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Items: 10


Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion.

Chopra M, Biehl M, Steinfatt T, Brandl A, Kums J, Amich J, Vaeth M, Kuen J, Holtappels R, Podlech J, Mottok A, Kraus S, Jordán-Garrote AL, Bäuerlein CA, Brede C, Ribechini E, Fick A, Seher A, Polz J, Ottmüller KJ, Baker J, Nishikii H, Ritz M, Mattenheimer K, Schwinn S, Winter T, Schäfer V, Krappmann S, Einsele H, Müller TD, Reddehase MJ, Lutz MB, Männel DN, Berberich-Siebelt F, Wajant H, Beilhack A.

J Exp Med. 2016 Aug 22;213(9):1881-900. doi: 10.1084/jem.20151563. Epub 2016 Aug 15.


The Zebrafish Breathes New Life into the Study of Tuberculosis.

Myllymäki H, Bäuerlein CA, Rämet M.

Front Immunol. 2016 May 19;7:196. doi: 10.3389/fimmu.2016.00196. eCollection 2016. Review.


Inactivation of ca10a and ca10b Genes Leads to Abnormal Embryonic Development and Alters Movement Pattern in Zebrafish.

Aspatwar A, Tolvanen ME, Ojanen MJ, Barker HR, Saralahti AK, Bäuerlein CA, Ortutay C, Pan P, Kuuslahti M, Parikka M, Rämet M, Parkkila S.

PLoS One. 2015 Jul 28;10(7):e0134263. doi: 10.1371/journal.pone.0134263. eCollection 2015.


Blocking TWEAK-Fn14 interaction inhibits hematopoietic stem cell transplantation-induced intestinal cell death and reduces GVHD.

Chopra M, Brandl A, Siegmund D, Mottok A, Schäfer V, Biehl M, Kraus S, Bäuerlein CA, Ritz M, Mattenheimer K, Schwinn S, Seher A, Grabinger T, Einsele H, Rosenwald A, Brunner T, Beilhack A, Wajant H.

Blood. 2015 Jul 23;126(4):437-44. doi: 10.1182/blood-2015-01-620583. Epub 2015 May 26.


Selective NFAT targeting in T cells ameliorates GvHD while maintaining antitumor activity.

Vaeth M, Bäuerlein CA, Pusch T, Findeis J, Chopra M, Mottok A, Rosenwald A, Beilhack A, Berberich-Siebelt F.

Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):1125-30. doi: 10.1073/pnas.1409290112. Epub 2015 Jan 12.


Tumor necrosis factor induces tumor promoting and anti-tumoral effects on pancreatic cancer via TNFR1.

Chopra M, Lang I, Salzmann S, Pachel C, Kraus S, Bäuerlein CA, Brede C, Garrote AL, Mattenheimer K, Ritz M, Schwinn S, Graf C, Schäfer V, Frantz S, Einsele H, Wajant H, Beilhack A.

PLoS One. 2013 Sep 30;8(9):e75737. doi: 10.1371/journal.pone.0075737. eCollection 2013.


A diagnostic window for the treatment of acute graft-versus-host disease prior to visible clinical symptoms in a murine model.

Bäuerlein CA, Riedel SS, Baker J, Brede C, Garrote AL, Chopra M, Ritz M, Beilhack GF, Schulz S, Zeiser R, Schlegel PG, Einsele H, Negrin RS, Beilhack A.

BMC Med. 2013 May 21;11:134. doi: 10.1186/1741-7015-11-134.


Tumor necrosis factor receptor 2-dependent homeostasis of regulatory T cells as a player in TNF-induced experimental metastasis.

Chopra M, Riedel SS, Biehl M, Krieger S, von Krosigk V, Bäuerlein CA, Brede C, Jordan Garrote AL, Kraus S, Schäfer V, Ritz M, Mattenheimer K, Degla A, Mottok A, Einsele H, Wajant H, Beilhack A.

Carcinogenesis. 2013 Jun;34(6):1296-303. doi: 10.1093/carcin/bgt038. Epub 2013 Feb 5.


Non-invasive imaging provides spatiotemporal information on disease progression and response to therapy in a murine model of multiple myeloma.

Riedel SS, Mottok A, Brede C, Bäuerlein CA, Jordán Garrote AL, Ritz M, Mattenheimer K, Rosenwald A, Einsele H, Bogen B, Beilhack A.

PLoS One. 2012;7(12):e52398. doi: 10.1371/journal.pone.0052398. Epub 2012 Dec 26.


Mapping immune processes in intact tissues at cellular resolution.

Brede C, Friedrich M, Jordán-Garrote AL, Riedel SS, Bäuerlein CA, Heinze KG, Bopp T, Schulz S, Mottok A, Kiesel C, Mattenheimer K, Ritz M, von Krosigk V, Rosenwald A, Einsele H, Negrin RS, Harms GS, Beilhack A.

J Clin Invest. 2012 Dec;122(12):4439-46. doi: 10.1172/JCI65100. Epub 2012 Nov 12.

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