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Items: 1 to 20 of 46

1.

Retinoic acid signaling is dispensable for somatic development and function in the mammalian ovary.

Minkina A, Lindeman RE, Gearhart MD, Chassot AA, Chaboissier MC, Ghyselinck NB, Bardwell VJ, Zarkower D.

Dev Biol. 2017 Apr 15;424(2):208-220. doi: 10.1016/j.ydbio.2017.02.015. Epub 2017 Mar 6.

PMID:
28274610
2.

Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene.

Lefebure M, Tothill RW, Kruse E, Hawkins ED, Shortt J, Matthews GM, Gregory GP, Martin BP, Kelly MJ, Todorovski I, Doyle MA, Lupat R, Li J, Schroeder J, Wall M, Craig S, Poortinga G, Cameron D, Bywater M, Kats L, Gearhart MD, Bardwell VJ, Dickins RA, Hannan RD, Papenfuss AT, Johnstone RW.

Nat Commun. 2017 Mar 6;8:14581. doi: 10.1038/ncomms14581.

3.

DMRT1 Is Required for Mouse Spermatogonial Stem Cell Maintenance and Replenishment.

Zhang T, Oatley J, Bardwell VJ, Zarkower D.

PLoS Genet. 2016 Sep 1;12(9):e1006293. doi: 10.1371/journal.pgen.1006293. eCollection 2016 Sep.

4.

KDM2B Recruitment of the Polycomb Group Complex, PRC1.1, Requires Cooperation between PCGF1 and BCORL1.

Wong SJ, Gearhart MD, Taylor AB, Nanyes DR, Ha DJ, Robinson AK, Artigas JA, Lee OJ, Demeler B, Hart PJ, Bardwell VJ, Kim CA.

Structure. 2016 Oct 4;24(10):1795-1801. doi: 10.1016/j.str.2016.07.011. Epub 2016 Aug 25.

PMID:
27568929
5.

EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis.

Béguelin W, Teater M, Gearhart MD, Calvo Fernández MT, Goldstein RL, Cárdenas MG, Hatzi K, Rosen M, Shen H, Corcoran CM, Hamline MY, Gascoyne RD, Levine RL, Abdel-Wahab O, Licht JD, Shaknovich R, Elemento O, Bardwell VJ, Melnick AM.

Cancer Cell. 2016 Aug 8;30(2):197-213. doi: 10.1016/j.ccell.2016.07.006.

PMID:
27505670
6.

BCOR regulates myeloid cell proliferation and differentiation.

Cao Q, Gearhart MD, Gery S, Shojaee S, Yang H, Sun H, Lin DC, Bai JW, Mead M, Zhao Z, Chen Q, Chien WW, Alkan S, Alpermann T, Haferlach T, Müschen M, Bardwell VJ, Koeffler HP.

Leukemia. 2016 May;30(5):1155-65. doi: 10.1038/leu.2016.2. Epub 2016 Feb 5.

7.

An ancient protein-DNA interaction underlying metazoan sex determination.

Murphy MW, Lee JK, Rojo S, Gearhart MD, Kurahashi K, Banerjee S, Loeuille GA, Bashamboo A, McElreavey K, Zarkower D, Aihara H, Bardwell VJ.

Nat Struct Mol Biol. 2015 Jun;22(6):442-51. doi: 10.1038/nsmb.3032. Epub 2015 May 25.

8.

Cutting edge: Bcl6-interacting corepressor contributes to germinal center T follicular helper cell formation and B cell helper function.

Yang JA, Tubo NJ, Gearhart MD, Bardwell VJ, Jenkins MK.

J Immunol. 2015 Jun 15;194(12):5604-8. doi: 10.4049/jimmunol.1500201. Epub 2015 May 11.

9.

Sexual cell-fate reprogramming in the ovary by DMRT1.

Lindeman RE, Gearhart MD, Minkina A, Krentz AD, Bardwell VJ, Zarkower D.

Curr Biol. 2015 Mar 16;25(6):764-71. doi: 10.1016/j.cub.2015.01.034. Epub 2015 Feb 12.

10.

The mammalian Doublesex homolog DMRT6 coordinates the transition between mitotic and meiotic developmental programs during spermatogenesis.

Zhang T, Murphy MW, Gearhart MD, Bardwell VJ, Zarkower D.

Development. 2014 Oct;141(19):3662-71. doi: 10.1242/dev.113936.

11.

DMRT1 protects male gonadal cells from retinoid-dependent sexual transdifferentiation.

Minkina A, Matson CK, Lindeman RE, Ghyselinck NB, Bardwell VJ, Zarkower D.

Dev Cell. 2014 Jun 9;29(5):511-20. doi: 10.1016/j.devcel.2014.04.017. Epub 2014 May 22.

12.

A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters.

Hatzi K, Jiang Y, Huang C, Garrett-Bakelman F, Gearhart MD, Giannopoulou EG, Zumbo P, Kirouac K, Bhaskara S, Polo JM, Kormaksson M, MacKerell AD Jr, Xue F, Mason CE, Hiebert SW, Prive GG, Cerchietti L, Bardwell VJ, Elemento O, Melnick A.

Cell Rep. 2013 Aug 15;4(3):578-88. doi: 10.1016/j.celrep.2013.06.016. Epub 2013 Aug 1.

13.

Structure of the polycomb group protein PCGF1 in complex with BCOR reveals basis for binding selectivity of PCGF homologs.

Junco SE, Wang R, Gaipa JC, Taylor AB, Schirf V, Gearhart MD, Bardwell VJ, Demeler B, Hart PJ, Kim CA.

Structure. 2013 Apr 2;21(4):665-71. doi: 10.1016/j.str.2013.02.013. Epub 2013 Mar 21.

14.

Interaction between DMRT1 function and genetic background modulates signaling and pluripotency to control tumor susceptibility in the fetal germ line.

Krentz AD, Murphy MW, Zhang T, Sarver AL, Jain S, Griswold MD, Bardwell VJ, Zarkower D.

Dev Biol. 2013 May 1;377(1):67-78. doi: 10.1016/j.ydbio.2013.02.014. Epub 2013 Mar 6.

15.

DMRT1 prevents female reprogramming in the postnatal mammalian testis.

Matson CK, Murphy MW, Sarver AL, Griswold MD, Bardwell VJ, Zarkower D.

Nature. 2011 Jul 20;476(7358):101-4. doi: 10.1038/nature10239. Erratum in: Nature. 2011 Sep 8;477(7363):238.

16.

DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary.

Krentz AD, Murphy MW, Sarver AL, Griswold MD, Bardwell VJ, Zarkower D.

Dev Biol. 2011 Aug 1;356(1):63-70. doi: 10.1016/j.ydbio.2011.05.658. Epub 2011 May 20.

17.

The mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells.

Matson CK, Murphy MW, Griswold MD, Yoshida S, Bardwell VJ, Zarkower D.

Dev Cell. 2010 Oct 19;19(4):612-24. doi: 10.1016/j.devcel.2010.09.010.

18.

Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis.

Murphy MW, Sarver AL, Rice D, Hatzi K, Ye K, Melnick A, Heckert LL, Zarkower D, Bardwell VJ.

Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13360-5. doi: 10.1073/pnas.1006243107. Epub 2010 Jul 7.

19.

The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency.

Krentz AD, Murphy MW, Kim S, Cook MS, Capel B, Zhu R, Matin A, Sarver AL, Parker KL, Griswold MD, Looijenga LH, Bardwell VJ, Zarkower D.

Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22323-8. doi: 10.1073/pnas.0905431106. Epub 2009 Dec 10.

20.

Role of the transcriptional corepressor Bcor in embryonic stem cell differentiation and early embryonic development.

Wamstad JA, Corcoran CM, Keating AM, Bardwell VJ.

PLoS One. 2008 Jul 30;3(7):e2814. doi: 10.1371/journal.pone.0002814.

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