doi: 10.1056/NEJMoa1603460.


Assessment of Emergency Medical Services in the Ashanti Region of Ghana.

Mould-Millman NK, Oteng R, Zakariah A, Osei-Ampofo M, Oduro G, Barsan W, Donkor P, Kowalenko T.

Ghana Med J. 2015 Sep;49(3):125-35.


Reflections on the Adaptive Designs Accelerating Promising Trials Into Treatments (ADAPT-IT) Process-Findings from a Qualitative Study.

Guetterman TC, Fetters MD, Legocki LJ, Mawocha S, Barsan WG, Lewis RJ, Berry DA, Meurer WJ.

Clin Res Regul Aff. 2015 Oct 2;32(4):121-130.


Patient Engagement in Neurological Clinical Trials Design: A Conference Summary.

Cobb EM, Meurer W, Harney D, Silbergleit R, Lake BP, Clark C, Gipson D, Barsan W.

Clin Transl Sci. 2015 Dec;8(6):776-8. doi: 10.1111/cts.12297.


Clinical trialist perspectives on the ethics of adaptive clinical trials: a mixed-methods analysis.

Legocki LJ, Meurer WJ, Frederiksen S, Lewis RJ, Durkalski VL, Berry DA, Barsan WG, Fetters MD.

BMC Med Ethics. 2015 May 3;16:27. doi: 10.1186/s12910-015-0022-z.


Neuroprotection in acute brain injury: an up-to-date review.

Stocchetti N, Taccone FS, Citerio G, Pepe PE, Le Roux PD, Oddo M, Polderman KH, Stevens RD, Barsan W, Maas AI, Meyfroidt G, Bell MJ, Silbergleit R, Vespa PM, Faden AI, Helbok R, Tisherman S, Zanier ER, Valenzuela T, Wendon J, Menon DK, Vincent JL.

Crit Care. 2015 Apr 21;19:186. doi: 10.1186/s13054-015-0887-8. Review.


Prehospital use of magnesium sulfate as neuroprotection in acute stroke.

Saver JL, Starkman S, Eckstein M, Stratton SJ, Pratt FD, Hamilton S, Conwit R, Liebeskind DS, Sung G, Kramer I, Moreau G, Goldweber R, Sanossian N; FAST-MAG Investigators and Coordinators..

N Engl J Med. 2015 Feb 5;372(6):528-36. doi: 10.1056/NEJMoa1408827.


Intramuscular midazolam versus intravenous lorazepam for the prehospital treatment of status epilepticus in the pediatric population.

Welch RD, Nicholas K, Durkalski-Mauldin VL, Lowenstein DH, Conwit R, Mahajan PV, Lewandowski C, Silbergleit R; Neurological Emergencies Treatment Trials (NETT) Network Investigators..

Epilepsia. 2015 Feb;56(2):254-62. doi: 10.1111/epi.12905.


Very early administration of progesterone for acute traumatic brain injury.

Wright DW, Yeatts SD, Silbergleit R, Palesch YY, Hertzberg VS, Frankel M, Goldstein FC, Caveney AF, Howlett-Smith H, Bengelink EM, Manley GT, Merck LH, Janis LS, Barsan WG; NETT Investigators..

N Engl J Med. 2014 Dec 25;371(26):2457-66. doi: 10.1056/NEJMoa1404304.


The empirical foundations of telemedicine interventions for chronic disease management.

Bashshur RL, Shannon GW, Smith BR, Alverson DC, Antoniotti N, Barsan WG, Bashshur N, Brown EM, Coye MJ, Doarn CR, Ferguson S, Grigsby J, Krupinski EA, Kvedar JC, Linkous J, Merrell RC, Nesbitt T, Poropatich R, Rheuban KS, Sanders JH, Watson AR, Weinstein RS, Yellowlees P.

Telemed J E Health. 2014 Sep;20(9):769-800. doi: 10.1089/tmj.2014.9981. Review.


Screen failure data in clinical trials: Are screening logs worth it?

Elm JJ, Palesch Y, Easton JD, Lindblad A, Barsan W, Silbergleit R, Conwit R, Dillon C, Farrant M, Battenhouse H, Perlmutter A, Johnston SC.

Clin Trials. 2014 Aug;11(4):467-472.


A systematic review and critical appraisal of quality measures for the emergency care of acute ischemic stroke.

Sauser K, Burke JF, Reeves MJ, Barsan WG, Levine DA.

Ann Emerg Med. 2014 Sep;64(3):235-244.e5. doi: 10.1016/j.annemergmed.2014.01.034. Review.


Degradation of benzodiazepines after 120 days of EMS deployment.

McMullan JT, Jones E, Barnhart B, Denninghoff K, Spaite D, Zaleski E, Silbergleit R; Neurological Emergencies Treatment Trials investigators..

Prehosp Emerg Care. 2014 Jul-Sep;18(3):368-74. doi: 10.3109/10903127.2013.869642.


High-dose albumin treatment for acute ischaemic stroke (ALIAS) Part 2: a randomised, double-blind, phase 3, placebo-controlled trial.

Ginsberg MD, Palesch YY, Hill MD, Martin RH, Moy CS, Barsan WG, Waldman BD, Tamariz D, Ryckborst KJ; ALIAS and Neurological Emergencies Treatment Trials (NETT) Investigators..

Lancet Neurol. 2013 Nov;12(11):1049-58. doi: 10.1016/S1474-4422(13)70223-0.


Platelet-oriented inhibition in new TIA and minor ischemic stroke (POINT) trial: rationale and design.

Johnston SC, Easton JD, Farrant M, Barsan W, Battenhouse H, Conwit R, Dillon C, Elm J, Lindblad A, Morgenstern L, Poisson SN, Palesch Y.

Int J Stroke. 2013 Aug;8(6):479-83. doi: 10.1111/ijs.12129.


Spinal cord injury neuroprotection and the promise of flexible adaptive clinical trials.

Meurer WJ, Barsan WG.

World Neurosurg. 2014 Sep-Oct;82(3-4):e541-6. doi: 10.1016/j.wneu.2013.06.017. Review.


Toward an international initiative for traumatic brain injury research.

Tosetti P, Hicks RR, Theriault E, Phillips A, Koroshetz W, Draghia-Akli R; Workshop Participants..

J Neurotrauma. 2013 Jul 15;30(14):1211-22. doi: 10.1089/neu.2013.2896.


The Stroke Hyperglycemia Insulin Network Effort (SHINE) trial protocol: a randomized, blinded, efficacy trial of standard vs. intensive hyperglycemia management in acute stroke.

Bruno A, Durkalski VL, Hall CE, Juneja R, Barsan WG, Janis S, Meurer WJ, Fansler A, Johnston KC; SHINE investigators..

Int J Stroke. 2014 Feb;9(2):246-51. doi: 10.1111/ijs.12045.

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