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Items: 12

1.

GENE REGULATION. Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock.

Zhang Y, Fang B, Emmett MJ, Damle M, Sun Z, Feng D, Armour SM, Remsberg JR, Jager J, Soccio RE, Steger DJ, Lazar MA.

Science. 2015 Jun 26;348(6242):1488-92. doi: 10.1126/science.aab3021. Epub 2015 Jun 4.

2.

Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo.

Fang B, Everett LJ, Jager J, Briggs E, Armour SM, Feng D, Roy A, Gerhart-Hines Z, Sun Z, Lazar MA.

Cell. 2014 Nov 20;159(5):1140-52. doi: 10.1016/j.cell.2014.10.022.

3.

Carboxamide SIRT1 inhibitors block DBC1 binding via an acetylation-independent mechanism.

Hubbard BP, Loh C, Gomes AP, Li J, Lu Q, Doyle TL, Disch JS, Armour SM, Ellis JL, Vlasuk GP, Sinclair DA.

Cell Cycle. 2013 Jul 15;12(14):2233-40. doi: 10.4161/cc.25268.

4.

Evidence for a common mechanism of SIRT1 regulation by allosteric activators.

Hubbard BP, Gomes AP, Dai H, Li J, Case AW, Considine T, Riera TV, Lee JE, E SY, Lamming DW, Pentelute BL, Schuman ER, Stevens LA, Ling AJ, Armour SM, Michan S, Zhao H, Jiang Y, Sweitzer SM, Blum CA, Disch JS, Ng PY, Howitz KT, Rolo AP, Hamuro Y, Moss J, Perni RB, Ellis JL, Vlasuk GP, Sinclair DA.

Science. 2013 Mar 8;339(6124):1216-9. doi: 10.1126/science.1231097.

5.

A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex.

Armour SM, Bennett EJ, Braun CR, Zhang XY, McMahon SB, Gygi SP, Harper JW, Sinclair DA.

Mol Cell Biol. 2013 Apr;33(8):1487-502. doi: 10.1128/MCB.00971-12. Epub 2013 Feb 4.

6.

Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling.

Beirowski B, Gustin J, Armour SM, Yamamoto H, Viader A, North BJ, Michán S, Baloh RH, Golden JP, Schmidt RE, Sinclair DA, Auwerx J, Milbrandt J.

Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):E952-61. doi: 10.1073/pnas.1104969108. Epub 2011 Sep 26.

7.

Negative regulation of STAT3 protein-mediated cellular respiration by SIRT1 protein.

Bernier M, Paul RK, Martin-Montalvo A, Scheibye-Knudsen M, Song S, He HJ, Armour SM, Hubbard BP, Bohr VA, Wang L, Zong Y, Sinclair DA, de Cabo R.

J Biol Chem. 2011 Jun 3;286(22):19270-9. doi: 10.1074/jbc.M110.200311. Epub 2011 Apr 5.

8.

Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy.

Armour SM, Baur JA, Hsieh SN, Land-Bracha A, Thomas SM, Sinclair DA.

Aging (Albany NY). 2009 Jun 3;1(6):515-28.

9.

SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis.

Kim D, Nguyen MD, Dobbin MM, Fischer A, Sananbenesi F, Rodgers JT, Delalle I, Baur JA, Sui G, Armour SM, Puigserver P, Sinclair DA, Tsai LH.

EMBO J. 2007 Jul 11;26(13):3169-79. Epub 2007 Jun 21.

10.

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase.

Selak MA, Armour SM, MacKenzie ED, Boulahbel H, Watson DG, Mansfield KD, Pan Y, Simon MC, Thompson CB, Gottlieb E.

Cancer Cell. 2005 Jan;7(1):77-85.

11.

Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis.

Gottlieb E, Armour SM, Harris MH, Thompson CB.

Cell Death Differ. 2003 Jun;10(6):709-17.

12.

Mitochondrial respiratory control is lost during growth factor deprivation.

Gottlieb E, Armour SM, Thompson CB.

Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12801-6. Epub 2002 Sep 12.

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