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Items: 1 to 20 of 129

1.

The Conformational Flexibility of the Acyltransferase from the Disorazole Polyketide Synthase Is Revealed by an X-ray Free-Electron Laser Using a Room-Temperature Sample Delivery Method for Serial Crystallography.

Mathews II, Allison K, Robbins T, Lyubimov AY, Uervirojnangkoorn M, Brunger AT, Khosla C, DeMirci H, McPhillips SE, Hollenbeck M, Soltis M, Cohen AE.

Biochemistry. 2017 Sep 12;56(36):4751-4756. doi: 10.1021/acs.biochem.7b00711. Epub 2017 Aug 31.

2.

The primed SNARE-complexin-synaptotagmin complex for neuronal exocytosis.

Zhou Q, Zhou P, Wang AL, Wu D, Zhao M, Südhof TC, Brunger AT.

Nature. 2017 Aug 24;548(7668):420-425. doi: 10.1038/nature23484. Epub 2017 Aug 16.

3.

Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18.

Lai Y, Choi UB, Leitz J, Rhee HJ, Lee C, Altas B, Zhao M, Pfuetzner RA, Wang AL, Brose N, Rhee J, Brunger AT.

Neuron. 2017 Aug 2;95(3):591-607.e10. doi: 10.1016/j.neuron.2017.07.004.

4.

Morphologies of synaptic protein membrane fusion interfaces.

Gipson P, Fukuda Y, Danev R, Lai Y, Chen DH, Baumeister W, Brunger AT.

Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9110-9115. doi: 10.1073/pnas.1708492114. Epub 2017 Jul 24.

5.

Conformational change of syntaxin linker region induced by Munc13s initiates SNARE complex formation in synaptic exocytosis.

Wang S, Choi UB, Gong J, Yang X, Li Y, Wang AL, Yang X, Brunger AT, Ma C.

EMBO J. 2017 Mar 15;36(6):816-829. doi: 10.15252/embj.201695775. Epub 2017 Jan 30.

PMID:
28137749
6.

Structure of photosystem II and substrate binding at room temperature.

Young ID, Ibrahim M, Chatterjee R, Gul S, Fuller F, Koroidov S, Brewster AS, Tran R, Alonso-Mori R, Kroll T, Michels-Clark T, Laksmono H, Sierra RG, Stan CA, Hussein R, Zhang M, Douthit L, Kubin M, de Lichtenberg C, Long Vo P, Nilsson H, Cheah MH, Shevela D, Saracini C, Bean MA, Seuffert I, Sokaras D, Weng TC, Pastor E, Weninger C, Fransson T, Lassalle L, Bräuer P, Aller P, Docker PT, Andi B, Orville AM, Glownia JM, Nelson S, Sikorski M, Zhu D, Hunter MS, Lane TJ, Aquila A, Koglin JE, Robinson J, Liang M, Boutet S, Lyubimov AY, Uervirojnangkoorn M, Moriarty NW, Liebschner D, Afonine PV, Waterman DG, Evans G, Wernet P, Dobbek H, Weis WI, Brunger AT, Zwart PH, Adams PD, Zouni A, Messinger J, Bergmann U, Sauter NK, Kern J, Yachandra VK, Yano J.

Nature. 2016 Dec 15;540(7633):453-457. doi: 10.1038/nature20161. Epub 2016 Nov 21.

7.

C-terminal domain of mammalian complexin-1 localizes to highly curved membranes.

Gong J, Lai Y, Li X, Wang M, Leitz J, Hu Y, Zhang Y, Choi UB, Cipriano D, Pfuetzner RA, Südhof TC, Yang X, Brunger AT, Diao J.

Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7590-E7599. Epub 2016 Nov 7.

8.

Advances in X-ray free electron laser (XFEL) diffraction data processing applied to the crystal structure of the synaptotagmin-1 / SNARE complex.

Lyubimov AY, Uervirojnangkoorn M, Zeldin OB, Zhou Q, Zhao M, Brewster AS, Michels-Clark T, Holton JM, Sauter NK, Weis WI, Brunger AT.

Elife. 2016 Oct 12;5. pii: e18740. doi: 10.7554/eLife.18740.

9.

De novo phasing with X-ray laser reveals mosquito larvicide BinAB structure.

Colletier JP, Sawaya MR, Gingery M, Rodriguez JA, Cascio D, Brewster AS, Michels-Clark T, Hice RH, Coquelle N, Boutet S, Williams GJ, Messerschmidt M, DePonte DP, Sierra RG, Laksmono H, Koglin JE, Hunter MS, Park HW, Uervirojnangkoorn M, Bideshi DK, Brunger AT, Federici BA, Sauter NK, Eisenberg DS.

Nature. 2016 Nov 3;539(7627):43-47. doi: 10.1038/nature19825. Epub 2016 Sep 28.

10.

Expression of C1ql3 in Discrete Neuronal Populations Controls Efferent Synapse Numbers and Diverse Behaviors.

Martinelli DC, Chew KS, Rohlmann A, Lum MY, Ressl S, Hattar S, Brunger AT, Missler M, Südhof TC.

Neuron. 2016 Sep 7;91(5):1034-1051. doi: 10.1016/j.neuron.2016.07.002. Epub 2016 Jul 28.

11.

N-terminal domain of complexin independently activates calcium-triggered fusion.

Lai Y, Choi UB, Zhang Y, Zhao M, Pfuetzner RA, Wang AL, Diao J, Brunger AT.

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):E4698-707. doi: 10.1073/pnas.1604348113. Epub 2016 Jul 21.

12.

Phosphorylation of residues inside the SNARE complex suppresses secretory vesicle fusion.

Malmersjö S, Di Palma S, Diao J, Lai Y, Pfuetzner RA, Wang AL, McMahon MA, Hayer A, Porteus M, Bodenmiller B, Brunger AT, Meyer T.

EMBO J. 2016 Aug 15;35(16):1810-21. doi: 10.15252/embj.201694071. Epub 2016 Jul 11.

13.

IOTA: integration optimization, triage and analysis tool for the processing of XFEL diffraction images.

Lyubimov AY, Uervirojnangkoorn M, Zeldin OB, Brewster AS, Murray TD, Sauter NK, Berger JM, Weis WI, Brunger AT.

J Appl Crystallogr. 2016 May 11;49(Pt 3):1057-1064. eCollection 2016 Jun 1.

14.

Complexin induces a conformational change at the membrane-proximal C-terminal end of the SNARE complex.

Choi UB, Zhao M, Zhang Y, Lai Y, Brunger AT.

Elife. 2016 Jun 2;5. pii: e16886. doi: 10.7554/eLife.16886.

15.

Simultaneous single-molecule epigenetic imaging of DNA methylation and hydroxymethylation.

Song CX, Diao J, Brunger AT, Quake SR.

Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4338-43. doi: 10.1073/pnas.1600223113. Epub 2016 Mar 28.

16.

Atomic resolution experimental phase information reveals extensive disorder and bound 2-methyl-2,4-pentanediol in Ca(2+)-calmodulin.

Lin J, van den Bedem H, Brunger AT, Wilson MA.

Acta Crystallogr D Struct Biol. 2016 Jan;72(Pt 1):83-92. doi: 10.1107/S2059798315021609. Epub 2016 Jan 1.

17.

High-density grids for efficient data collection from multiple crystals.

Baxter EL, Aguila L, Alonso-Mori R, Barnes CO, Bonagura CA, Brehmer W, Brunger AT, Calero G, Caradoc-Davies TT, Chatterjee R, Degrado WF, Fraser JS, Ibrahim M, Kern J, Kobilka BK, Kruse AC, Larsson KM, Lemke HT, Lyubimov AY, Manglik A, McPhillips SE, Norgren E, Pang SS, Soltis SM, Song J, Thomaston J, Tsai Y, Weis WI, Woldeyes RA, Yachandra V, Yano J, Zouni A, Cohen AE.

Acta Crystallogr D Struct Biol. 2016 Jan;72(Pt 1):2-11. doi: 10.1107/S2059798315020847. Epub 2016 Jan 1.

18.

Recent Advances in Deciphering the Structure and Molecular Mechanism of the AAA+ ATPase N-Ethylmaleimide-Sensitive Factor (NSF).

Zhao M, Brunger AT.

J Mol Biol. 2016 May 8;428(9 Pt B):1912-26. doi: 10.1016/j.jmb.2015.10.026. Epub 2015 Nov 3. Review.

19.

Correction: Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion.

Diao J, Grob P, Cipriano DJ, Kyoung M, Zhang Y, Shah S, Nguyen A, Padolina M, Srivastava A, Vrljic M, Shah A, Nogales E, Chu S, Brunger AT.

Elife. 2015 Oct 21;4:e12289. doi: 10.7554/eLife.12289. No abstract available.

20.

A high-transparency, micro-patternable chip for X-ray diffraction analysis of microcrystals under native growth conditions.

Murray TD, Lyubimov AY, Ogata CM, Vo H, Uervirojnangkoorn M, Brunger AT, Berger JM.

Acta Crystallogr D Biol Crystallogr. 2015 Oct;71(Pt 10):1987-97. doi: 10.1107/S1399004715015011. Epub 2015 Sep 26.

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