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Best matches for Böhn L[au]:

Crystal structures of agonist-bound human cannabinoid receptor CB<sub>1</sub>. Hua T et al. Nature. (2017)

Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics. Schmid CL et al. Cell. (2017)

Reply. Simrén M et al. Gastroenterology. (2016)

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Items: 1 to 20 of 141


Probing the CB1 Cannabinoid Receptor Binding Pocket with AM6538, a High-Affinity Irreversible Antagonist.

Laprairie RB, Vemuri K, Stahl EL, Korde A, Ho JH, Grim TW, Hua T, Wu Y, Stevens RC, Liu ZJ, Makriyannis A, Bohn LM.

Mol Pharmacol. 2019 Nov;96(5):619-628. doi: 10.1124/mol.119.116483. Epub 2019 Sep 12.


A G protein signaling-biased agonist at the μ-opioid receptor reverses morphine tolerance while preventing morphine withdrawal.

Grim TW, Schmid CL, Stahl EL, Pantouli F, Ho JH, Acevedo-Canabal A, Kennedy NM, Cameron MD, Bannister TD, Bohn LM.

Neuropsychopharmacology. 2019 Aug 23. doi: 10.1038/s41386-019-0491-8. [Epub ahead of print]


Quantitating Ligand Bias Using the Competitive Model of Ligand Activity.

Stahl EL, Ehlert FJ, Bohn LM.

Methods Mol Biol. 2019;1957:235-247. doi: 10.1007/978-1-4939-9158-7_15.


Crystal Structure of the Human Cannabinoid Receptor CB2.

Li X, Hua T, Vemuri K, Ho JH, Wu Y, Wu L, Popov P, Benchama O, Zvonok N, Locke K, Qu L, Han GW, Iyer MR, Cinar R, Coffey NJ, Wang J, Wu M, Katritch V, Zhao S, Kunos G, Bohn LM, Makriyannis A, Stevens RC, Liu ZJ.

Cell. 2019 Jan 24;176(3):459-467.e13. doi: 10.1016/j.cell.2018.12.011. Epub 2019 Jan 10.


Preference for emotionally meaningful activity in Alzheimer's disease.

Bohn L, Kwong See ST, Fung HH.

Aging Ment Health. 2019 Nov;23(11):1578-1585. doi: 10.1080/13607863.2018.1506750. Epub 2018 Dec 27.


Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists.

Tosh DK, Ciancetta A, Mannes P, Warnick E, Janowsky A, Eshleman AJ, Gizewski E, Brust TF, Bohn LM, Auchampach JA, Gao ZG, Jacobson KA.

ACS Omega. 2018 Oct 31;3(10):12658-12678. doi: 10.1021/acsomega.8b01237. Epub 2018 Oct 4.


Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias.

Kennedy NM, Schmid CL, Ross NC, Lovell KM, Yue Z, Chen YT, Cameron MD, Bohn LM, Bannister TD.

J Med Chem. 2018 Oct 11;61(19):8895-8907. doi: 10.1021/acs.jmedchem.8b01136. Epub 2018 Sep 24.


The effect of quinine in two bottle choice procedures in C57BL6 mice: Opioid preference, somatic withdrawal, and pharmacokinetic outcomes.

Grim TW, Park SJ, Schmid CL, Laprairie RB, Cameron M, Bohn LM.

Drug Alcohol Depend. 2018 Oct 1;191:195-202. doi: 10.1016/j.drugalcdep.2018.05.034. Epub 2018 Aug 2.


Arrestin recruitment to dopamine D2 receptor mediates locomotion but not incentive motivation.

Donthamsetti P, Gallo EF, Buck DC, Stahl EL, Zhu Y, Lane JR, Bohn LM, Neve KA, Kellendonk C, Javitch JA.

Mol Psychiatry. 2018 Aug 17. doi: 10.1038/s41380-018-0212-4. [Epub ahead of print]


G protein signaling-biased agonism at the κ-opioid receptor is maintained in striatal neurons.

Ho JH, Stahl EL, Schmid CL, Scarry SM, Aubé J, Bohn LM.

Sci Signal. 2018 Aug 7;11(542). pii: eaar4309. doi: 10.1126/scisignal.aar4309.


Neither self-reported atopy nor IgE-mediated allergy are linked to gastrointestinal symptoms in patients with irritable bowel syndrome.

Nybacka S, Öhman L, Störsrud S, Mybeck M, Böhn L, Wilpart K, Winkvist A, Bengtsson U, Törnblom H, Simrén M.

Neurogastroenterol Motil. 2018 Oct;30(10):e13379. doi: 10.1111/nmo.13379. Epub 2018 Jun 1.


Physical Activity is Inversely Associated With Arterial Stiffness in Adult Males: A Brief Communication.

Cavalcante SL, Bohn L, Ribeiro F, Oliveira J.

Heart Lung Circ. 2019 Apr;28(4):e29-e32. doi: 10.1016/j.hlc.2018.02.009. Epub 2018 Feb 21. No abstract available.


O6C-20-nor-salvinorin A is a stable and potent KOR agonist.

Hirasawa S, Cho M, Brust TF, Roach JJ, Bohn LM, Shenvi RA.

Bioorg Med Chem Lett. 2018 Sep 1;28(16):2770-2772. doi: 10.1016/j.bmcl.2018.01.055. Epub 2018 Jan 31.


The neonatal anti-viral response fails to control measles virus spread in neurons despite interferon-gamma expression and a Th1-like cytokine profile.

Ganesan P, Chandwani MN, Creisher PS, Bohn L, O'Donnell LA.

J Neuroimmunol. 2018 Mar 15;316:80-97. doi: 10.1016/j.jneuroim.2017.12.018. Epub 2017 Dec 28.


Dynamic Strategic Bond Analysis Yields a Ten-Step Synthesis of 20-nor-Salvinorin A, a Potent κ-OR Agonist.

Roach JJ, Sasano Y, Schmid CL, Zaidi S, Katritch V, Stevens RC, Bohn LM, Shenvi RA.

ACS Cent Sci. 2017 Dec 27;3(12):1329-1336. doi: 10.1021/acscentsci.7b00488. Epub 2017 Dec 13.


Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics.

Schmid CL, Kennedy NM, Ross NC, Lovell KM, Yue Z, Morgenweck J, Cameron MD, Bannister TD, Bohn LM.

Cell. 2017 Nov 16;171(5):1165-1175.e13. doi: 10.1016/j.cell.2017.10.035.


Divergence of developmental trajectories is triggered interactively by early social and ecological experience in a cooperative breeder.

Fischer S, Bohn L, Oberhummer E, Nyman C, Taborsky B.

Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9300-E9307. doi: 10.1073/pnas.1705934114. Epub 2017 Oct 6.


Approaches to Assess Biased Signaling at the CB1R Receptor.

Laprairie RB, Stahl EL, Bohn LM.

Methods Enzymol. 2017;593:259-279. doi: 10.1016/bs.mie.2017.06.031. Epub 2017 Jul 5.


Seeking (and Finding) Biased Ligands of the Kappa Opioid Receptor.

Bohn LM, Aubé J.

ACS Med Chem Lett. 2017 Jul 5;8(7):694-700. doi: 10.1021/acsmedchemlett.7b00224. eCollection 2017 Jul 13.


Crystal structures of agonist-bound human cannabinoid receptor CB1.

Hua T, Vemuri K, Nikas SP, Laprairie RB, Wu Y, Qu L, Pu M, Korde A, Jiang S, Ho JH, Han GW, Ding K, Li X, Liu H, Hanson MA, Zhao S, Bohn LM, Makriyannis A, Stevens RC, Liu ZJ.

Nature. 2017 Jul 27;547(7664):468-471. doi: 10.1038/nature23272. Epub 2017 Jul 5.

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