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Best matches for Aurora A:

Aurora kinase A inhibitors: promising agents in antitumoral therapy. Malumbres M et al. Expert Opin Ther Targets. (2014)

Aurora-A: a potential DNA repair modulator. Wang Y et al. Tumour Biol. (2014)

Synergism between inhibitors of Aurora A and KIF11 overcomes KIF15-dependent drug resistance. Ma HT et al. Mol Oncol. (2014)

Search results

Items: 1 to 20 of 2069

1.

An old story in the parallel synthesis world: an approach to hydantoin libraries.

Bogolubsky A, Moroz YS, Savych O, Pipko S, Konovets A, Platonov MO, Vasylchenko OV, Hurmach VV, Grygorenko OO.

ACS Comb Sci. 2017 Dec 11. doi: 10.1021/acscombsci.7b00163. [Epub ahead of print]

PMID:
29227678
2.

p37/UBXN2B regulates spindle orientation by limiting cortical NuMA recruitment via PP1/Repo-Man.

Lee BH, Schwager F, Meraldi P, Gotta M.

J Cell Biol. 2017 Dec 8. pii: jcb.201707050. doi: 10.1083/jcb.201707050. [Epub ahead of print]

PMID:
29222185
3.

Molecular targeting of the Aurora-A/SMAD5 oncogenic axis restores chemosensitivity in human breast cancer cells.

Opyrchal M, Gil M, Salisbury JL, Goetz MP, Suman V, Degnim A, McCubrey J, Haddad T, Iankov I, Kurokawa CB, Shumacher N, Ingle JN, Galanis E, D'Assoro AB.

Oncotarget. 2017 Sep 1;8(53):91803-91816. doi: 10.18632/oncotarget.20610. eCollection 2017 Oct 31.

4.

Aurora kinase A as a possible marker for endocrine resistance in early estrogen receptor positive breast cancer.

Lykkesfeldt AE, Iversen BR, Jensen MB, Ejlertsen B, Giobbie-Hurder A, Reiter BE, Kirkegaard T, Rasmussen BB.

Acta Oncol. 2017 Dec 4:1-7. doi: 10.1080/0284186X.2017.1404126. [Epub ahead of print]

PMID:
29202611
5.

Identification of Novel Aurora Kinase A (AURKA) Inhibitors via Hierarchical Ligand-Based Virtual Screening.

Kong Y, Bender A, Yan A.

J Chem Inf Model. 2017 Dec 4. doi: 10.1021/acs.jcim.7b00300. [Epub ahead of print]

PMID:
29202231
6.

Preclinical evaluation of the Aurora kinase inhibitors AMG 900, AZD1152-HQPA, and MK-5108 on SW-872 and 93T449 human liposarcoma cells.

Noronha S, Alt LAC, Scimeca TE, Zarou O, Obrzut J, Zanotti B, Hayward EA, Pillai A, Mathur S, Rojas J, Salamah R, Chandar N, Fay MJ.

In Vitro Cell Dev Biol Anim. 2017 Dec 1. doi: 10.1007/s11626-017-0208-4. [Epub ahead of print]

PMID:
29197031
7.

Aurora A kinase phosphorylates Hec1 to regulate metaphase kinetochore-microtubule dynamics.

DeLuca KF, Meppelink A, Broad AJ, Mick JE, Peersen OB, Pektas S, Lens SMA, DeLuca JG.

J Cell Biol. 2017 Nov 29. pii: jcb.201707160. doi: 10.1083/jcb.201707160. [Epub ahead of print]

PMID:
29187526
8.

A mitosis-specific and R loop-driven ATR pathway promotes faithful chromosome segregation.

Kabeche L, Nguyen HD, Buisson R, Zou L.

Science. 2017 Nov 23. pii: eaan6490. doi: 10.1126/science.aan6490. [Epub ahead of print]

PMID:
29170278
9.

Aurora kinase A inhibitor TCS7010 demonstrates pro-apoptotic effect through the unfolded protein response pathway in HCT116 colon cancer cells.

Lee DH, Kim CG, Lim Y, Shin SY.

Oncol Lett. 2017 Dec;14(6):6571-6577. doi: 10.3892/ol.2017.7023. Epub 2017 Sep 22.

10.

Functional T cells targeting tumor-associated antigens are predictive for recurrence-free survival of patients with radically operated non-small cell lung cancer.

Safi S, Yamauchi Y, Rathinasamy A, Stamova S, Eichhorn M, Warth A, Rauch G, Dienemann H, Hoffmann H, Beckhove P.

Oncoimmunology. 2017 Sep 8;6(11):e1360458. doi: 10.1080/2162402X.2017.1360458. eCollection 2017.

PMID:
29147626
11.

The Effect of Aurora Kinase Inhibitor on Adhesion and Migration in Human Breast Cancer Cells and Clinical Implications.

Zhao H, Owen S, Davies EL, Jiang WG, Martin TA.

World J Oncol. 2017 Oct;8(5):151-161. doi: 10.14740/wjon1062w. Epub 2017 Nov 5.

12.

A novel interaction between kinase activities in regulation of cilia formation.

DeVaul N, Koloustroubis K, Wang R, Sperry AO.

BMC Cell Biol. 2017 Nov 15;18(1):33. doi: 10.1186/s12860-017-0149-5.

13.

A PEGylated platelet free plasma hydrogel based composite scaffold enables stable vascularization and targeted cell delivery for volumetric muscle loss.

Aurora A, Wrice N, Walters TJ, Christy RJ, Natesan S.

Acta Biomater. 2018 Jan;65:150-162. doi: 10.1016/j.actbio.2017.11.019. Epub 2017 Nov 8.

PMID:
29128541
14.

AGBL2 promotes cancer cell growth through IRGM-regulated autophagy and enhanced Aurora A activity in hepatocellular carcinoma.

Wang LL, Jin XH, Cai MY, Li HG, Chen JW, Wang FW, Wang CY, Hu WW, Liu F, Xie D.

Cancer Lett. 2017 Nov 8;414:71-80. doi: 10.1016/j.canlet.2017.11.003. [Epub ahead of print]

PMID:
29126912
15.

Aurora A Functional Single Nucleotide Polymorphism (SNP) Correlates With Clinical Outcome in Patients With Advanced Solid Tumors Treated With Alisertib, an Investigational Aurora A Kinase Inhibitor.

Niu H, Shin H, Gao F, Zhang J, Bahamon B, Danaee H, Melichar B, Schilder RJ, Coleman RL, Falchook G, Adenis A, Behbakht K, DeMichele A, Dees EC, Perez K, Matulonis U, Sawrycki P, Huebner D, Ecsedy J.

EBioMedicine. 2017 Nov;25:50-57. doi: 10.1016/j.ebiom.2017.10.015. Epub 2017 Oct 16.

16.

Design, synthesis and biological activity of N<sup>4</sup>-phenylsubstituted-7H-pyrrolo[2,3-d]pyrimidin-4-amines as dual inhibitors of aurora kinase A and epidermal growth factor receptor kinase.

Kurup S, McAllister B, Liskova P, Mistry T, Fanizza A, Stanford D, Slawska J, Keller U, Hoellein A.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):74-84. doi: 10.1080/14756366.2017.1376666.

PMID:
29115879
17.

The Translation of Cyclin B1 and B2 is Differentially Regulated during Mouse Oocyte Reentry into the Meiotic Cell Cycle.

Han SJ, Martins JPS, Yang Y, Kang MK, Daldello EM, Conti M.

Sci Rep. 2017 Oct 26;7(1):14077. doi: 10.1038/s41598-017-13688-3.

18.

Aurora A activation in mitosis promoted by BuGZ.

Huang Y, Li T, Ems-McClung SC, Walczak CE, Prigent C, Zhu X, Zhang X, Zheng Y.

J Cell Biol. 2017 Oct 26. pii: jcb.201706103. doi: 10.1083/jcb.201706103. [Epub ahead of print]

PMID:
29074706
19.

Chemical Space: Big Data Challenge for Molecular Diversity.

Awale M, Visini R, Probst D, ArĂºs-Pous J, Reymond JL.

Chimia (Aarau). 2017 Oct 25;71(10):661-666. doi: 10.2533/chimia.2017.661.

PMID:
29070411
20.

Critical risk-benefit assessment of the novel anti-cancer aurora a kinase inhibitor alisertib (MLN8237): A comprehensive review of the clinical data.

Tayyar Y, Jubair L, Fallaha S, McMillan NAJ.

Crit Rev Oncol Hematol. 2017 Nov;119:59-65. doi: 10.1016/j.critrevonc.2017.09.006. Epub 2017 Sep 18. Review.

PMID:
29065986

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