Send to

Choose Destination

Toxicity, Benzodiazepine.


StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018-.
2018 Jan 31.

Author information

Riverside Community Hospital/UCRiverside
Riverside Comm Hosp, UC Riverside


Since the 1960s, with the development of chlordiazepoxide (Librium) and soon later diazepam (Valium), benzodiazepines (BZDs) quickly became mainstream medications secondary to their vastly superior safety profiles when compared to previous sedative-hypnotics such as barbiturates and other non-barbiturates used for the treatment of anxiety and insomnia. Since their development, multiple BZD compounds have evolved over the last several decades and are used to treat anxiety, seizures, withdrawal states, insomnia, agitation and are also frequently used for procedural sedation. Due to their many uses and addictive properties, BZDs have been widely prescribed and abused since their development several decades ago. Today, there are over 50 different agents available on the worldwide market and the high incidence of benzodiazepine overdose mirrors their widespread use and availability.

Copyright © 2018, StatPearls Publishing LLC.

Supplemental Content

Loading ...
Support Center