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Items: 1 to 20 of 53

1.

Demonstrating the protective efficacy of the novel fluoroquinolone finafloxacin against an inhalational exposure to Burkholderia pseudomallei.

Barnes KB, Hamblin KA, Richards MI, Laws TR, Vente A, Atkins HS, Harding SV.

Antimicrob Agents Chemother. 2017 Apr 24. pii: AAC.00082-17. doi: 10.1128/AAC.00082-17. [Epub ahead of print]

2.

Inhaled Liposomal Ciprofloxacin Protects against a Lethal Infection in a Murine Model of Pneumonic Plague.

Hamblin KA, Armstrong SJ, Barnes KB, Davies C, Laws T, Blanchard JD, Harding SV, Atkins HS.

Front Microbiol. 2017 Feb 6;8:91. doi: 10.3389/fmicb.2017.00091. eCollection 2017.

3.
4.

A Bioluminescent Francisella tularensis SCHU S4 Strain Enables Noninvasive Tracking of Bacterial Dissemination and the Evaluation of Antibiotics in an Inhalational Mouse Model of Tularemia.

Hall CA, Flick-Smith HC, Harding SV, Atkins HS, Titball RW.

Antimicrob Agents Chemother. 2016 Nov 21;60(12):7206-7215. Print 2016 Dec.

5.

Bacillus anthracis TIR Domain-Containing Protein Localises to Cellular Microtubule Structures and Induces Autophagy.

Carlsson E, Thwaite JE, Jenner DC, Spear AM, Flick-Smith H, Atkins HS, Byrne B, Ding JL.

PLoS One. 2016 Jul 8;11(7):e0158575. doi: 10.1371/journal.pone.0158575. eCollection 2016.

6.

Intracellular replication of the well-armed pathogen Burkholderia pseudomallei.

Willcocks SJ, Denman CC, Atkins HS, Wren BW.

Curr Opin Microbiol. 2016 Feb;29:94-103. doi: 10.1016/j.mib.2015.11.007. Epub 2016 Jan 22. Review.

7.

Characterization of New Virulence Factors Involved in the Intracellular Growth and Survival of Burkholderia pseudomallei.

Moule MG, Spink N, Willcocks S, Lim J, Guerra-Assunção JA, Cia F, Champion OL, Senior NJ, Atkins HS, Clark T, Bancroft GJ, Cuccui J, Wren BW.

Infect Immun. 2015 Dec 28;84(3):701-10. doi: 10.1128/IAI.01102-15.

8.

Burkholderia pseudomallei kynB plays a role in AQ production, biofilm formation, bacterial swarming and persistence.

Butt A, Halliday N, Williams P, Atkins HS, Bancroft GJ, Titball RW.

Res Microbiol. 2016 Apr;167(3):159-67. doi: 10.1016/j.resmic.2015.11.002. Epub 2015 Nov 30.

PMID:
26654915
9.

The potential of liposome-encapsulated ciprofloxacin as a tularemia therapy.

Hamblin KA, Wong JP, Blanchard JD, Atkins HS.

Front Cell Infect Microbiol. 2014 Jun 18;4:79. doi: 10.3389/fcimb.2014.00079. eCollection 2014. Review.

10.

Liposome encapsulation of ciprofloxacin improves protection against highly virulent Francisella tularensis strain Schu S4.

Hamblin KA, Armstrong SJ, Barnes KB, Davies C, Wong JP, Blanchard JD, Harding SV, Simpson AJ, Atkins HS.

Antimicrob Agents Chemother. 2014 Jun;58(6):3053-9. doi: 10.1128/AAC.02555-13. Epub 2014 Mar 17.

11.

CpG oligonucleotides protect against Venezuelan equine encephalitis virus infection in a route-dependent manner.

Rees DG, Phillpotts RJ, Griffin KF, Lukaszewski RA, Laws TR, Atkins HS, Krieg AM, Titball RW.

Int J Antimicrob Agents. 2013 Dec;42(6):587-8. doi: 10.1016/j.ijantimicag.2013.09.001. Epub 2013 Oct 1. No abstract available.

PMID:
24210643
12.

The ability of CpG oligonucleotides to protect mice against Francisella tularensis live vaccine strain but not fully virulent F. tularensis subspecies holarctica is reflected in cell-based assays.

Rees DG, Hartley MG, Green M, Lukaszewski RA, Griffin KF, Atkins HS, Lyons R, Krieg AM, Titball RW.

Microb Pathog. 2013 Oct;63:16-8. doi: 10.1016/j.micpath.2013.04.013. Epub 2013 May 22.

PMID:
23707360
13.

Trimethoprim/sulfamethoxazole (co-trimoxazole) prophylaxis is effective against acute murine inhalational melioidosis and glanders.

Barnes KB, Steward J, Thwaite JE, Lever MS, Davies CH, Armstrong SJ, Laws TR, Roughley N, Harding SV, Atkins TP, Simpson AJ, Atkins HS.

Int J Antimicrob Agents. 2013 Jun;41(6):552-7. doi: 10.1016/j.ijantimicag.2013.02.007. Epub 2013 Mar 19.

PMID:
23517714
14.

Assessment of antimicrobial peptide LL-37 as a post-exposure therapy to protect against respiratory tularemia in mice.

Flick-Smith HC, Fox MA, Hamblin KA, Richards MI, Jenner DC, Laws TR, Phelps AL, Taylor C, Harding SV, Ulaeto DO, Atkins HS.

Peptides. 2013 May;43:96-101. doi: 10.1016/j.peptides.2013.02.024. Epub 2013 Mar 14.

PMID:
23500517
15.

Galleria mellonella as a model system to test the pharmacokinetics and efficacy of antibiotics against Burkholderia pseudomallei.

Thomas RJ, Hamblin KA, Armstrong SJ, Müller CM, Bokori-Brown M, Goldman S, Atkins HS, Titball RW.

Int J Antimicrob Agents. 2013 Apr;41(4):330-6. doi: 10.1016/j.ijantimicag.2012.12.009. Epub 2013 Feb 8.

PMID:
23402703
16.

Bacterial TIR-containing proteins and host innate immune system evasion.

Rana RR, Zhang M, Spear AM, Atkins HS, Byrne B.

Med Microbiol Immunol. 2013 Feb;202(1):1-10. doi: 10.1007/s00430-012-0253-2. Epub 2012 Jul 8. Review.

PMID:
22772799
17.

A Toll/interleukin (IL)-1 receptor domain protein from Yersinia pestis interacts with mammalian IL-1/Toll-like receptor pathways but does not play a central role in the virulence of Y. pestis in a mouse model of bubonic plague.

Spear AM, Rana RR, Jenner DC, Flick-Smith HC, Oyston PC, Simpson P, Matthews SJ, Byrne B, Atkins HS.

Microbiology. 2012 Jun;158(Pt 6):1593-606. doi: 10.1099/mic.0.055012-0. Epub 2012 Mar 8.

PMID:
22403187
18.

Design and characterization of novel hybrid antimicrobial peptides based on cecropin A, LL-37 and magainin II.

Fox MA, Thwaite JE, Ulaeto DO, Atkins TP, Atkins HS.

Peptides. 2012 Feb;33(2):197-205. doi: 10.1016/j.peptides.2012.01.013. Epub 2012 Jan 24.

PMID:
22289499
19.

Neutrophils are the predominant cell-type to associate with Burkholderia pseudomallei in a BALB/c mouse model of respiratory melioidosis.

Laws TR, Smither SJ, Lukaszewski RA, Atkins HS.

Microb Pathog. 2011 Dec;51(6):471-5. doi: 10.1016/j.micpath.2011.07.002. Epub 2011 Jul 20.

PMID:
21798336
20.

Potent antimicrobial peptides with selectivity for Bacillus anthracis over human erythrocytes.

Dawson RM, Fox MA, Atkins HS, Liu CQ.

Int J Antimicrob Agents. 2011 Sep;38(3):237-42. doi: 10.1016/j.ijantimicag.2011.05.006. Epub 2011 Jul 8.

PMID:
21741801

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