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Two hydrophobic residues can determine the specificity of mitogen-activated protein kinase docking interactions.

Bardwell AJ, Bardwell L.

J Biol Chem. 2015 Oct 30;290(44):26661-74. doi: 10.1074/jbc.M115.691436.


CK2 activates kinesin via induction of a conformational change.

Mattson-Hoss MK, Niitani Y, Gordon EA, Jun Y, Bardwell L, Tomishige M, Gross SP.

Proc Natl Acad Sci U S A. 2014 May 13;111(19):7000-5. doi: 10.1073/pnas.1321419111.


Combining docking site and phosphosite predictions to find new substrates: identification of smoothelin-like-2 (SMTNL2) as a c-Jun N-terminal kinase (JNK) substrate.

Gordon EA, Whisenant TC, Zeller M, Kaake RM, Gordon WM, Krotee P, Patel V, Huang L, Baldi P, Bardwell L.

Cell Signal. 2013 Dec;25(12):2518-29. doi: 10.1016/j.cellsig.2013.08.004.


Correcting for rater bias in scores on a continuous scale, with application to breast density.

Sperrin M, Bardwell L, Sergeant JC, Astley S, Buchan I.

Stat Med. 2013 Nov 20;32(26):4666-78. doi: 10.1002/sim.5848.


Protein scaffolds can enhance the bistability of multisite phosphorylation systems.

Chan C, Liu X, Wang L, Bardwell L, Nie Q, Enciso G.

PLoS Comput Biol. 2012;8(6):e1002551. doi: 10.1371/journal.pcbi.1002551.


Casein kinase 2 reverses tail-independent inactivation of kinesin-1.

Xu J, Reddy BJ, Anand P, Shu Z, Cermelli S, Mattson MK, Tripathy SK, Hoss MT, James NS, King SJ, Huang L, Bardwell L, Gross SP.

Nat Commun. 2012 Mar 27;3:754. doi: 10.1038/ncomms1760.


Noise filtering tradeoffs in spatial gradient sensing and cell polarization response.

Chou CS, Bardwell L, Nie Q, Yi TM.

BMC Syst Biol. 2011 Dec 13;5:196. doi: 10.1186/1752-0509-5-196.


BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages.

Bernardo AS, Faial T, Gardner L, Niakan KK, Ortmann D, Senner CE, Callery EM, Trotter MW, Hemberger M, Smith JC, Bardwell L, Moffett A, Pedersen RA.

Cell Stem Cell. 2011 Aug 5;9(2):144-55. doi: 10.1016/j.stem.2011.06.015.


Connecting food environments and health through the relational nature of aesthetics: gaining insight through the community gardening experience.

Hale J, Knapp C, Bardwell L, Buchenau M, Marshall J, Sancar F, Litt JS.

Soc Sci Med. 2011 Jun;72(11):1853-63. doi: 10.1016/j.socscimed.2011.03.044.


Plant signalling pathways: a comparative evolutionary overview.

Hetherington AM, Bardwell L.

Curr Biol. 2011 May 10;21(9):R317-9. doi: 10.1016/j.cub.2011.04.013. No abstract available.


Synthetic biology: modulating the MAP kinase module.

Bardwell L.

Curr Biol. 2011 Apr 12;21(7):R249-51. doi: 10.1016/j.cub.2011.02.042.


A scalable and integrative system for pathway bioinformatics and systems biology.

Compani B, Su T, Chang I, Cheng J, Shah KH, Whisenant T, Dou Y, Bergmann A, Cheong R, Wold B, Bardwell L, Levchenko A, Baldi P, Mjolsness E.

Adv Exp Med Biol. 2010;680:523-34. doi: 10.1007/978-1-4419-5913-3_58.


Computational prediction and experimental verification of new MAP kinase docking sites and substrates including Gli transcription factors.

Whisenant TC, Ho DT, Benz RW, Rogers JS, Kaake RM, Gordon EA, Huang L, Baldi P, Bardwell L.

PLoS Comput Biol. 2010 Aug 26;6(8). pii: e1000908. doi: 10.1371/journal.pcbi.1000908.


Ultrasensitive responses and specificity in cell signaling.

Haney S, Bardwell L, Nie Q.

BMC Syst Biol. 2010 Aug 25;4:119. doi: 10.1186/1752-0509-4-119.


A combination of multisite phosphorylation and substrate sequestration produces switchlike responses.

Liu X, Bardwell L, Nie Q.

Biophys J. 2010 Apr 21;98(8):1396-407. doi: 10.1016/j.bpj.2009.12.4307.


Collective efficacy in Denver, Colorado: Strengthening neighborhoods and health through community gardens.

Teig E, Amulya J, Bardwell L, Buchenau M, Marshall JA, Litt JS.

Health Place. 2009 Dec;15(4):1115-22. doi: 10.1016/j.healthplace.2009.06.003.


Selectivity of docking sites in MAPK kinases.

Bardwell AJ, Frankson E, Bardwell L.

J Biol Chem. 2009 May 8;284(19):13165-73. doi: 10.1074/jbc.M900080200.


Oscillatory phosphorylation of yeast Fus3 MAP kinase controls periodic gene expression and morphogenesis.

Hilioti Z, Sabbagh W Jr, Paliwal S, Bergmann A, Goncalves MD, Bardwell L, Levchenko A.

Curr Biol. 2008 Nov 11;18(21):1700-6. doi: 10.1016/j.cub.2008.09.027. Erratum in: Curr Biol. 2008 Dec 9;18(23):1897.


Signal transduction: turning a switch into a rheostat.

Bardwell L.

Curr Biol. 2008 Oct 14;18(19):R910-2. doi: 10.1016/j.cub.2008.07.082.


Mathematical models of specificity in cell signaling.

Bardwell L, Zou X, Nie Q, Komarova NL.

Biophys J. 2007 May 15;92(10):3425-41.

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