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Items: 17


Effects of eltrombopag on platelet count and platelet activation in Wiskott-Aldrich syndrome/X-linked thrombocytopenia.

Gerrits AJ, Leven EA, Frelinger AL 3rd, Brigstocke SL, Berny-Lang MA, Mitchell WB, Revel-Vilk S, Tamary H, Carmichael SL, Barnard MR, Michelson AD, Bussel JB.

Blood. 2015 Sep 10;126(11):1367-78. doi: 10.1182/blood-2014-09-602573. Epub 2015 Jul 29.


Do immature platelet levels in chest pain patients presenting to the emergency department aid in the diagnosis of acute coronary syndrome?

Berny-Lang MA, Darling CE, Frelinger AL 3rd, Barnard MR, Smith CS, Michelson AD.

Int J Lab Hematol. 2015 Feb;37(1):112-9. doi: 10.1111/ijlh.12250. Epub 2014 May 8.


Antiplatelet activity, P2Y₁ and P2Y₁₂ inhibition, and metabolism in plasma of stereoisomers of diadenosine 5',5'″-P¹ ,P⁴-dithio-P²,P³-chloromethylenetetraphosphate.

Chang H, Yanachkov IB, Dix EJ, Yanachkova M, Li Y, Barnard MR, Wright GE, Michelson AD, Frelinger AL 3rd.

PLoS One. 2014 Apr 10;9(4):e94780. doi: 10.1371/journal.pone.0094780. eCollection 2014.


P2Y12 receptor blockade augments glycoprotein IIb-IIIa antagonist inhibition of platelet activation, aggregation, and procoagulant activity.

Berny-Lang MA, Jakubowski JA, Sugidachi A, Barnard MR, Michelson AD, Frelinger AL 3rd.

J Am Heart Assoc. 2013 May 15;2(3):e000026. doi: 10.1161/JAHA.113.000026.


Concurrent acute myeloid leukemia and T lymphoblastic lymphoma in a patient with rearranged PDGFRB genes.

Chang H, Chuang WY, Sun CF, Barnard MR.

Diagn Pathol. 2012 Feb 22;7:19. doi: 10.1186/1746-1596-7-19.


In vivo effects of eltrombopag on platelet function in immune thrombocytopenia: no evidence of platelet activation.

Psaila B, Bussel JB, Linden MD, Babula B, Li Y, Barnard MR, Tate C, Mathur K, Frelinger AL, Michelson AD.

Blood. 2012 Apr 26;119(17):4066-72. doi: 10.1182/blood-2011-11-393900. Epub 2012 Jan 31.


The human endogenous circadian system causes greatest platelet activation during the biological morning independent of behaviors.

Scheer FA, Michelson AD, Frelinger AL 3rd, Evoniuk H, Kelly EE, McCarthy M, Doamekpor LA, Barnard MR, Shea SA.

PLoS One. 2011;6(9):e24549. doi: 10.1371/journal.pone.0024549. Epub 2011 Sep 8.


Differences in platelet function in patients with acute myeloid leukemia and myelodysplasia compared to equally thrombocytopenic patients with immune thrombocytopenia.

Psaila B, Bussel JB, Frelinger AL, Babula B, Linden MD, Li Y, Barnard MR, Tate C, Feldman EJ, Michelson AD.

J Thromb Haemost. 2011 Nov;9(11):2302-10. doi: 10.1111/j.1538-7836.2011.04506.x.


The influence of intermittent hypoxemia on platelet activation in obese patients with obstructive sleep apnea.

Rahangdale S, Yeh SY, Novack V, Stevenson K, Barnard MR, Furman MI, Frelinger AL, Michelson AD, Malhotra A.

J Clin Sleep Med. 2011 Apr 15;7(2):172-8.


Agonist and antagonist effects of diadenosine tetraphosphate, a platelet dense granule constituent, on platelet P2Y1, P2Y12 and P2X1 receptors.

Chang H, Yanachkov IB, Michelson AD, Li Y, Barnard MR, Wright GE, Frelinger AL 3rd.

Thromb Res. 2010 Feb;125(2):159-65. doi: 10.1016/j.thromres.2009.11.006. Epub 2009 Nov 27.


Targeted inhibition of the serotonin 5HT2A receptor improves coronary patency in an in vivo model of recurrent thrombosis.

Przyklenk K, Frelinger AL 3rd, Linden MD, Whittaker P, Li Y, Barnard MR, Adams J, Morgan M, Al-Shamma H, Michelson AD.

J Thromb Haemost. 2010 Feb;8(2):331-40. doi: 10.1111/j.1538-7836.2009.03693.x. Epub 2009 Nov 17.


Effect of adenosine A2 receptor stimulation on platelet activation-aggregation: differences between canine and human models.

Linden MD, Barnard MR, Frelinger AL, Michelson AD, Przyklenk K.

Thromb Res. 2008;121(5):689-98. Epub 2007 Aug 28.


The cleaved peptide of the thrombin receptor is a strong platelet agonist.

Furman MI, Liu L, Benoit SE, Becker RC, Barnard MR, Michelson AD.

Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3082-7.


Nitric oxide released from activated platelets inhibits platelet recruitment.

Freedman JE, Loscalzo J, Barnard MR, Alpert C, Keaney JF, Michelson AD.

J Clin Invest. 1997 Jul 15;100(2):350-6.


In vivo tracking of platelets: circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function.

Michelson AD, Barnard MR, Hechtman HB, MacGregor H, Connolly RJ, Loscalzo J, Valeri CR.

Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11877-82.


Decreased platelet inhibition by nitric oxide in two brothers with a history of arterial thrombosis.

Freedman JE, Loscalzo J, Benoit SE, Valeri CR, Barnard MR, Michelson AD.

J Clin Invest. 1996 Feb 15;97(4):979-87.


Platelet storage results in a redistribution of glycoprotein Ib molecules. Evidence for a large intraplatelet pool of glycoprotein Ib.

Michelson AD, Adelman B, Barnard MR, Carroll E, Handin RI.

J Clin Invest. 1988 Jun;81(6):1734-40.

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