Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 123


Sialidase down-regulation reduces non-HDL cholesterol, inhibits leukocyte transmigration and attenuates atherosclerosis in ApoE knockout mice.

White EJ, Gyulay G, Lhoták Š, Szewczyk MM, Chong T, Fuller MT, Dadoo O, Fox-Robichaud AE, Austin RC, Trigatti B, Igdoura SA.

J Biol Chem. 2018 Aug 10. pii: jbc.RA118.004589. doi: 10.1074/jbc.RA118.004589. [Epub ahead of print]


MAPping the kinase landscape of macrophage activation.

Platko K, Lebeau P, Austin RC.

J Biol Chem. 2018 Jun 22;293(25):9910-9911. doi: 10.1074/jbc.H118.003380.


Thrombotic characteristics of extracellular vesicles derived from prostate cancer cells.

Al Saleh HA, Haas-Neill S, Al-Hashimi A, Kapoor A, Shayegan B, Austin RC, Al-Nedawi K.

Prostate. 2018 Sep;78(13):953-961. doi: 10.1002/pros.23653. Epub 2018 May 15.


Pharmacologic inhibition of S1P attenuates ATF6 expression, causes ER stress and contributes to apoptotic cell death.

Lebeau P, Byun JH, Yousof T, Austin RC.

Toxicol Appl Pharmacol. 2018 Jun 15;349:1-7. doi: 10.1016/j.taap.2018.04.020. Epub 2018 Apr 22.


Endoplasmic Reticulum Chaperone GRP78 Protects Heart From Ischemia/Reperfusion Injury Through Akt Activation.

Bi X, Zhang G, Wang X, Nguyen C, May HI, Li X, Al-Hashimi AA, Austin RC, Gillette TG, Fu G, Wang ZV, Hill JA.

Circ Res. 2018 May 25;122(11):1545-1554. doi: 10.1161/CIRCRESAHA.117.312641. Epub 2018 Apr 18.


Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained.

Lebeau P, Platko K, Al-Hashimi AA, Byun JH, Lhoták Š, Holzapfel N, Gyulay G, Igdoura SA, Cool DR, Trigatti B, Seidah NG, Austin RC.

J Biol Chem. 2018 May 11;293(19):7329-7343. doi: 10.1074/jbc.RA117.001049. Epub 2018 Mar 28.


Using cadaveric simulation to introduce the concept and skills required to start performing transanal total mesorectal excision.

Wynn GR, Austin RCT, Motson RW.

Colorectal Dis. 2018 Jun;20(6):496-501. doi: 10.1111/codi.14034.


Separate roles of IL-6 and oncostatin M in mouse macrophage polarization in vitro and in vivo.

Dubey A, Izakelian L, Ayaub EA, Ho L, Stephenson K, Wong S, Kwofie K, Austin RC, Botelho F, Ask K, Richards CD.

Immunol Cell Biol. 2018 Mar;96(3):257-272. doi: 10.1111/imcb.1035. Epub 2017 Dec 26.


Rosuvastatin Reduces Aortic Sinus and Coronary Artery Atherosclerosis in SR-B1 (Scavenger Receptor Class B Type 1)/ApoE (Apolipoprotein E) Double Knockout Mice Independently of Plasma Cholesterol Lowering.

Yu P, Xiong T, Tenedero CB, Lebeau P, Ni R, MacDonald ME, Gross PL, Austin RC, Trigatti BL.

Arterioscler Thromb Vasc Biol. 2018 Jan;38(1):26-39. doi: 10.1161/ATVBAHA.117.305140. Epub 2017 Nov 21.


The Pleckstrin homology like domain family member, TDAG51, is temporally regulated during skeletal muscle regeneration.

Coleman SK, Cao AW, Rebalka IA, Gyulay G, Chambers PJ, Tupling AR, Austin RC, Hawke TJ.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):499-505. doi: 10.1016/j.bbrc.2017.11.019. Epub 2017 Nov 8.


Autoantibodies against the cell surface-associated chaperone GRP78 stimulate tumor growth via tissue factor.

Al-Hashimi AA, Lebeau P, Majeed F, Polena E, Lhotak Š, Collins CAF, Pinthus JH, Gonzalez-Gronow M, Hoogenes J, Pizzo SV, Crowther M, Kapoor A, Rak J, Gyulay G, D'Angelo S, Marchiò S, Pasqualini R, Arap W, Shayegan B, Austin RC.

J Biol Chem. 2017 Dec 22;292(51):21180-21192. doi: 10.1074/jbc.M117.799908. Epub 2017 Oct 24.


Endoplasmic reticulum protein ERp46 in prostate adenocarcinoma.

Duivenvoorden WCM, Hopmans SN, Austin RC, Pinthus JH.

Oncol Lett. 2017 May;13(5):3624-3630. doi: 10.3892/ol.2017.5908. Epub 2017 Mar 24.


Endoplasmic Reticulum Stress and Ca2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism.

Lebeau P, Al-Hashimi A, Sood S, Lhoták Š, Yu P, Gyulay G, Paré G, Chen SR, Trigatti B, Prat A, Seidah NG, Austin RC.

J Biol Chem. 2017 Jan 27;292(4):1510-1523. doi: 10.1074/jbc.M116.744235. Epub 2016 Dec 1.


Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis.

Pinkosky SL, Newton RS, Day EA, Ford RJ, Lhotak S, Austin RC, Birch CM, Smith BK, Filippov S, Groot PH, Steinberg GR, Lalwani ND.

Nat Commun. 2016 Nov 28;7:13457. doi: 10.1038/ncomms13457.


Characterization of Proliferating Lesion-Resident Cells During All Stages of Atherosclerotic Growth.

Lhoták Š, Gyulay G, Cutz JC, Al-Hashimi A, Trigatti BL, Richards CD, Igdoura SA, Steinberg GR, Bramson J, Ask K, Austin RC.

J Am Heart Assoc. 2016 Aug 15;5(8). pii: e003945. doi: 10.1161/JAHA.116.003945.


GRP78 and CHOP modulate macrophage apoptosis and the development of bleomycin-induced pulmonary fibrosis.

Ayaub EA, Kolb PS, Mohammed-Ali Z, Tat V, Murphy J, Bellaye PS, Shimbori C, Boivin FJ, Lai R, Lynn EG, Lhoták Š, Bridgewater D, Kolb MR, Inman MD, Dickhout JG, Austin RC, Ask K.

J Pathol. 2016 Aug;239(4):411-25. doi: 10.1002/path.4738. Epub 2016 Jun 7.


Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores.

Al-Hashimi AA, Caldwell J, Gonzalez-Gronow M, Pizzo SV, Aboumrad D, Pozza L, Al-Bayati H, Weitz JI, Stafford A, Chan H, Kapoor A, Jacobsen DW, Dickhout JG, Austin RC.

J Biol Chem. 2015 Nov 27;290(48):28725. doi: 10.1074/jbc.A110.119107. No abstract available.


Salicylate improves macrophage cholesterol homeostasis via activation of Ampk.

Fullerton MD, Ford RJ, McGregor CP, LeBlond ND, Snider SA, Stypa SA, Day EA, Lhoták Š, Schertzer JD, Austin RC, Kemp BE, Steinberg GR.

J Lipid Res. 2015 May;56(5):1025-33. doi: 10.1194/jlr.M058875. Epub 2015 Mar 15.


Endoplasmic reticulum protein ERp46 in renal cell carcinoma.

Duivenvoorden WC, Paschos A, Hopmans SN, Austin RC, Pinthus JH.

PLoS One. 2014 Mar 3;9(3):e90389. doi: 10.1371/journal.pone.0090389. eCollection 2014.


Underactivation of the adiponectin-adiponectin receptor 1 axis in clear cell renal cell carcinoma: implications for progression.

Kleinmann N, Duivenvoorden WC, Hopmans SN, Beatty LK, Qiao S, Gallino D, Lhotak S, Daya D, Paschos A, Austin RC, Pinthus JH.

Clin Exp Metastasis. 2014 Feb;31(2):169-83. doi: 10.1007/s10585-013-9618-1. Epub 2013 Oct 5.


Supplemental Content

Loading ...
Support Center